Marijuana

Question 1

Other than THC, two other important components are

Answer 1

CBD and THCV

Question 2

THC acts on __ receptors

Answer 2

GCPRs

Question 3

CB1 receptors are found where

Answer 3

CNS, adipocytes, liver, muscle

Question 4

CB2 receptors are found exclusively on ___ nerves on ___ cells

Answer 4

peripheral; immune

Question 5

Endocannabinoids promote (4) things

Answer 5

appetite, sleep, lower intraocular pressure, apoptosis

Question 6

____ released from the postsynaptic neuron binds to ___ on the presynaptic neuron to inhibit ___ release

Answer 6

2-AG; CB1; GABA

Question 7

Which receptor is responsible for psychoactivity?

Answer 7

CB1

Question 8

What is the role of CBD?

Answer 8

anandamide degradation

Question 9

__ is a CB1 antagonist

Answer 9

CBV

Question 10

Edibles are subject to the ___ __ effect

Answer 10

first pass

Question 11

The peak level of cannabis in plasma is 100mg- the psychotropic effects ___ the plasma level after inhalation

Answer 11

lag

Question 12

Marijuana is metabolized in the __

Answer 12

liver

Question 13

A single joint can cause positive testing for up to

Answer 13

8-96 hours

Question 14

Urine drug screens only test positive ___ use

Answer 14

after

Question 15

_____ and ___ are FDA approved medical cannabinoids-

Answer 15

Dronabinol (nausea, wasting) and Nabilone (pain)

Question 16

Chronic mary J users who are more prone to ____ have earlier onset of it

Answer 16

schizophrenia

Question 17

There is a risk of ____ and dependence with marijuana

Answer 17

apathy

Question 18

Marijuana may cause ____ syndrome

Answer 18

metabolic

Question 19

Dependence, tolerance, and withdrawal are not associated with marijuana (T/F)

Answer 19

False, they are

Question 20

Naloxone mimics ____ in and blocks ___ in healthy rats

Answer 20

opiate withdrawal; weed induced analgesia