26 - IBD Flashcards Preview

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Flashcards in 26 - IBD Deck (6)
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1

IBD - EPI

18 - 24, then 70+
Big cities
America
Genetic (monozygotic twins 60%, children 10%, siblings 10%)

2

Crohn's Disease

Patchy inflammation
Mouth to anus involvement
Transmural inflammation
Fistulas and strictures common
Risk of cancer
Extraintestinal mainfestations
Higher risk for smokers
Can have granulomas

3

Ulcerative Colitis

Continuous inflammation
Generally affects the colon
Mucosal inflammation
Fistulas and strictures seldom
Risk of colorectal cancer
Extraintestinal manifestations
Lower risk for smokers
Granulomas uncommon

4

Ulcerative Colitis - Practical

Always bleeds
Only involves the colon
Protected by smoking

5

Extraintestinal Mainfestations of IBD

Ocular disorders
Aphthous stomatitis
Ankylosing spondylitis
Nephrolithiasis
Sacroileitis
Thromboembolic complications
Skin disorders
Peripheral arthritis
Primary sclerosing cholangitis
Hepatobiliary disorders

6

Venn Diagram of IBD

Luminal Antigens
Genetic Susceptibility
Environmental Triggers