26 - IBD Flashcards

1
Q

IBD - EPI

A

18 - 24, then 70+
Big cities
America
Genetic (monozygotic twins 60%, children 10%, siblings 10%)

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2
Q

Crohn’s Disease

A
Patchy inflammation
Mouth to anus involvement
Transmural inflammation
Fistulas and strictures common
Risk of cancer
Extraintestinal mainfestations
Higher risk for smokers
Can have granulomas
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3
Q

Ulcerative Colitis

A
Continuous inflammation
Generally affects the colon
Mucosal inflammation
Fistulas and strictures seldom
Risk of colorectal cancer
Extraintestinal manifestations
Lower risk for smokers
Granulomas uncommon
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4
Q

Ulcerative Colitis - Practical

A

Always bleeds
Only involves the colon
Protected by smoking

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5
Q

Extraintestinal Mainfestations of IBD

A
Ocular disorders
Aphthous stomatitis
Ankylosing spondylitis
Nephrolithiasis
Sacroileitis
Thromboembolic complications
Skin disorders
Peripheral arthritis
Primary sclerosing cholangitis
Hepatobiliary disorders
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6
Q

Venn Diagram of IBD

A

Luminal Antigens
Genetic Susceptibility
Environmental Triggers

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