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laboratory animal test 1 Flashcards

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0
Q

Coordinates animal care and advises investigators on proper animal use

A

Laboratory animal veterinarian

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1
Q

How do the laboratory animal and research professionals who are members of AALAS view the use of animals in research?

A

As a privilege

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2
Q

Performs many animal care functions and monitors environmental factors

A

Laboratory animal technician

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3
Q

Plans and coordinates all phases of the research work and prepares the protocol

A

Principal investigator

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4
Q

Performs research tasks required by the protocol and analyzes data

A

Research technician

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5
Q

Primary source of the standards and guidelines for laboratory animal care and use in the United States

A

Guide for the Care and Use of Laboratory Animals

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6
Q

Federal mandate that covers all live vertebrate used or intended for use in research, research training, experimentation, biological testing, or for related purposes

A

PHS policy

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7
Q

Written instructions approved by management and used to perform a routine activity

A

Standard Operating Procedure

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8
Q

A document written by the Principal Investigator and approved by the IACUC, that describes and justifies the use of animals for a project

A

Animal use protocol

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9
Q

Regulations developed by the Food and Drug Administration and the Environmental Protection Agency to validate and document the processes of safety testing

A

Good laboratory practices

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10
Q

The appropriate use of analgesics in postsurgical animals would apply to which of the 3 Rs principles?

A

Refinement

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11
Q

An institutional unit that ensures compliance with the Good Laboratory Practices

A

Quality assurance unit

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12
Q

A nonprofit organization that accredits a laboratory animal research programs

A

Association for the Assessment and Accreditation of Laboratory Animal Care International

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13
Q

An institutional body that oversees and evaluates an animal care and use program

A

Institutional Animal Care and Use Committee

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14
Q

The body that administers and enforces the PHS Policy

A

Office of Laboratory Animal Welfare

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15
Q

The body that administers and enforces the Animal Welfare Regulations

A

Animal and Plant Health Inspection Service

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16
Q

Using 100 mice in a research study instead of 150 would be an example of which of the 3 Rs?

A

Reduction

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17
Q

Describes ways to prevent and address security breaches

A

Security plan

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18
Q

Provides the steps for disaster preparedness and response

A

Disaster plan

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19
Q

Measures the effectiveness of institution-wide emergency systems

A

Disaster drill

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20
Q

Identifies whom to call when an emergency occurs

A

Emergency contact list

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21
Q

Identifies ways to improve the disaster plan and emergency procedures

A

Post-incident discussion

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22
Q

What type of device identifies individuals using distinct characteristics such as fingerprints or eye structures?

A

Biometric scanner

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23
Q

What document should be posted throughout the facility, and it is consulted and used when there is an emergency?

A

Contact list

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24
Q

Virus carried by Old World macaque monkeys

A

B virus

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25
Q

Disease that can be transmitted from animals to humans

A

Zoonosis

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26
Q

Emission of energy rays through the air and other matter

A

Radioactivity

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27
Q

Parasite that can be transmitted through cat feces

A

Toxoplasma Gondi

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28
Q

Respirator mask that protects against airborne particles

A

N95

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29
Q

Provide information on toxicity and potential side effects, and describes recommended treatment for exposures

A

Material safety data sheets

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30
Q

Designing a workplace to minimize fatigue, discomfort, or injury

A

Ergonomics

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31
Q

A unit which measures loudness

A

Decibel

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32
Q

Zoonotic disease carried by nonhuman primate

A

Tuberculosis

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33
Q

Zoonotic disease carried by sheep

A

Q-fever

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34
Q

Zoonotic disease carried by cats

A

Toxoplasmosis

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35
Q

Zoonotic disease carried by macaque monkey

A

B virus

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36
Q

What is the first step to take if a dog bites your hand and the skin is broken?

A

Get first aid for the injury

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37
Q

Most likely cause of excessive noise in facility

A

Machinery

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38
Q

Microorganism that causes a disease in humans

A

Hazard

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39
Q

A biological agent that is a threat to humans or animals

A

Hazard

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40
Q

Designed to be thrown away after use

A

Disposable

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41
Q

Set of clothes worn for work

A

Uniform

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42
Q

Injuries such as sprains and strains

A

Musculoskeletal

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43
Q

A cut with jagged edges

A

Laceration

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44
Q

Used to block the body from radiation

A

Shielding

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45
Q

Protective mask that filters inhaled air

A

Respirator

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46
Q

Protective eyeglasses

A

Goggles

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47
Q

Disposable head cover

A

Bonnet

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48
Q

Common symptoms of this condition are nasal discharge,itchy eyes, and skin rashes

