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Board Associations > Repro > Flashcards

Repro Flashcards

1
Q

teratogenic period

A

weeks 3-8

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2
Q

conyloma association

A

HPV 6&11

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3
Q

koilocytic change

A

HPV

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4
Q

HPV 16, 18 lesions

A

dysplasia-intraepithelial neoplasia, progress to carcinoma

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5
Q

thin white vulvar skin vs thick white

A

lichen sclerosis, lichen simplex chronicus (rule out carcinoma)

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6
Q

paget’s disease vs. melanoma labs

A

paget=PAS+ keratin+ S100-, melanoma opposite

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7
Q

female reproductive tract derivation

A

mullarian duct(paramesonephric)

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8
Q

vaginal adenosis association

A

DES in pregnancy(persistent columnar epithelium) then possible clear cell adenoma

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9
Q

grape-like mass

A

rhabdomyosarcoma(desmin&myogenin+)

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10
Q

vaginal cancer spread

A

lower 1/3=inguinal, upper 2/3=iliac

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11
Q

HPV virus type& high risk protein targets

A

DNA, e6=p53, e7=Rb

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12
Q

complication of cervical cancer

A

bladder invasion

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13
Q

asherman syndrome lesion

A

post procedural uterine adhesions(loss of basalis)

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14
Q

endometrial polyp cause

A

tamoxifen

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15
Q

unopposed estrogen causes

A

endometrial hyperplasia(possibly endometroid carcinoma)

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16
Q

sporadic endometrial cancer lesion

A

p53, serous papillae on atrophic endometrium

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17
Q

psammoma body causes

A

papillary cancer thyroid, papillary sporadic endometrial, meningioma, mesothelioma

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18
Q

leiomyoma vs leiomyosarcoma

A

multiple white whorled vs. one hemorrhaging

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19
Q

endometriosis common lesions

A

ovary chocolate cysts, uterus/pouch of douglas/fallopian, soft tissue gunpowder lesions

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20
Q

theca cell function

A

LH causes androgen production

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21
Q

granulosa cell function

A

FSH converts androgen to estrogen(egg maturation)

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22
Q

corpus luteum function

A

secrete progesterone

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23
Q

polycystic ovarian syndrome

A

increased LH(LH:FSH>2) associated to T2DM(fat)

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24
Q

BRCA1 reproductive tumors

A

serous carcinoma of ovary/fallopian tubes

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25
Q

brenner tumor characteristic

A

urothelium cells

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26
Q

most common germ cell tumor in females

A

cystic teratoma

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27
Q

most common malignant germ cell tumor

A

dysgerminoma(looks like egg, high LDH)

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28
Q

endodermal sinus tumor pathology

A

schiller-duvall bodies, high AFP, mimics yolk sac(most common in kids)

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29
Q

choriocarcinoma lab

A

high bHCG(small and hemorrhagic fast spread)

30
Q

granulosa-theca cell tumor lab

A

excess estrogen

31
Q

reinke crystals(pink) tumor type

A

leydig

32
Q

fibroma association

A

pleural effusion, ascites(Meigs syndrome)

33
Q

bilateral krukenberg tumor association

A

mucinous tumor(especially gastric carcinoma)

34
Q

pseudomyxoma peritonii lesions

A

primary appendix tumor+mucinous ovarian

35
Q

ectopic pregnancy risk factors

A

PID, endometriosis(scarring)

36
Q

preeclampsia triad

A

HTN, proteinuria, edema(seizures=ecclampsia-deliver)

37
Q

HELLP

A

hemolysis elevated liver enzymes low platelets(liver microangiopathy is cause)

38
Q

passing grapelike masses

A

hydatidaform mole (snowstorm US)

39
Q

partial mole features

A

69(two sperm+mom)+fetal tissue

40
Q

complete mole features

A

46(just two sperm) all villi edematous, high risk

41
Q

hypospadias embryology

A

failure of urethral folds to close

42
Q

epispadias embryology/association

A

abnormal genital tubercle positioning, bladder exstrophy

43
Q

lymphogranuloma venerum bug&pathology

A

Chlamydia L1-3(obligate intra), necrotizing lymph nodes

44
Q

cryptorchidism association

A

sterility, seminomas

45
Q

orchitis/prostatitis bugs

A

chlamydia/gonorrhea, ecoli/pseudamonas adults, mumps

46
Q

hyrdocele fluid location

A

tunica vaginalis(improper closure of processus vaginalis)

47
Q

seminoma pathology

A

large clear cells(good prognosis) Tx-radiotherapy

48
Q

embyonal pathology

A

necrotic/hemorrhagic primitive cells(chemo-sometimes differentiates) high AFP/bHCG sometimes

49
Q

most common kids tumor+labs

A

yolk sac, high AFP, schiller duval(glomerulus like)

50
Q

choriocarcinoma lab/side effects

A

high bHCG-gynecomastia/hyperthyroid

51
Q

teratoma male vs female

A

benign in F, malignant in M

52
Q

most common testicular mass cause in old men

A

diffuse large Bcell lymphoma

53
Q

BPH Tx

A

a1 antagonist/5a reductase

54
Q

most common cancer in men

A

prostatic adenocarcinoma(posterior periphery) PSA>10

55
Q

cancer NOT to biopsy in men

A

testicular-most malignant

56
Q

prostate cancer spread

A

lumbar-osteoblastic metastastes(Tx-androgen inh/GnRH analog)

57
Q

periductal mastitis association

A

smoking(vit A deficiency), nipple retraction

58
Q

green-brown nipple discharge

A

mammary duct ectasia

59
Q

normal breast change

A

fibrocystic-blue dome cysts(apocrine metaplasia NO cancer risk)

60
Q

bloody nipple discharge

A

intraductal papilloma papillary carcinoma(no myoepithelial)

61
Q

most common mass

A

fibroadenoma-change with estrogen

62
Q

comedo ductal CIS

A

central necrosis/calcification(pagets if reaches nipple)

63
Q

BRCA1 lesion

A

medullary carcinoma

64
Q

lobular carcinoma in situ pathology

A

lacking E cadherin(risk factor, Tx-tamoxifen)

65
Q

Tx-response for breast cancer based on

A

Estrogen/progesterone(tamoxifen), Her2Neu(trastuzamab) receptors

66
Q

male breast cancer

A

BRCA2/klinefelters(ductal carcinoma)

67
Q

gynecomastia causes

A

spirinolactone, digitalis, cimetadine, alcohol, ketaconazole

68
Q

GnRH analog drug

A

leuprolide

69
Q

BPH Tx&MOA

A

finasteride-5-alpha reductase inhibitor or tamsulosin-a1ant

70
Q

ketoconazole use&MOA

A

PCOS hirsuitism-inhibit 17,20 desmolase(steroid synthesis)

71
Q

abortificants

A

mifepristone&misoprostol(PGE1)

Board Associations (22 decks)

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