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Board Associations > Pharm extra > Flashcards

Pharm extra Flashcards

1
Q

hyperTG Tx, MOA, SE

A

fibrates, LPL upregulation, myositis(+gallstones&liver)

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2
Q

low HDL Tx, MOA, SE

A

niacin, reduce VLDL secretion, flush/gout/acanthosis nigra

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3
Q

high LDL Tx, MOA, SE

A

HMGCoA(inh to mevalonate), rhabdo(+liver)

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4
Q

hypoglycemic toxicity DM drugs

A

2nd gen sulfonylureas(gli), insulins, amylin analog(lintide)

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5
Q

lactic acidosis toxicity DM drug

A

metformin

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6
Q

weight gain/HF toxicity DM drug/MOA

A

glitazones(PPARgamma-insulin sensitivity)

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7
Q

disulfiram-like RXN DM drugs

A

1st gen sulfonylureas(amides)

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8
Q

longish acting insulins

A

glargine, detemir, NPH

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9
Q

TNF-alpha inhibitors

A

infliximab, adalimumab, etanercept

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10
Q

HIT coag 2nd line

A

rudins-inhibit thrombin

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11
Q

ACS/stenting 2 options

A

ADP-R(grels/ticlodipine), GPIIb/3A Inh(abcmab/fIIbs)

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12
Q

claudication drugs

A

cilostozol, dipyridamole(phospho III inhibitors)

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13
Q

MTX vs 5FU toxicity

A

leucovorin vs thymidine rescue

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14
Q

cyclophosphamide MOA, SE+Tx

A

link guanine N-7, hemorrhagic cystitis-prevent w/mesna

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15
Q

pulmonary HTN Tx, MOA

A

bosenten-endothelin1 inhibit

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16
Q

reduce uterine contractions, MOA

A

terbutaline-beta2-agonist

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17
Q

clomiphene use&MOA

A

infertility/PCOS, partial agonist SERM

18
Q

emergent glaucoma Tx

A

pilocarpine-increase outflow contracting ciliary muscle

19
Q

random opiods

A

meperidene, diphenoxylate, dextromethorphan, butorphanol

20
Q

stevens-johnson drugs

A

carbamazepine, ethosuxamide, phenytoin, lamotrigine

21
Q

barbiturates(include thiopental) vs benzos MOA

A

increase duration of Cl- channel opening vs increasing frequency= increase in GABA in both

22
Q

NMDA block anesthesia

A

ketamine(PCP analog)

23
Q

succinylcholine MOA, OD Tx, similar agents

A

sustained NM depolarization, ACh-esterase inh(neostigmine) but only in phase 2. curiums

24
Q

dantrolene use

A

malignant hyperthermia+neuroleptic malignant syndrome

25
Q

benztropine, selegine/capones, amantadine, ldopa, bromocriptine/pramiprexole/ropinarole use+MOA

A

parkinsons-antiM(tremor), MAOB inh(less dopa degraded), inc dopa release, dopa, dopa agonists

26
Q

reserpine/tetrabenzine, haloperidol use+MOA

A

huntingtons-inhibit VMAT(limit dopa release), dopaR ant

27
Q

sumatriptan contraindication

A

CAD/prinzmetal(causes vasospasm)

28
Q

memantine, donepezil/galantamine/rivastigmine use+MOA

A

alzheimers-NMDA antagonist, ACh esterase inhibitors

29
Q

alcohol withdrawal Tx

A

benzos(pams/lams/chlordiazepoxide)

30
Q

trifluoperazine, fluphenazine, haloperidol MOA&SE(TFH)

A

D2 block high potency-EPS(kinesias)H=NMS+tardive

31
Q

thioridazine, chlorpromazine SE

A

low potency-alpha/H/cholinergic SE, reTinal, Corneal

32
Q

weight gain drugs+other SE

A

clozapine/olanzapine-atypicals, c=agranulocyte+seizure

33
Q

long QT drug+other atypicals

A

ziprasidone(quietapine, risperadone, aripiprazole)

34
Q

heart block drug, other SE

A

lithium-tremor, hypothyroid, polyuria, ebsteins in kids

35
Q

anxiety med for alcoholics, MOA

A

buspirone-5HT1A

36
Q

iptyline/ipramine, doxepin, amoxepine SE+Tx

A

3Cs(cardio/convulsion/coma), NaHCO3

37
Q

seratonin sydrome causes, Tx

A

SSRI, SNRI, TCA, MAO, cyproheptadine

38
Q

venlafaxine, duloxetine MOA+SE

A

SNRI-high BP+stimulant effects

39
Q

MAO inhibitors+SE

A

MAO Takes Pride In Shanghai-Tranylcypromine, phenelzine, isocarboxazid, selegine, HTN crises

40
Q

mirtazapine, maprotiline, trazodone MOAs/SE

A

a2+5HT2/3 antagonist-weight gain/sedation, NERI-hypotension, serotonin reuptake-PRIAPISM

Board Associations (22 decks)

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