2010 module exam Flashcards
(85 cards)
1
Q
Which structure is responsible for storage and maturation of sperm?
A
Epidydimis
2
Q
What is the function of granulosa cell?
A
Secrete estrogen
3
Q
Uretric bud will give us which of the following structure?
A
Collecting duct
4
Q
What is a special characteristic of breast?
A
Modified apocrine sweat glands
5
Q
What supplies the medial aspect of the breast?
A
Internal mammary artery
6
Q
What supplies the prostate?
A
Inferior vesical artery (which gives us the prostatic artery)
7
Q
What attaches to the labia majora?
A
Round ligament
8
Q
Which of the following is a remamnt of the guberniculum ?
A
Round ligament
9
Q
What originates from coelomic epithelium?
A
Sertoli cells
10
Q
Which of the following is a part of the pelvic diaphragm ?
A
Coccygues muscle
11
Q
Which node drains from the superior part of the vagina?
A
Internal iliac artery
12
Q
Which nodes drains the testes?
A
Lumbar node
13
Q
Which efferent nerve fiber is responsible for emission?
A
Lumbar sphlencnic
14
Q
What originates from para mesonephric tube in females?
A
Uterine tube
15
Q
What originates from mesonephric duct in males?
A
Vas deferns
16
Q
What gives nourishment for the semen/sperm?
- Seminal vesicle
- Glandular prostate
A
- Seminal vesicle? (not sure)
17
Q
Which of the following nerves must be blocked during episiotomy?
A
Pudendal nerve
18
Q
Fallopian tube is embedded in which structure?
A
Broad ligament
19
Q
In the breast we have a major bulk of nodes, where does it all eventually drains to?
- Central node
- Subscapular nodes
- Deep cervical nodes
- Subclavian nodes
A
- Subclavian nodes
20
Q
Thoracodorsal nerve is injured during resection of which lypmph nodes?
- Central nodes
- Subscapular nodes
- Deep cervical nodes
- Parasteral nodes
A
- Subscapular nodes (we think this is the answer since these nodes located posteriorly)
21
Q
Breast cancer metastases into vertebral column via which route?
A
Intercostal vein
22
Q
What nerve is responsible for erection?
A
Sacral sphalncnic
para symphathatic innervations to the peins
23
Q
Specimen from the breast was resicted, it had many cysts with adenosis foci?
A
Fibrocystic change
24
Q
A 50 year old women with masses on the breast bilaterally which turned out to be carcinioma which type was it?
- Ductal carcinoma
- Lobar carcinoma
A
- Lobar carcinoma
25
Breast specimen showed slit like gland and whorled appearance ?
Fibroadenoma
26
Breast specimen contain fibrous tissue invading the surrounding fat?
Prolifrative breast disease (not sure)
27
Breast specimen showed cyst with apocrine metaplastic changes?
Fibrocystic change
28
Patient with gastric cancer developed an ovarian tumor?
Krukenberg
29
What characterize granulose cell tumor?
- 10% of all malignant cancer
- Has a poor prognosis
- A germ cell tumor
- 10% of all malignant cancer( we think this is the answer)
30
Histology slide shows a prostatic tissue near to the normal appearance , what is the gleason grade?
Grade 1
31
A patient with gleason score= 10, what does it indicate?
Poorly differentiated prostatic tissue
32
What is the cause of bilateral hydronephrosis in a 55 year old male?
Benign prostatic hyperplasia
33
Well difeined masses found in the subserousal, submural, intramural myometrium?
Leiomyoma
34
Smooth muscle neoplasm with cigar shaped nuclei, spindle cells, no atpyia and no mitosis?
Leiomyoma
35
What is the mechanism of action of intrauterine device in contraception?
Thicking of cervical mucosa
36
A young female with abdominal discomfort for 6 months, came with an ovarian cyst containing sebacues material and teeth?
Dermoid cyst
37
Male phenotype with XX chromosome ?
Translocation of SRY gene
38
An Iranian child with hypernatremia and ambiguous genetilia ?
Decrease in II-beta hydroxylase
39
Histological examination of ovarian tissue of 18 year old girl showed fibrous bridges with no ova, what do you think the cytological diagnosis will be?
45X/46XX
40
What is the most dangerous fracture in postmenopausal women?
Neck of the femur fractures
41
Placenta with no fetus and full of fluid vesicles?
hydatifirim moles
42
What is the cell that synthesizes hCG?
Syncytrophoblast
43
What does synytrophoblast synthesize ?
Human chorionic gonadotropin
44
In pre-eclampsia, you have autoantibodies against?
