18: Fibrous CT Flashcards
1
Q
Most abundant tissue type
A
CT
2
Q
ECM in bone
A
Mineralized
3
Q
Type I collagen function
A
Resists tension
4
Q
Most abundant protein in the body
A
Collagen
5
Q
Fibrils in collagen
A
Are secreted as pro-collagen, aligned and cross linked
6
Q
Type I collagen composition
A
2 collagen type a1 chains + 1 collagen type a2 chain
7
Q
Syndecans
A
Receptors that bind GF
8
Q
Syndecans composition
A
Contain multiple Heparan sulfate proteoglycans
9
Q
CD44: what it binds
A
Hyaluronan
10
Q
Four types of membranes
A
Mucous, serous, cutaneous, synovial
11
Q
What is a membrane?
A
Epithelium + CT
12
Q
Cutaneous membrane
A
Skin
13
Q
Mutation in Marfan’s syndrome
A
Fibrillin-1 gene
14
Q
Fiber type affected in Marfan’s
A
Elastin
15
Q
Genetics of Marfan’s syndrome
A
Autosomal dominant
