12 - The National Strategy on the Prevention of HBV, HCV andHCC Flashcards
(18 cards)
How many people worldwide are living with viral hepatitis?
1 in 12
HBV and HCV cause what percentage of cirrhosis worldwide?
57%
HBV and HCV cause what percentage of HCC worldwide?
78%
What is the leading infectious cause of death in the USA?
Viral hepatitis
How much money per year is spent on liver disease?
$5 - 10 billion
Goals for attacking this shit
Increase proportion aware of their HBV status to 66%
Increase proportion aware of their HCV status to 66%
Reduce new HCV infections by 25%
Eliminate mother-to-child HBV transmisison
Prevention strategies
Immunization
Screening
Behavioral Counseling
Chemoprevention
Levels of disease prevention
Primary:
Prevents disease from occurring
Vaccination
Secondary:
Catch early, halt progression
Screening for cancers
Tertiary:
Prevent deterioration
Eliminating allergens from asthma patients
HBV Vaccine
Introduced in 1982
Safe & >90% effective
Recommended for newborns of HBV-infected mothers
Universally for infants in the US since 1991
Adolescents
High risk groups (IVDU, dialysis, etc)
Anyone with chronic liver disease
HBV Screening
HBsAG
Recommended for those at high risk
HBV Chemoprevention
Post-exposure Prophylaxis
Hepatitis B Immune Globulin (HBIG) AND HBV Vaccine
Hepatocellular Carcinoma
5th most common cancer worldwide
3rd most common cause of cancer death worldwide
Super closely linked to HBV
INCREASING prevalence worldwide
HCC Prevention Guidelines
Ultrasound every 6 months Blood Test: Alpha Fetoprotein (AFP) Glycoprotein elevated in patients with HCC Not good for screening Good for following course
HCC Screening
Actually prevented HCC-related mortality!!!!
HCC Screening Test
We aren’t using it nearly enough
Toxins related to HCC
Aflatoxin (mycotoxin contaminating corn, soybeans, peanuts)
Contaminated drinking water (pond shit)
HCC - Chemoprevention
Antiviral Treatment (HBV & HCV)
Increased Coffee Consumption
Protects against HCC
