Kreb Cycle Flashcards

0
Q

Step 2

Citrate is

A

Isomerized by

Transfer of OH group to yield

Isocitrate

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1
Q

Step 1

Acetyl group is transferred from

A

Acetyl-SCoA

To

Oxaloacetate

Produced in step 8

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2
Q

Step 3

Isocitrate loses

A

CO2
And is

Oxidized to yield
Alpha- ketoglutarate

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3
Q

Step 4

Alpha-ketoglutarate
Reacts with

A

Coenzyme A
And loses
CO2 to yield
Succinyl-SCoA

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4
Q

Step 5

Succinyl-CoA is set

A
Free to give
Succinate
Plus
CoA 
In a reaction coupled with
ATP formation
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5
Q

Step 6

Two hydrogens

A

Are removed from
Succinate
To yield
Fumarate

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6
Q

Step 7

Addition of water

A

To the double bond of
Fumarate yields
Malate

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7
Q

Step 8

The cycle of reactions

A

Is completed by

Oxidation of malate to
Regenerate
Oxaloacetate

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8
Q

Acetyl CoA available from the

A

Breakdown of
Carbohydrates
Lipids
Amino acids

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9
Q

Acetyl CoA is the

A

Fuel of the citric acid cycle

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10
Q

The operation of the cycle requires a supply of the

A

Oxidizing agents

NAD and FAD

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11
Q

The cycle is dependent on

A

Reactions of the electron transport chain

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12
Q

the electron transport chain supplys

A

The necessary
NAD
FAD

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13
Q

In each turn of the cycle

A

Acetyl CoA enters and two fully oxidized carbon molecules leave as CO2

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14
Q

Acetyl-CoA

From the

A

Glycolytic pathway
or
From fatty acid catabolism

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15
Q

Three molecules of

A

NAD

16
Q

One molecule of

A

FAD

17
Q

Three molecules of NAD and one molecule of FAD are

A

Reduced

18
Q

One molecule of GTP

A

Is generated in a

Substrate level phosphorylation reaction

19
Q

GTP

A

Interconvertible with ATP