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Flashcards in 2013 Block A Deck (97)
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1

Premature infants develop iron deficiency anemia more than normal infants because:
a. Absorption of iron is deficient
b. infants with low birth weight have reduced iron stores
c. usually the mother has reduced iron stores
d. food intake is deficient

B

2

The following is associated with microcytic, hypochromic red cells
a. renal failure
b. thalassemia
c. cirrhosis
d. folic acid deficiency

B

3

The most common cause of iron deficiency in a new born is
a. low birth weight
b. mother has iron deficiency anemia
c. frequent phlebotomy for diagnostic purposes
d.. decreased iron intake

C

4

The gold standard to determine body iron content is
a.. serum iron
b. total iron binding capacity
c. serum ferritin
d. hemosiderin determination in the bone marrow

D

5

The most common cause of iron deficiency anemia in males is
a. deficient iron intake
b. deficient iron absorption
c. blood loss
d. impaired metabolism of iron

C

6

Iron supplement should be given to a pregnant woman because of
a. increased requirement by mother and fetus
b. presence of iron deficiency state before pregnancy
c. defective iron absorption because of morning sickness
d. decreased intake of iron during pregnancy because of idiosyncrasies

A

7

Which of the following laboratory measurements is useful to determine response to iron in an iron deficient patient?
a. serum iron determination
b. hemoglobin determination
c. hematocrit determination
d. reticulocyte count

D

8

Which of the following is rich in iron?
a. cereal
b. meat
c. green leafy vegetable
d. fish

B

9

Iron therapy is often continued for 6 months even if the hemoglobin has normalized because
a. it acts as prophylaxis against future blood loss
b. most diet is usually deficient in iron
c. iron stores in the body has to be replenished
d. it contributes to the wellbeing of the patient

C

10

Which of the following is false
a. Packed RBC is potentially infected if kept at room temperature for a long period of time
b. an infected donor can transmit his infection to the recipient
c. improperly performed phlebotomy during blood donation is a potential source of infected blood
d. platelet concentrate should be stored at 5°C

D

11

Which of the following is a reason for permanent donor deferment?
a. presence of upper respiratory tract infection
b. ingestion of anti-pyretics
c. history of malaria
d.history of anemia

C

12

Why is refrigerated centrifuge used in separating blood components
a. to keep the optimum temperature constant during spinning
b. for easier separation of the components
c. to evenly pack the red cells
d. to harvest more platelets

A

13

The shelf life of packed RBC in the blood bank refrigerator depends on
a. health of the donor
b. the amount of blood donated
c. the storage temperature
d. the type of anticoagulant used

D

14

Platelet concentrates need to be constantly agitated because
a. the lifespan of platelets can be prolonged
b. platelets tend to aggregate
c. agitation prevents infection
d. the storage time can be prolonged

B

15

increased levels of homocysteine is a risk factor for the development of thrombosis because it
a. causes damage to the endothelium of blood vessels
b. combines with platelet to initiate coagulation
c. increases the levels of all coagulation factors
d. decreases anti-fibrinolytic activity

A

16

Oral contraceptive is not given to a woman who have a high predisposition for thrombosis because it
a. damages the arterial blood vessel
b. causes elevation of coagulation factors
c. increases fibrinolysis
d. promotes platelet adhesion

B

17

Which of the following is not associated with a hypercoagulabe state
a. Protein C deficiency
b. Protein S deficiency
c. Anti-thrombin 3 deficiency
d. increased fibrinolysins

D

18

The most serious complication of Deep Vein thrombosis is
a. pulmonary embolism
b. cyanosis of the lower extremity
c. varicose ulcers
d. arterial thrombosis

A

19

Arterial thrombosis is initiated by
a. platelet adhesion and aggregation
b. increased coagulation factors
c. defective fibrinolysis
d. blood stagnation

A

20

Thromboxane A promotes the development of thrombosis by
a. inducing vasodilation
b. inducing vasoconstriction
c. damage to endothelium
d. neutralizing anti-Thrombin III

B

21

Certain tumors have a predisposition to develop thrombosis because
a. they cause erosion of blood vessels
b.. they have an effective fibrinolytic activity
c. they express excess tissue factor that activates coagulation
d. they are associated with defective platelet function

C

22

Indication for anticoagulation in a patient with Protein C deficiency
a. recurrent thromboembolism
b. pregnancy
c. concomitant diabetes mellitus
d. presence of hypertension

A

23

Antiphospholipid Antibody Syndrome (APAS) should be suspected in this condition
a. recurrent Deep Vein Thrombosis
b. recurrent fetal loss
c. pulmonary embolism
d. arteriosclerosis in the young

B

24

In this condition, thrombosis occurs because the endothelium of the blood vessels is altered by the deposition of immune complexes
a. severe sepsis
b. vasculitis
c. pregnancy
d.. massive trauma

B

25

Which of the following promotes the development of a thrombus
a. plasmin
b. thrombomodulin
c. heparin
d. tissue factor activation

D

26

Prophylactic anticoagulant is used in orthopedic surgery to prevent venous thrombosis which may develop as a result of
a. immobilization
b. venous stasis
c. extensive surgery
d. arteriosclerosis

A

27

One of the more common causes of aplastic anemia is:
a. exposure to benzene compounds
b. exposure to ionizing radiation
c. overwhelming infection
d. genetic inheritance

A

28

An infectious state that is occasionally associated with bone marrow suppression is:
a. strep throat
b. hepatitis
c. chicken pox
d. pheumococcal pnemonia

B

29

Peripheral blood cell morphology in aplastic anemia is usually:
a. normocytic, normochromic
b. microcytic, hypochromic
c. macrocytic, normochromi
d. microcytic, normochromic

A

30

For children and young adults with severe aplastic anemia, the treatment of choice is:
a. immunosuppresive therapy
b. bone marrow transplant
c. androgen
d. supportive therapy

B