respiratory Flashcards

1
Q

surfactant secreting cells

A

Type II pneumocytes(cuboidal)

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2
Q

foreign body lung

A

right inferior lobe

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3
Q

methemoglobin

A

Fe3+(cyanide binding), Tx-methylene blue

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4
Q

pulmonary HTN pressure

A

> 25mmHg

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5
Q

primary pulmonary HTN gene

A

BMPR2(vascular smooth muscle proliferation)

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6
Q

virchows triad

A

stasis, hypercoagulability, endothelial damage

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7
Q

postpartum DIC

A

amniotic fluid embolism

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8
Q

fat embolism triad

A

hypoxemia, neuro, petechial rash

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9
Q

pre-death thrombus pathology

A

lines of zahn

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10
Q

low FEV/FVC ratio

A

obstructive lung disease(emphysema/bronchitis/asthma)

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11
Q

A1AT emphysema pathology

A

panacinar(smoking=centriacinar)

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12
Q

asthma pathology

A

curschmann spirals, charcot-leyden crystals

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13
Q

anthrax, silicon & asbestos lobes

A

anthrax&silicon-upper, asbestos-lower

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14
Q

trachial deviation causes

A

towards-atelectasis&pneumothorax, away-tension pneumo

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15
Q

adenocarcinoma gene

A

k-ras(most common in nonsmokers)

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16
Q

nasal polyps associations

A

cystic fibrosis, ASA-resistant asthma

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17
Q

nasopharyngeal carcinoma association

A

EBV(african kids chinese adults)

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18
Q

laryngeal papilloma association

A

HPV 6&11

19
Q

atypical pneumonia pathology

A

interstitial(viral)

20
Q

most common secondary pneumonia

A

staph aureus

21
Q

lobar pneumonia causes

A

strep p, klebsiella

22
Q

silver stain bug

A

legionella

23
Q

aspiration pneumonia bugs

A

bacteroides, fusobacterium, peptococcus (right lower lobe)

24
Q

primary TB

A

Ghon(calcified complex) lower lobe +hilar lymph nodes, asymptomatic

25
Q

secondary TB

A

apex+symptoms

26
Q

cytokine inducing fibrosis

A

tgf-beta

27
Q

coal pneumoconiosis association

A

rheumatoid arthritis

28
Q

plexiform lesions

A

long term pulmonary HTN

29
Q

ARDS pathology

A

hyaline membrane, leaked protein

30
Q

surfactant neonatal screening

A

Lecithin/sphingomyelin >2

31
Q

lung cancer Tx

A

small cell=chemo, non=surgery

32
Q

small cell cancer association

A

ADH, ACTH, Lambert Eaton

33
Q

squamous cell cancer association

A

PTHrP

34
Q

carcinoid test

A

chromogranin+(neuroendocrine)

35
Q

reid index >50%

A

bronchitis(excess mucous glands)

36
Q

A1AT allele

A

piZ=dysfunctional

37
Q

A1AT breathing

A

pursed lips(pink puffer)

38
Q

asthma associated cytokines

A

TH2- IL4(IgE),5(eosinophils),10(inhibit TH1)

39
Q

kartageners defect

A

dynein arm of cilia

40
Q

asthma challenge test

A

methacholine(muscarinic agonist)

41
Q

1st line for chronic asthma

A

corticosteroids(inactivate NF-kB, decrease TNFa)

42
Q

acute asthma Tx

A

albuterol(beta2agonisy)

43
Q

COPD Tx

A

tiotropium(muscarinic antagonist)

44
Q

aspirin induced asthma Tx

A

antileukotrienes(montelukast, zafirlukast)