Principles of Psychopharm

Question 1

What are the most commonly prescribed drugs?

Answer 1

Psychiatric Agents

Question 2

Serotonin originates where?

Answer 2

Raphe Nuclei

Question 3

Norepi originates where?

Answer 3

Locus Ceruleus

Question 4

Where does dopamine originate?

Answer 4

VTA and Substantia nigra

Question 5

Phencyclidine can be used to block ___ and mimic which disease?

Answer 5

NMDA receptors; schizophrenia

Question 6

GABA agents merely treat _____ not the ____ ____

Answer 6

symptoms; underlying condition

Question 7

Fear of ___ can be treated completely with GABA agents

Answer 7

flying

Question 8

Antipsychotics target the ___ receptor for dopamine and ___ the amount of dopamine

Answer 8

D2; decrease

Question 9

Negative symptoms like poor hygiene and social isolation are modulated by

Answer 9

mesocortical pathway

Question 10

Positive symptoms like delusions and perceptual disturbances are modulated by

Answer 10

mesolimbic pathway

Question 11

Side effects of dopamine agents in the _____ include movement disorders

Answer 11

nigrostriatal area

Question 12

Side effects of the tuberoinfundibular pathway include

Answer 12

prolactin effects

Question 13

First generation antipsychotics are known as ___ and are divided into ___ and __ potency groups

Answer 13

typicals; high; low

Question 14

Low potency antipsychotics have ___ side effects

Answer 14

more

Question 15

Antihistamine effects are (2)

Answer 15

weight gain, sedation

Question 16

Anticholinergic effects include these two major ones

Answer 16

dry mouth, constipation

Question 17

Antiadrenergic effects include (2)

Answer 17

arrhythmias, orthostasis

Question 18

Second generation antipsychotics are _____ because they not only block D2 receptors but also ____

Answer 18

atypicals; 5HT (serotonin)

Question 19

Second generation antipsychotics are not more ____ but they are better _____

Answer 19

effective; tolerated

Question 20

A unique side effect of Second generation antipsychotics is

Answer 20

metabolic syndrome

Question 21

The drug with the strongest association with metabolic syndrome is

Answer 21

olanzapine

Question 22

Clozapine may cause

Answer 22

agranulocytosis

Question 23

All antidepressants increase the level of _____

Answer 23

monoamines

Question 24

Patients on MAOIs should avoid _____ found in aged, cured, and fermented foods

Answer 24

tyramine

Question 25

TCAs are ____ with overdose

Answer 25

fatal

Question 26

SNRI also help with

Answer 26

pain

Question 27

____ and ____ are shown to reduce the risk of suicide

Answer 27

Lithium, clozapine

Question 28

These three benzos are liver sparing

Answer 28

lorazepam, oxazepam, temazepam

Question 29

Alprazolam has a __ onset and a __ duration

Answer 29

quick; short

Question 30

___ are the safest and best tolerated anti-depressants

Answer 30

SSRIs