Autism Flashcards
Autism is diagnosed between ages __-__ and has a prevalence of __%
2-5; 1%
____ (sex) with autism tend to be more impaired, but have a lower chance of autism overall
Females
What are the two reasons the prevalence of autism has gone up recently?
chagin in diagnostic criteria; better awareness
What were the two major issues with the DSM IV autism criteria?
No biological basis and not predicted by treatment response
What are the three major factors of an ASD?
Communication impairment, social impairment, and restricted interests
What two major DSM IV criteria got dropped?
Separate social and communication impairment and universal language delay
The ____ property of autism and its comorbidities make it impossible to categorize and treat the disorder broadly
heterogenous
25% of children with _____ syndrome have autism
fragile X
22q13 deletions involve what gene?
SHANK3
The sibling recurrence rate for autism is __; and for MZ twins its
20%; 70%
There are over 500 genetic risk variant for autism and many of these genes exhibit ____ effects- one gene affecting many
pleiotropic
Most environmental factors have a ____ effect
epigenetic
What are the three most common environmental factors?
Thalidomide, Valproic acid, Maternal rubella infection
Two ways which we can study autistic kids are
questionnaires and direct assessment
Impaired ___ ____, or reward from socializing, may lead to autistic kids not being able to communicate well later
social motivation
