23.3 Toxicology Flashcards Preview

Sydney Child Health Program > 23.3 Toxicology > Flashcards

Flashcards in 23.3 Toxicology Deck (41):
1

one pill can kill, dangerous ingestions?

amphetamines
beta blockers
CCBs
digoxin
opioids
sulphonylureas
TCA

2

pesticides which ones?

paraquat: 1 mouthful

3

what is the acronym DEAD?

decontamination
elimination
antidotes
deposition

4

after ABCs what to watch out for?

full neuro exam
urinary retnetion
skin
bowel sounds

5

which drug levels are helpful?

paracetamol
if indicated
phenytoin
carbamazepine
valproate
phenobarbitone

6

anticholinergic toxidromes?

blind as a bat
mad as a hatter
red as a beet
hot as a hare
dry as a bone
bowel and bladder lose their tone, Retention
heart runs alone

7

anticholinergic toxidromes, which causes agitated delirium?

plants

8

pills that cause anticholinergic toxidromes present?

usually partially sedated

9

anticholinergic toxidromes pupils?

dilated

10

anticholinergic toxidromes bladder?

retention usually, IDC can be beneficial

11

common causes of anticholinergic toxidromes?

anti-histamines
TCA
phenothiazine
plants: datura, brugmansia
benztropine (for dystonia)

12

Cholinergic crisis classically think?

secretions
organophosphates

13

Cholinergic crisis acrynoym for secretions?

DUMBELS

diarrhoea
urination
miosis
bradycardia, bronchorrea
emesis
lacrimation
salivation

14

sympathomimetic syndrome is?

hot, sweaty patient
hypertension
tachy
dilated pupils
agitation
sweating
hyperthermia - treat

15

sympathomimetic toxidrome causes?

-cocaine
-methamphetamines
-ecstasy, MDMA
-synthetic 'marijuana'

16

serotonin toxicity key examination findings?

hyperreflexia, clonus

sweating
hypertension
dilated pupils

17

serotonin toxicity causes?

usualyl a combo of:

SSRIs/SNRIs
MAOIs
tCAs
tramadol
opiates
amphetamines/MDMA

18

opioids toxidrome

-respiratory depression
-sedation
-pinpoint pupils

19

opioids toxidrome when give naloxone indication?

the resp rate and the sats

20

supportive care of poisoned patient sedation ?

benzodiazepines

21

supportive care of poisoned patient seizures?

-IV benzos
-not phenytoin

22

supportive care of poisoned patient body temp?

warm
cool control quickly

23

supportive care of poisoned patient renal function?

hydration
dialysis

24

GI decontamination main use?

activated charcoal

25

why not GI decontamination with vomiting?

tears and ruptures

26

how much GI decontamination activated carcoal measurement?

1g/kg
mix with water, orally or NGT

27

indications for charcoal?

-within 1 hour of ingestion, or if slow release
-cooperative patient
-alert and protected airway

28

contraindications for charcoal?

-Metals: LI, K, alcohols, hydrocarbons, corrosives
""MACH""
-low GCS
-ileus

29

whole bowel irrigation indications?

-lots of slow release
-body packers
-metals

30

enhanced elimination, 3 kinds?

-multi dose activated charcoal
-urinary alkalinisation (ion trapping, mainly for aspirin)
-haemodialysis

31

when to use enhanced elimination?

-methanol/antifreeze
-lithium
-aspirin - severe only
-theophylline
-alproic acid severe
-carbamazepine

32

what is toxic dose of paracetamol?

>200mg/kg

33

paracetamol when to take the measurement?

4 hours post to get peak

34

paracetamol antidote?

NAC

35

redback spider bite treatment?

mainly analgesia
antivenom rare

36

funnelweb spider bites?

-most uncommon bite
-needs ANTIVENOM
-look at tongue for fasciculation (can't fake it)

37

brown snake characteristic of bite?

-early collapse
-consumptive -coagulopathy
-most common cause of death

38

Do's for envenomation?

remove from danger
immobilise
keep still
apply pressure bandage

39

dangers of antivenom?

equine-derived, allergenic, can get anaphylaxis

40

treatment of box jelly fish?

remove tentacles, vinegar
anti-venom available

41

bluebottle sting treatment?

hot water without burning?
put both feet in the bucket of water as control to prevent burns

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