22 Social influences ln liver function Flashcards
(16 cards)
How is BMI calculated?
Weight/Height^2
What are the disadvantages of BMI?
Does not distinguish between mass due to body fat and mass due to muscle
What is a better predictor for risk of diabetes and CV disease?
Waist circumference and BMI
What factors increase risk of obesity?
Balance between energy intake and use, high intake of high fat/high sugar foods, high alcohol intake, lack of physical activity, medical conditions, genetic variability
What genetic conditions increase risk of obesity?
Untreated hypothyroidism
What is non-alcoholic fatty liver disease?
Excess fat in the liver, affecting its function
What is steatosis?
Benign fatty liver (fat accumulation in liver cells)
What is NASH short for?
Non-alcoholic steato hepatitis
What occurs in fibrosis of the liver?
Scar tissue collagen and extra cellular matrix proteins are deposited in response to injury
What occurs in cirrhosis of the liver?
Accumulation of scar tissue blocks blood flow and affects function
What is hepatocellular carcinoma?
Primary malignancy of the liver
What are the symptoms of NASH?
Fatigue, loss of appetite, abdominal discomfort, jaundice and itch
What is diet and obesity related liver disease caused by?
High calorie intake, trans/saturated fats, cholesterol, fructose-sweetened drinks which all increase visceral adiposity and stimulate hepatic lipid accumulation
What is the management for NASH?
Weight loss
When does alcoholic liver disease increase risk of death?
If intake is >25g of alcohol a day
How does alcoholic intake influence liver function?
Fatty liver, alcoholic hepatitis, cirrhosis, decompensated liver failure, pancreatitis, oesophageal varices and mortality rate
