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GI and Nutrition > 3.3.2 Pathology of Liver Injury II > Flashcards

3.3.2 Pathology of Liver Injury II Flashcards

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1
Q

What are these? What are they found in?

A

Microabcesses; CMV hepatitis

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2
Q

Condition?

A

Chronic Hep

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3
Q

Describe the type of virus, viral family, route of transmission, mean incubation period, frequency of chronic liver dz, diagnosis of the subtypes of standard hepatitis.

A
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4
Q

These are used to measure severity of what?

A

Chronic Hep C

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5
Q

When is CMV hepatitis most common?

A

After renal and liver transplant (immunocompromised)

Must screen for CMV

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6
Q

Condition?

A

Acute Hepatitis

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7
Q

What condition?

A

Chronic Hep B

(Ground Glass Appearance)

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8
Q

What are these? what are they found in?

A

“owl eye” inclusions; CMV hepatitis

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9
Q

Type of Hep?

A

Hep C

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10
Q

What is antigen targeted in the hep B vaccine?

A

HBsAg (surface antigen)

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11
Q

Three conditions that result from non-alcoholic fatty liver dz?

A

steatosis, steatohepatitis, fibrosis

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12
Q

Condition?

A

Alcohol-induced liver dz

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13
Q

Condition?

A

Alcoholic hepatitis

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14
Q

Type of Hep?

A

Hep D

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15
Q

What is the end stage outcome of chronic hepatitis?

A

Cirrhosis

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16
Q

What are the diagnostic criteria for autoimmune hepatitis?

A
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17
Q

What are the clinical signs of cirrhosis?

A
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18
Q

What is the abundant cell type? Condition?

A

Plasma Cell; AI hepatitis

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19
Q

Condition?

A

Hepatic steatosis

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20
Q

Condition?

A

Non-alcoholic fatty liver dz

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21
Q

Condition?

A

Autoimmune hepatitis

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22
Q

What are the four different presentations of hepatitis?

A
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23
Q

What is the common result of acute hep? chronic hep? fulminant hep?

A
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24
Q

What type of hepatitis?

25
What type of patients are commonly affected by herpes hepatitis?
Immunocompromised pts
26
What are the three conditions caused by alcohol-induced liver dz?
Steatosis, hepatitis, cirrhosis
27
What are the 3 M's of herpes hepatitis?
Multinucleation, Molding, Margination
28
Where are the dominant features in acute viral hepatitis?
Lobular/acinus
29
Type of Hep?
Hep B
30
What are some of the features of the two stages of autoimmune hepatitis?
31
What is seen on biopsy of CMV hepatitis?
Focal hepatocyte necrosis, microabcesses, and ocasssional sinusoidal lymphocytic infiltrate, "owl's eye" intranuclear inclusion
32
Condition?
Alcoholic hepatitis
33
Persitant inflammatory reaction of the liver with more than 6 months of clinical signs and symptoms?
Chronic hep
34
What dz process is shown below?
Confluent necrosis
35
What is used to treat/reduce inflammation in AI hepatitis?
Steriods
36
Type of Hep?
Hep C
37
This the dream treatment for chronic hep C. What is it?
Harvoni
38
Type of Hep?
Hep B
39
What dz process is shown below?
Interface Hep
40
Left? Right?
Left: Acute hep Right: Normal
41
Type of Hep?
Hep C
42
Condition?
Alcohol-induced liver dz
43
What dz process is shown below?
Apoptosis and lobular inflammation
44
Condition?
Acetominophen OD
45
Which types of acute hepatitis commonly progress to chronic?
B, C, D
46
Condition?
Hepatic Steatosis
47
What dz process is shown below?
Interface inflammation
48
Can affect both immunocompetent and immunocompromised patients. Causes diffuse sinusoidal lymphocytic infiltrate "string of pearls" with varying degrees of portal inflammation.
EBV hepatitis
49
What are some of the histologic characteristics of hepatic herpes?
Patchy coagulative necrosis, no particular zonal distribution ## Footnote **Eosinophilic intranuclear inclusions**
50
This type of hepatitis: Vaccine; no carrier or chronic state; spread through fecal-oral contamination; endemic in countries with substandard sanitation; sporadic, febrile illness with jaundice fatigue, loss of appetite
Hep A
51
What dz process is shown below?
Portal inflammation
52
Symptoms and clinical presentation of fulminant hep.
53
Condition?
Fulminant Hep
54
What type of cell is increased in AI hepatitis?
Plasma cells
55
Condition?
Chronic Hep C
56
Type of Hep?
Hep E
57
What some of the viral cause of hepatitis?
EBV, CMV, Yellow fever, Herpes, Hepatic viruses A, B, C, D, E
58
What accounts for 30% of transplants in US?
Chronic hep C

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