- Angiotensin 1 receptor
- Inhibin a
- Inhibin b
- TNF alpha
- Nitric oxide synthase
- Angiotensin 1 receptor
45
What is released during process of capacitation from sperm?
Cholesterol
46
What inhibits the viability of sperm in the female tract?
Lipid peroxidation
47
Large placenta composed of oedematous immature chorionic villi?
Diabetes
48
When does type 1 mammary gland develops?
Puberty
49
A patient with glactorrhea and amenorrhea ?
Prolactin
50
Which hormone minimizes postpartum blood loss?
Oxyctocin
51
What does glactokineses indicate?
- Production of milk
- Transmission of signals from breast to the supraoptic nuclei
- Transmission of signals from breast to the supraoptic nuclei
52
Why the placenta has decreased permeability during 1st trimester ?
Increased Thickness of placental membrane
53
What is a contraindication of combined oral contraceptive?
- Myocardial infarction
- Endometrial cnacer
- Myocardial infarction (obgyn 3, slide 9)
54
Pregnant woman on valporic acid develop seizure after 26 weeks, what is the pharmacological cause?
- Decrease in steady state concentration
- Decrease in CYR450 oxidase
- Decrease in steady state concentration
55
When does implantation occur?
- Two days after fertilization
- Two days after ovulation
- A week after fertilization
- A week after fertilization
56
What is the mechanism of action of clomophine?
Stops inhibitory effect of estrogen on LH/FSH
57
What is characteristic of hormonal replacement therapy on post- menopausal women?
- Restore bone loss
- It must be started as soon as postmenopausal sings appear to have
better results
- Used in higher doses than contraceptives
- It must be started as soon as postmenopausal sings appear to have
better results
58
Which drug has a toxic effect on sperms?
Gossypyl
59
Binding of sperm on zona pelucida will trigger....
Acrosomal reaction
60
In acrosomal reaction, the major event happening is ?
Release of protease
61
Alpha fetoprotein is released in which tumor?
- Endodermal sinus
- Dermoid
- Endodermal sinus
62
Degredation of p53?
E6
63
Bind to RB?
E7
64
Is used in HPV vaccination?
L1
65
Definitive cause of infertility ?
antiovarian antibodies
66
What regulates mother tolerance to the fetus?
Immune suppressive factors
67
How does antiphospholipid cause recurrent miscarriage?
Damage to trophoblast cells
68
What is the most common mutation(abnormality) detected when examining chrionic villi ?
- Trisomy 21
- Trisomy 13
- Trisomy 21
69
50 year old women presented with retracted nipple+ lump, which imaging modality do you use?
Mammography
70
A woman presented with lower abdominal mass, what is the 1st method of diagnosis?
Ultrasound
71
Drug causing nasal hypoplasia?
Warafrin
72
Female with flextion of 5 fingers and gave birth with a baby with down syndrome?
47 XXX
73
Drug causing oligohyramnios?
ACE inhibitor
74
Endometrial mass projecting into cavity is associated with tamoxifin use
Endometrial polyps
75
We want to do a case-control study to find relation between bladder cancer and smoking, so we took cases from oncology clinic and controls from same clinic and did age matching, do you think control selection was good?
No, smokers will be overestimated
76
Why does masculinization increase to some degree in patients with 5 alpha reductase type 2 in puberty?
Type 1 5 alpha reductase in liver will convert testosterone to di-
hydrotestosterone
77
We did a study to find relation between family history and renal disease, the hazard ratio =2.1, from this info what do you think the test study modality ?
Cohort - time to event - cox
78
32 year old women complaining of bleeding, colposcopy was done and a sample was collected from endometrium, which showed dysplasia involving full thickness of endometrim without invasion
- CIN 1
- CIN 2
- CIN 3
- Carcinoma
- CIN 3
79
Most classical feature about type 2 5 alpha reductase deficiency ?
Only affect males
80
Valporic acid in pregnancy can cause?
Neural tube defects
81
What is the enrgy supply of sperm for motility?
Glycolysis
82
What is the most common zone for benign prostatic hyperplasia?
Periurethral
83
Which drug causes testicular atrophy?
Spirolactone
84
A woman with 3 children developed urinary incontinence , what's damaged with the multiple deliveries?
- Pelvic diaphragm
- Tendinous arch of pelvic fascia
- Perineal membrane
- Pelvic diaphragm (levator ani) (anatomy 3 slide 16) "levator ani has an important function in the voluntary control of urination, fecal continence, and uterine support"
85
Drug used in advanced breast cancer?
Tamoxifin
