CNS Flashcards
The peripheral nervous system is made up of which branches?
- The Somatic Nervous system
- The Autonomic nervous system
- The Enteric nervous system
What is the central nervous system made up of?
The brain and spinal cord
What does the somatic nervous system control?
Skeletal muscle
What does the Autonomic nervous system control?
- Smooth muscle
- Cardiac Muscle
- Glands
- Adipose tissue
What does the Enteric nervous system control?
Smooth muscle, glands and endocrine cells of the GI tract.
What nerves is the peripheral nervous system made up of ?
Cranial and spinal nerves that contain both motor and sensory fibres
What is the function of the peripheral nervous system?
Connects the CNS to muscles, glands and all sensory receptors.
What neurons is the Somatic (voluntary) nervous system made up of?
- Neurons from cutaneous and special sensory receptors to the CNS
- Motor neurons to skeletal muscle tissue
What neurons is the Autonomic nervous system comprised of ?
- Sensory neurons from visceral organs to CNS
* Motor neurons to smooth and cardiac muscle and glands.
What effect does the sympathetic nervous system have on the heart?
Speed up heart rate
What effect does the parasympathetic nervous system have on heart?
Slows down heart rate
What function does the Enteric nervous system have?
- Involuntary sensory and motor neurons control the GI tract
* neurons function independently of the ANS and the CNS
What is a neuron?
• functional unit of the nervous system • capacity to produce an action potential
What structures can be found in a neuronal cell body?
- Single nucleus
- prominent nucleolus
- Nissl bodies
- Rough ER and Ribosomes
- Neurofilaments (shape and support)
- Microtubules (move material inside cell)
- Lipofuscin pigment clumps
What cell processes do neurons have ?
Dendrites and Axons
What is the function of Dendrites?
Conduct impulses towards the cell body
What are the characteristics of dendrites?
- Short
- Highly branched
- Unmyelinated
- Surfaces are specialized for contact with other neurons
- contains neurofibrils and Nissl bodies
What function do axons perform?
They conduct impulses away from the cell body
What are the characteristics of axons?
- Long, thin cylindrical processes
- collaterals end in fine processes called axon terminals
- synaptic end bulbs contain vesicles filled with neurotransmitters
Where does and axon arise from?
The axon hillock
Where do impulses arise from in an axon?
The initial segment (trigger zone)
Sensory neurons are also called what?
Afferent neurons
Motor neurons are also called what ?
Efferent neurons
Interneurons are also called what?
Association neurons
What is the function of sensory neurons?
Transport information from skin, muscles, joints, sense organs and viscera to the CNS
What is the function of motor neurons ?
Send motor information to muscles and glands
What is the function of interneurons?
Connect sensory to motor neurons
What percentage of neurons do interneurons comprise ?
90%
How are neurons classified ?
• based on the number of nerve processes on the cell body
What are the characteristics of mulitipolar neurons?
- Several dentrites and one axon
* most common neuronal cell type
What are the characteristics of bipolar neurons?
- One main dendrite and one axon
* Found in the retina, inner ear and olfactory
What are the characteristics of unipolar neurons?
- One process only
- Develops from a bipolar neuron
- Always sensory neurons
How many types of interneurons are there?
2
Name the two types of interneuron cells.
- Purkinje cells
* Pyramidal cells
Name the 6 types of neuroglial cells.
- Astrocytes
- Oligodendrocytes
- Microglia
- Ependymal cells
- Schwann cells
- Satellite cells
What are the four types of Neuroglial cells found in the CNS.
- Astrocytes
- Oligodendrocytes
- microglia
- Ependymal
What are the two types of Neuroglial cells found in the PNS ?
- Schwann cells
* Satellite cells
What are the characteristics of Neuroglial cells?
- Smaller than neurons
- 50 x more numerous
- can divide - rapid mitosis in tumour formation (gliomas)
What cells make up half of the volume of the CNS.
Neuroglia
What cells are Gliomas formed from?
Neuroglia
What is the most common glial cell type ?
oligodendrocyctes
What are microglia?
Small cells found near blood vessels in the CNS
What is the function of Microglia?
• phagocytic
Microglia are cells which are formed from cells which also gave rise to which two cells types?
Macrophages and monocytes
What are Satellite cells?
Flat cells surrounding neuronal cell bodies in peripheral ganglia
What is the function of Satellite cells?
Support neurons in the PNS ganglia
What do Schwann cells do?
They encircle PNS axons and produces part of the myelin sheath surrounding an axon in the PNS
Where is grey and white matter found in the spinal cord?
The grey matter is found in the central H shaped inner core and is surrounded by white matter
Where is grey matter found in the brain?
- thin outer layer covering surface of brain
* clusters called nuclei inside the CNS
Name the different types of neuronal circuit.
- Diverging
- Converging
- Reverberating
- Parallel-after-discharge
How does a diverging neuronal circuit behave?
A single cell stimulates many others
How does a converging neuronal circuit behave!
One cell is stimulated by many others
How does a reverberating neuronal circuit behave?
Impulses from later cells repeatedly stimulate early cells in the circuit (short term memory)
How do parallel-after-discharge circuits behave?
Single cell stimulates a group of cells that all stimulate a common post-synaptic cell (maths problems)
What are the functions of Dendrites?
- receive stimuli through activation of chemically or mechanically gated ion channels
- In Sensory neurons produce generator or receptor potentials
- In Motor neurons and association neurons produces excitatory and inhibitory post-synaptic potentials
What is the function of the neuronal cell body?
- Receive stimuli
* Produces EPSPs and IPSPs through activation of chemically or mechanically gated ion channels
What is the function of the junction of the axon hillock and the initial segment of the axon
- Trigger zone
* Integrates EPSPs and IPSPs and if sum is depolarisation the reaches threshold initiates an action potential
What is the function of the axon?
Propogates nerve impulses from initial segment (or from dendrites in sensory neurons) to axon terminals
Does the amplitude of an action potential change as it propagates along an axon ?
No
What happens at axon terminals and synaptic end bulbs?
Inflow of Ca2+ caused by depolarising phase of nerve impulse cause neurotransmitter release by exocytosis of synaptic vesicles
What types of ion channels are found in neuronal cell dendrites and the cell body?
Chemically gated ion channels