2/13/17 DURRANT Skin and soft TIssue infection TEST #2 Flashcards

(71 cards)

1
Q

What is the first line of defense for soft tissue infections?

A

-Intact skin (physical barrier)

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2
Q

_____ of skin structures permit microbial invasion?

A

-Ducts

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3
Q

T/F Trauma can also permit microbial invasion.

A

-True

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4
Q

What are the four medical terms that are used to describe soft tissue infections?

A
  • Rubor
  • Calor
  • Tumor
  • Dolor
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5
Q

What are five things you might see on a physical examination of a soft tissue infection?

A
  • Crepitus
  • Necrosis
  • Fluctuance
  • Purpura
  • Bullae
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6
Q

What are six other disease that can mimic Skin and Soft tissue infections?

A
  • Gout
  • Thrombophlebitis
  • Deep vein thrombosis
  • Contact dermatitis (example latex allergy)
  • Drug eruption
  • Foreign body reaction
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7
Q

What is the number one bacteria that causes folliculitis?

A

-Staph aureus

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8
Q

What organism causes hot tub folliculitis?

A

-Pseudomonas aerguinosa

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9
Q

What is the basic treatment for folliculitis?

A
  • Soap and water

- Topical antibiotics

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10
Q

What is a common cause of acne?

A

-Propionibacterium acnes

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11
Q

T/F Staph aureus can cause acne

A

True

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12
Q

Where does propionbacterium acnes multiply in?

A

-Sebum trapped in follicles/glands

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13
Q

What is the most common cause of soft tissue abscesses?

A

-Staph aureus

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14
Q

When you have a soft tissue abscess what causes local superficial cellulitis?

A

Bacteria

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15
Q

When you have necrose/liquefy tissue in a soft tissue abscess what does that consist of?

A
  • Cellular debris

- WBCs (pus)

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16
Q

What do you do to treat soft tissue abscesses?

A
  • Incision and drainage

- Systemic antibiotics

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17
Q

T/F Soft tissue abscesses are often polymicrobial

A

True

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18
Q

What is an abscess in the area of a hair follicle also known as a boil?

A

-Furuncle

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19
Q

What is a multiloculated abscess?

A

-Carbuncle

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20
Q

When you have a carbuncle where can the infection spread to?

A

-Subcutaneous tissue

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21
Q

What is the treatment of a carbuncle?

A
  • Incision

- Drainage

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22
Q

What is the disease of an enzyme producing bacteria that digest fascial barrier, and cause tissue necrosis?

A

-Necrotizing fasciitis

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23
Q

What is the main cause of necrotizing fasciitis?

A

-Group A strep

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24
Q

T/F Only gram + bacilli create spores

A

True

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25
What is a polymicrobial infection of the genitals and perineum called?
-Fournier's gangrene
26
What is the hallmark finding of necrotizing fasciitis?
-Huge amount of pain compared to exam findings
27
What is the most common pathogen found in surgical wounds?
-Staph aureus
28
What is the gram stain of staph aureus?
-Gram + cocci in clusters
29
What are three sources of surgical wounds pathogens?
- Patients own skin/normal flora - Fomites (door handle, drinking fountain etc.) - Hands - Air - Environment
30
What is the best way to keep surgical wounds from becoming infected?
-Preoperative antibiotics
31
When you have fungal infections what is the most common one seen?
-Dermatophyte fungi (superficial hair, skin, and nail infections)
32
What is the most common yeast infection?
-Candida albicans
33
What do you do to treat Candida albicans?
- Topical antifungals | - Systemic antifungals if severe
34
What three things can candida albicans cause?
- Diaper rash - Thrush - Intertrigo
35
Is impetigo highly contagious?
-Yes
36
How do you treat impetigo?
- Penicillin | - Topical antibiotic
37
What is a honey crust lesion known as?
-Impetigo
38
What are the top two causes of Impetigo?
- Group A strep | - Staph aureus
39
What is a painful red looking disease that is hot to the touch and found in the deep layers of dermis?
Erysipelas
40
What causes Erysipelas?
-Group A strep
41
What is the treatment for Erysipelas?
-Penicilin
42
What is a painful red looking disease that is found in the subcutaneous tissue?
-Cellulitis
43
What is the main cause of Cellulitis?
-Group A strep
44
What is the treatment of cellulitis?
-Systemic antibiotics
45
T/F If you have a higher number of organisms it increases your risk of wound infections
True
46
If you have a lower number of virulence organisms is will increase your risk of wound infections
False | -A higher number of virulence
47
What is the "all time champion" of microbial pathogens
Staph aureus
48
T/F You usually see a lot of pus if it is a staph aureus infection
True
49
What type of lesions does staphyaureus cause?
- Acute - Aggressive - Locally destructive purulent
50
What type of Staph toxin causes scalded skin syndrome?
-Alpha-toxin (exotoxin)
51
What type of staph toxin causes bullous impetigo?
-Exfoliatin
52
What type of Staph toxin causes Toxic shock syndrome?
-TSST-1
53
What type of Staph toxin causes stphylococcal food poisoning?
-Enterotoxin (Exotoxin that effects the gut)
54
What gene do MRSA strains acquire?
-MecA gene (altered penicillin binding protein)
55
MSSA or MRSA is resistant to all B-lactams?
-MRSA
56
What are four risk factors for MRSA?
- Close skin to skin contact - Crowded living conditions - Poor hygiene - IV drug users
57
What are five antibiotics that you can use to treat MRSA?
- Trimethoprim-sulfa - Doxycycline - Vancomycin - Linezolid - Daptomycin
58
What does a Group A strep look like?
-Gram + cocci in chains
59
Streptolysins O and S are cytotoxic or non-cytotoxic?
-Cytotoxic
60
T/F Streptolysins O and S lyse leukocytes, tissue cells, and platelets
True
61
What type of strep toxins are superantigens?
-Pyrogenic exotoxins A and B
62
What are three inflammatory enzymes produced by group A strep?
- Streptokinase (protease) - Hyaluronidase (degrades carbohydrates) - DNase (degrades DNA)
63
What is an anaerobic spore forming gram+ rod with square ends?
-Clostridium perfringens
64
What type of gas does Clostridium perfringens produce in tissue?
- Hydrogen | - CO2
65
What type of gram stain is Pasteurella multocida?
-Gram - Rod
66
What causes Pasteurella multocida?
-Animal bites
67
What type of gram stain is Pseudomonas aeruginosa?
-Gram - Rod
68
What type of gram stain is Vibrio vulnificus?
-Gram - Rod
69
Where do you find Vibrio Vulnificus?
-Salt walter environments
70
What is Vibrio vulnificus associated with?
- Iron overload | - Cirrhosis
71
What causes Mycetoma?
- Actinomycyes | - Nocardia