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Flashcards in 2014 Block A Deck (86)
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1

The shelf life of packed RBC in the blood bank refrigerator depends on:

A. Health of donor
B. The amount of blood donated
C. The storage temperature
D. The type of anticoagulant used

D

2

Oral contraceptive use is not given to women who have high predisposition for thrombosis because it:

A. damages arterial blood vessel
B. causes elevation of coagulation factors
C. increases fibrinolysis
D. promotes platelet adhesion

C

3

Which of the following is not a hypercoagulable state?

A. Protein C deficiency
B. Protein S deficiency
C. Antithrombin III deficiency
D. Increased fibrinolysis

D

4

Certain tumors have a predisposition to tumors because:

A. promote erosion of blood vessels
B. increased fibrinolytic activity
C. release tissue factor that promote coagulation
D. decreased platelet activity

C

5

APAS should be suspected in which of the following:

A. recurrent DVT
B. recurrent fetal loss
C. pulmonary embolism
D. arteriosclerosis in the young

B

6

These agents frequently but not inevitably produce bone marrow aplasia:

A. Benzene
B. Chloramphenicol
C. Insecticides
D. Estrogen

A

7

Treatment of folate deficiency:

A. oral replacement of 1 to 5 gm/day folic acid
B. parenteral folate replacement
C. oral folic acid 1 to 5 gm/day with ferrous supplement
D. A and C

A

8

The following is/are characteristic(s) of intravenous hemolysis in contrast to extravenous hemolysis:

A. Presence of hemosiderin in urine
B. Polychromatophilia
C. Reticulocytosis
D. All of the above

A

9

Pathogenesis of autoimmune hemolytic anemia:

A. immune adherence of RBC to phagocytes mediated by the antibody
B. intravascular hemolysis
C. complement activation
D. A and C

D

10

Initial treatment of significant autoimmune hemolytic anemias consists of the following:
A. Glucocorticoids
B. Immunosuppressants
C. Splenectomy
D. All of the above

A

11

This finding of the following is highly atypical of Aplastic Anemia:
A. a.hepatosplenomegaly
B. b. bleeding
C. c. infection
D. anemia

A

12

The identification of leukemia subtypes are currently bases on:
A. exclusively on bone marrow morphology
B. a combination of marrow morphology and histochemical stains
C. a combination of marrow morphology, histochemical stains and a pattern of surface antigen expression
D. a combination of clinical presentation, morphology, histochemical stains, immunophenotyping, and cytogenetics

D

13

Disseminated Intravascular Coagulation in Acute Promyelocyte Leukemia is most commonly due to:
A. Gram positive bacterial sepsis
B. Release of thromboplastin from cytoplasmic granules of leukemic blasts
C. Hyperleukocytosis
D. None of the above

B

14

Achievement of true remission in CML requires:

A. Amelioration of leukocytosis and organomegaly
B. Amelioration of thrombocytosis
C. Destruction of Philadelphia chromosome positive cells
D. Control of Philadelphia chromosome positive test

C

15

Chloromas are:

A. Solid tumors composed of diffuse tissue infiltration by lymphoblasts
B. Solid tumors composed of diffuse tissue infiltration by myeloblasts
C. Should be surgically removed for optimal management
D. Are occasionally of greenish hue due to the absence of the enzyme peroxidase in the malignant cells

B

16

Which biochemical marker is considered a tumor marker for lymphoma?
A. Beta2 microglobulin
B. Carcinoembryonic antigen
C. CA-125
D. LDH

D

17

The most common cytogenetic abnormality in myelodysplastic syndrome (MDS) involves chromosome number
A. a.5
B. b.7
C. c.8
D. d.20

A

18

IDA anemia produces this type of anemia
A. Hypochromic, macrocytic
B. Normochromic, macrocytic
C. Hypochromic, microcytic
D. Normochromic, microcytic

C

19

Pregnant women should routinely be given iron because
A. The fetus needs iron
B. The mother has lost iron from her previous monthly menses
C. She will lose blood when she delivers
D. All of the above

D

20

The gold standard in the diagnosis of iron deficiency anemia is
A. serum iron
B. serum ferritin
C. total iron binding capacity
D. hemosiderin in bone marrow

D

21

During the first week of treatment with oral iron, which laboratory parameter should be taken?
A. hemoglobin
B. hematocrit
C. reticulocyte count
D. red cell indices

C

22

The duration of treatment with oral iron is usually six months because
A. the body’s iron stores have to be replenished
B. this will cover for the future occurrence of bleeding
C. this will facilitate more absorption of iron
D. all of the above

A

23

This food is rich in iron
A. fruits
B. vegetables
C. red meat
D. fish

C

24

A patient develops iron deficiency anemia after gastroduodenal bypass surgery:
A. because of poor iron absorption
B. because of poor iron utilization
C. because of poor iron intake
D. because of the decrease in the reticulo-endothelial system

A

25

Parenteral iron is given if:
A. rapid increase in hemoglobin is desired
B. malabsorption syndrom exists
C. the patient requested for it
D. rapid utilization of iron by the body

B

26

The most common single cause of iron deficiency in women is:
A. poor intake of iron
B. obesity
C. poor release of iron by the reticulo-endothelial system
D. menstrual blood loss

D

27

Chronic ingestion of non-steroidal anti inflammatory medication can cause iron deficieny anemia by:
A. interfering with iron transport
B. reducing the amount of total iron binding capacity
C. inducing occult GI bleeding
D. preventing iron incorporation in the red cells

C

28

A transfusion reaction that usually appears rapidly that may result in fever, shock or death is:
A. immediate hemolytic transfusion reaction
B. transfusion associated circulatory overload
C. allergic transfusion reaction
D. febrile non-hemolytic transfusion reaction

A

29

Type O is considered a universal donor because:
A. It doesn’t contain agglutinogens A and B
B. It doesn’t contain anti A and B antibodies
C. It is the most common bloodtype
D. It is easy to procure

A

30

The ff blood component should have a cross matching of the donor done before transfusion:
A. PRBC
B. Platelets
C. WBC
D. FFP

A