A

Allergy

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49
Q

Freedom from danger, risk, or injury

A

Safety

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50
Q

Type of glove that may cause contact skin allergy

A

Latex

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51
Q

Study of workplace design for efficiency and safety

A

Ergonomics

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52
Q

Term for hazards such as hypodermic needles and scalpel blades

A

Sharps

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53
Q

Viral illness common in winter months

A

Influenza

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54
Q

Emission of energy rays

A

Radioactivity

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55
Q

Substance capable of inducing unusual sensitivity

A

Allergen

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56
Q

Regular upkeep of equipment

A

Maintenance

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57
Q

Sterilizer that uses high temperature and pressure

A

Autoclave

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58
Q

Disease transmitted between animals and humans

A

Zoonosis

59
Q

Examination of a dead animal

A

Necropsy

60
Q

Personal cleanliness

A

Hygiene

61
Q

Corrosive or burning

A

Caustic

62
Q

Unit used to measure loudness

A

Decibel

63
Q

These can be toxic when inhaled

A

Fumes

64
Q

Who submits the Animal Welfare Assurance of Compliance that the animal research program meets all relevant regulations and standards?

A

Institutional official

65
Q

Which of the following is not one of the AALAS Technician Certification levels?

A

Registered veterinary technician (RVT)

66
Q

Which is not a required skill for ALATs?

A

Diagnosing diseases in animals

67
Q

Which of the following provides the most valuable information about the research animals’ health and environment?

A

Accurate, up-to-date records

68
Q

What helps to ensure that the data collected are not influenced by factors related to animal management?

A

Consistency

69
Q

Which of the following warm-blooded vertebrates are not regulated by the animal welfare act?

A

Purpose-bred rats

70
Q

What nonprofit organization accredits laboratory animal research programs?

A

Association for the assessment and accreditation of laboratory animal care international

71
Q

What guidelines must an animal facility follow when research animals are euthanized at the end of a study?

A

AVMA Guidelines on Euthanasia

72
Q

Beyond food, water, shelter, and healthcare requirements, to comply with the Animal Welfare Act, what must be provided to dogs in a laboratory animal research facility?

A

Opportunities for exercise

73
Q

To whom is the Animal Welfare Assurance of Compliance Statement submitted?

A

Office of Laboratory Animal Welfare

74
Q

Which is not a requirement of the Animal Welfare Act and Animal Welfare Regulations that a laboratory Animak research facility housing covered species must meet?

A

Participation in AAALACs assessment and accreditation programs

75
Q

What does the acronym “SOP” stand for?

A

Standard operating procedure

76
Q

What are the 3 Rs?

A

Replacement, refinement, reduction

77
Q

Who administers the Animal Welfare Regulations?

A

Animal and plant health inspection service (APHIS) of the United States Department of Agriculture (USDA)

78
Q

How often must an IACUC perform inspections of the facility?

A

Envy 6 months

79
Q

Who has the authority to sign the PHS Assurance?

A

The Institutional Official

80
Q

Who reviews all animal use protocols at the institution before studies using animals can begin?

A

IACUC

81
Q

How often does the Animal and Plant Health Insoection Service (APHIS) inspect the animal research facility?

A

At least once a year

82
Q

Which regulations apply to animal and non-animal research and safety studies funded or reviewed by the Food and Drug Administration and the Environamental Protection Agency?

A

Good laboratory practices

83
Q

What is the role of a quality assurance unit?

A

To ensure compliance with the GLPs

84
Q

Which type of SOP addresses procedures specific to each study?

A

Procedural

85
Q

The appropriate use of analgesics in postsurgical animals applies which principle of the 3 Rs?

A

Refinement

86
Q

Records of USDA inspections are available to the public under a provision of which federal law?

A

Freedom of Information Act

87
Q

Which statement is true regarding the facility’s disaster plan?

A

Hallways and other walkways should be kept clear and free of equipment in case of an emergency

88
Q

Which is not a good way to prevent security breaches?

A

Ask anyone you see in the animal facility why they are there

89
Q

Which situation would not be necessary to report to your supervisor?

A

A new employee working in another project asking about your work

90
Q

Which document contains information regarding potential disasters, evacuation, and emergency contacts?

A

Disaster plan

91
Q

Who develops the disaster plan?

A

Senior management and safety officials

92
Q

What is the best way to measure the effectiveness of an institution-wide emergency system?

A

Periodic disaster drills

93
Q

Which if these involves the development of methods for uniquely recognizing humans based upon physical features?

A

Biometrics

94
Q

What is the best defense against security breaches?

A

Employees who are aware of their surroundings

95
Q

Which if the following facilities would generally have the lowest risk of being targeted by animal rights activists?

A

Facilities housing fish and amphibians

96
Q

If you are present in the facility when a major disaster or accident occurs, what should be your first priority?

A

Protecting human life

97
Q

Where should the contact list be posted?

A

In common areas that have heavy traffic

98
Q

Why is it especially important that a background check is done for potential new employees of an animal research facility?

A

To avoid hiring anyone opposed to the use of animals in research

99
Q

What information does a disaster plan contain?

