DRUGS AFFECTING URINARY TRACT AND BLADDER ch 52

Question 1

What are conditions that affect the bladder and urinary tract

Answer 1

• Urinary tract infections (UTIs)
• Bladder spasms
• Bladder pain
• Benign prostatic hyperplasia

Question 2

Describe bph

Answer 2

• Enlargement of prostate, around urethra
• Leads to discomfort, difficulty initiating stream, bloating, cystitis
• Evaluate for other prostate pathology prior to treatment

Question 3

What are two types od drugs used to relive symptoms of bph

Answer 3

• Alpha-adrenergic blockers
• Drugs that block testosterone production

Question 4

What is tamsulosin (Flomax)?

Answer 4

used for treating bph

Question 5

What are therapeutic actions of tamsulosin (Flomax)?

Answer 5

Alpha1-adrenergic blocker
* Results in relaxation of SNS effects on bladder and urinary tract

First dose syncope

Question 6

What are adverse affects of tamsulosin (Flomax)?

Answer 6

• Postural hypotension
• Dizziness
• Sexual dysfunction

Question 7

what is finasteride(Proscar)?

Answer 7

Used for bph

Question 8

What is therapeutic actions of finasteride(Proscar)?

Answer 8

5-alpha reductase inhibitors – inhibit
enzyme involved in testosterone
production
* Reduces size of prostate gland
* Permits flow, emptying of bladder,
increases force of stream
Decreases PSA level even when
cancer present

Question 9

What are adverse affects of finasteride(Proscar)?

Answer 9

Decreased libido

Question 10

What are contras of finasteride(Proscar)?

Answer 10

Allergy

Question 11

What are cautions of finasteride(Proscar)?

Answer 11

Renal/hepatic disease
* Women – gloves when handling due to
risk for skin absorption (pregnancy
Category X)