28 Overview of Respiratory Function Flashcards

1
Q

Equation for compliance?

A

Compliance= Delta V/ Delta P

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2
Q

O2 is most important for regulating ___

CO2 is most important for regulating____

A
  • Heart circulation, peripheral (emergency) pulmonary chemoreceptors
  • Brain circulation, central pulmonary chemoreceptors
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3
Q

Pulmonary drive has what 3 components?

A
  • Pattern generator
  • Integrator
  • Motor output
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4
Q

What is normal PaCO2?

A

40 mmHg. Maintained very powerfully.

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5
Q

Pulmonary diseases usually affect drive, bellows, or diffusion?

A

Bellows (even abdominal distension!)

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6
Q

Pulmonary Function Testing tests drive, bellows, or diffusion? Another name for this testing is what?

A
  • Bellows (Resistance and Compliance)

- Spirometry

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7
Q

Equation for resistance?

A

R= Delta P/Flow (Think electrical V=I*R)

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8
Q

Asthma is what kind of pulmonary problem?

A

high resistance

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9
Q

Emphysema is what kind of pulmonary problem?

A

High compliance (air is not forced out of lungs) and somewhat high resistance

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10
Q

Fibrosis and pulmonary edema are what kind of pulmonary problem?

A

Low compliance (air is hard to suck into lungs)

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11
Q

T/F increased compliance decreases the work of breathing?

A

False. Since last breath doesn’t go all the way out, it is harder to suck next breath in due to 1) mechanical disadvantage and 2) Higher alveolar pressure at end-expiration “AutoPEEP”

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12
Q

Where in the body is O2 concentration the lowest?

A

Mitochondria

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13
Q

What is the main transport system for CO2?

A

Bicarbonate ion, thru chloride shift. (Cl into RBC, HCO3 out)

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14
Q

T/F The functional residual capacity can be expired when desired?

A

False. Only part of it can.

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15
Q

FRC is?

A

Functional Residual Capacity

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16
Q

TLC is?

A

Total Lung Capacity

17
Q

RV is?

A

Residual volume. Vol. left after a forced exhale

18
Q

IC is?

A

Inspiratory capacity (from a tidal exhale)

19
Q

ERV is?

A

Expiratory Reserve Volume (dif of tidal exhale versus forced exhale)

20
Q

VC is?

A

Vital capacity. Total forced breath from in to out.

21
Q

TV is?

A

Tidal volume

22
Q

At what point does the chest wall pull balance the lung pull?

A

FRC

23
Q

FEV1 is most useful in measuring resistance or compliance?

A

Resistance

24
Q

What tests are done to measure how well gas exchange is occurring?

A

Oximetry and blood gas analysis

25
Q

What are secondary functions of the lungs?

A
  • Control H+ levels
  • Heat loss
  • Immune surveillance. (Rich in antimicrobial peptides and cells)
  • Inactivation/activation of bio-active substances made elsewhere.