A

The steps for disaster preparedness and response

100
Q

In a disaster situation, when should the animals be evacuated?

A

When doing so does not jeopardize the safety of the staff

101
Q

What is the value of conducting a post-incident discussion?

A

To identify ways to improve emergency procedures

102
Q

What should be the first step if a technician is bitten by an animal in the animal facility?

A

The wound should be scrubbed and held under running water for 15 minutes

103
Q

Which federal agency enforces rules or standards related to workplace safety?

A

The Department of Labor’s Occupational Health and Safety Administration (OSHA)

104
Q

Above what level is noise considered a hazard to your hearing?

A

85 decibels

105
Q

What does an eye wash station use to clean the eye?

A

Clean water under low pressure

106
Q

What is radioactivity?

A

A release of energy rays

107
Q

Which type of hazard causes musculoskeletal injuries?

A

Ergonomic

108
Q

What is the term for a disease that can be transmitted between animals and humans?

A

Zoonosis

109
Q

What is the top priority when an accident results in an injury?

A

First aid

110
Q

Which of these provide information on the toxicity of chemicals?

A

Material safety data sheet (MSDS)

111
Q

Whose standards specifically address the storage and handling of radioactive materials in the facility?

A

Nuclear regulatory commission (NRC)

112
Q

Which aspect of the annual health screen is especially important for animal care staff working with primates?

A

Tuberculin skin test

113
Q

What type of injury can be prevented by taking frequent short breaks to rest and stretch the body?

A

Repetitive motion

114
Q

Sterilizes instruments, equipment, and glass items using superheated steam and pressure

A

Autoclave

115
Q

Burns material such as animal tissues, trash

A

Incinerator

116
Q

Uses a sliding beam and weighing platform to determine weights

A

Balance

117
Q

Protects the user from exposure to pathogenic microorganisms

A

Class III BSC

118
Q

Protects the user from chemical fumes

A

Fume hood

119
Q

What two features of a cage dumping station help protect the technician during cage changing?

A

The air-circulating fan and HEPA filter

120
Q

What chemicals are often added to animal’s drinking water to reduce bacterial contamination?

A

Acid and chlorine

121
Q

What type of cage washer is best used for cleaning larger pieces of equipment such as bulk carts and cage racks?

A

Rack washer

122
Q

Metabolism cages are most commonly used with which of the following types of laboratory animals?

A

Rodents

123
Q

Squeeze cages are typically used to hold which species of animals?

A

Nonhuman primates

124
Q

Nesting materials, toys, foraging devices, and food treats are examples of which of the following:

A

Environmental enrichment

125
Q

What type of cage allows for collection of spilled feed and water and collection of urine and feces in separate tubes?

A

Metabolism

126
Q

What type of caging is the term “jump box” used to describe?

A

Transfer cage

127
Q

What type of cage washer is best used for cleaning large numbers of smaller pieces of equipment such as rodent cages, or feed bowls?

A

A tunnel washer

128
Q

What is the most sensitive method to monitor autoclave effectiveness?

A

Using a biological indicator

129
Q

What precautions must be taken when autoclaving a liquid substance in a bottle?

A

Liquid containers should not be tightly sealed or completely filled because the liquid will expand as the temperature rises

130
Q

Which of the following spis an item that should never be autoclaved?

A

Flammable liquid

131
Q

What should you do if you notice that one of the safety valves on the cage washer is not working correctly?

A

Tell your supervisor immediately

132
Q

Which bio safety cabinets are known as “glove boxes”?

A

Class III

133
Q

Cleaning assessment using a RODAC (replicate organism detection and counting) plate, involves:

A

Microbial growth in a nutrient medium

134
Q

Which equipment is often used on loading docks to decontaminate items such as bags of feed and bedding?

A

Mister

135
Q

Which equipment can be used to decrease the incidence of ergonomic injuries associated with handling water bottles?

A

Automated watering system

136
Q

In an automated watering system, what device mechanically lowers the water pressure for delivery to the individual cages?

A

Pressure reducing station

137
Q

What can happen if a drinking valve I a rodent cage remains stuck in the open position?

A

The cage will flood

138
Q

How does a laminar flow cabinet protect the worker who is changing a cage?

A

Air in the cabinet does not exit out the front

139
Q

What kind of caging creates a barrier at the cage level, allowing greater control. Of the individual cage environment?

A

Microisolation

140
Q

What are squeeze cages used for?

A

Restraining the animal within its cage

141
Q

What types of animals are usually housed in a squeeze cage?

A

Nonhuman primates and hoof stock

142
Q

Which if the following statements about the size of animal caging is false?

A

The size of the floor space includes areas occupied by food and water containers

143
Q

What should be done to rodent shipping containers when they are received?

A

Spray them down with disinfectant

144
Q

In general, what type of cage is used to house groups of animals of the same species together?

A

Group

From Flashcardlet (28 decks)

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