22.2 Neonatal Jaundice Flashcards Preview

Sydney Child Health Program > 22.2 Neonatal Jaundice > Flashcards

Flashcards in 22.2 Neonatal Jaundice Deck (15):
1

why neonate have likely jaundice?

-shorter red cell survival
-decreased metabolism from liver
-increased enterohepatic circulation, less stool

2

definition of hyperbilirubinaemia?

unconjugated at >205umol/l
Preterm: >255umol/l

3

causes of unconjugated hyperbilirubinaemia?

-increased production
-haematoma
-decreased conjugation
-increased enterohepatic circulation

4

physiological jaundice happens when?

>24 hours

5

breast milk jaundice is?

delayed milk production, relative calorie deprivation

6

causes of conjugated jaundice?

-hepatitis
-biliary atresia
-A1 antitrypsin deficiency
-total parenteral nutrution

7

prolonged jaundice need to exclude two important causes?

-obstructive jaundice
-hypothyroidism

8

Kernicterus is?

bilirubin staining in brain, free unconjugated bilirubin crosses BBB

9

risk of kernicterus increased when?

premature
low albumin
rapid rise
hypoxia, sepsis, hypoglyc

10

risk groups for neonatal jaundice?

maternal: DMII
perinatal
TORCH infections

11

why asian background more likely to have neonatal jaundice?

higher incidence of G6PD deficiency

12

investigations for neonatal jaundice?

-bilirubin levels: fractions
-haemolysis: BLOOD FILM
-infection
-metabolic

13

treatment for jaundice?

phototherapy
IVG
exchange transfusion

14

indications for exchange transfusion?

-ABO/incompatibilities and bili exceeds 340umol/l
-preterm infant and exceeds 340umol/l

15

transcutaneous phototherapy use in what setting?

-lower levels
-NOT after you've started phototherapy

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