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DRUGS > Drug Reactions > Flashcards

Drug Reactions Flashcards

1
Q

(cardiovascular) Coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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2
Q

(cardiovascular) Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, Ca2+ channel blockers; Mnemonic: “VANC”

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3
Q

(cardiovascular) Dilated cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

(cardiovascular) Torsades de pointes

A

Class III (e.g., sotalol) and class IA (e.g., quinidine) antiarrhythmics, macrolide antibiotics, antipsychotics, TCAs

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5
Q

(endocrine/reproductive) Adrenocortical insufficiency

A

HPA suppression 2¡ to glucocorticoid withdrawal

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6
Q

(endocrine/reproductive) Hot flashes

A

Tamoxifen, clomiphene

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7
Q

(endocrine/reproductive) Hyperglycemia

A

Tacrolimus, Protease inhibitors, Niacin, HCTZ, beta-blockers, Corticosteroids; Mnemonic: “Taking Pills Necessitates Having Blood Checked”

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8
Q

(endocrine/reproductive) Hypothyroidism

A

Lithium, amiodarone, sulfonamides

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9
Q

(GI) Acute cholestatic hepatitis, jaundice

A

Erythromycin

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10
Q

(GI) Diarrhea

A

Metformin, Erythromycin, Colchicine, Orlistat, Acarbose; Mnemonic: “Might Excite Colon On Accident”

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11
Q

(GI) Focal to massive hepatic necrosis

A

Halothane, Amanita phalloides (death cap mushroom), Valproic acid, Acetaminophen; Mnemonic: Liver “HAVAc”

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12
Q

(GI) Hepatitis

A

INH

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13
Q

(GI) Pancreatitis

A

Didanosine, Corticosteroids, Alcohol, Valproic acid, Azathioprine, Diuretics (furosemide, HCTZ); Mnemonic: “Drugs Causing A Violent Abdominal Distress”

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14
Q

(GI) Pseudomembranous colitis

A

Clindamycin, ampicillin, cephalosporins ; Mnemonic: Antibiotics predispose to superinfection by resistant C. difficile

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15
Q

(Hematologic) Agranulocytosis

A

Dapsone, Clozapine, Carbamazepine, Colchicine, Methimazole, Propylthiouracil; Mnemonic: Drugs CCCrush Myeloblasts and Promyelocytes

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16
Q

(Hematologic) Aplastic anemia

A

Carbamazepine, Methimazole, NSAIDs, Benzene, Chloramphenicol, Propylthiouracil; Mnemonic: Can’t Make New Blood Cells Properly

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17
Q

(Hematologic) Direct Coombs- positive hemolytic anemia

A

Methyldopa, penicillin

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18
Q

(Hematologic) Gray baby syndrome

A

Chloramphenicol

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19
Q

(Hematologic) Hemolysis in G6PD deficiency

A

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin; Mnemonic: Hemolysis IS D PAIN

20
Q

(Hematologic) Megalo”blast”ic anemia

A

Phenytoin, Methotrexate, Sulfa drugs; Mnemonic: Having a blast with PMS

21
Q

(Hematologic) Thrombocytopenia

A

Heparin, cimetidine

22
Q

(Hematologic) Thrombotic complications

A

OCPs (e.g., estrogens)

23
Q

(Musculoskeletal/skin/connective tissue) Fat redistribution

A

Protease inhibitors, Glucocorticoids; Mnemonic: Fat PiG

24
Q

(Musculoskeletal/skin/connective tissue) Gingival hyperplasia

A

Phenytoin, verapamil, cyclosporine, nifedipin

25
Q

(Musculoskeletal/skin/connective tissue) Hyperuricemia (gout)

A

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine; Mnemonic: Painful Tophi and Feet Need Care

26
Q

(Musculoskeletal/skin/connective tissue) Myopathy

A

Fibrates, niacin, colchicine, hydroxychloroquine, interferon-, penicillamine, statins, glucocorticoids

27
Q

(Musculoskeletal/skin/connective tissue) Osteoporosis

A

Corticosteroids, heparin

28
Q

(Musculoskeletal/skin/connective tissue) Photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines, 5-FU; Mnemonic: “SAT For Photo”

29
Q

(Musculoskeletal/skin/connective tissue) Rash (Stevens- Johnson syndrome)

A

Antiepileptic drugs (ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital), Allopurinol, Sulfa drugs, Penicillin; Mnemonic: “Steven Johnson has epileptic Allergy to Sulfa drugs and Penicillin”

30
Q

(Musculoskeletal/skin/connective tissue) SLE-like syndrome

A

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept; Mnemonic: Having lupus is “SHIPP-E”

31
Q

(Musculoskeletal/skin/connective tissue) Teeth discoloration

A

Tetracyclines

32
Q

(Musculoskeletal/skin/connective tissue) Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

33
Q

(Neurologic) Cinchonism

A

Quinidine, quinine

34
Q

(Neurologic) Parkinson-like syndrome

A

Antipsychotics, Reserpine, Metoclopramide ; Mnemonic: Cogwheel rigidity of ARM

35
Q

(Neurologic) Seizures

A

INH (vitamin B6 deficiency), Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclopramide; Mnemonic: With seizures, I BITE My tongue

36
Q

(Neurologic) Tardive dyskinesia

A

Antipsychotics, metoclopramide

37
Q

(Renal/genitourinary) Diabetes insipidus

A

Lithium, demeclocycline

38
Q

(Renal/genitourinary) Fanconi syndrome

A

Expired tetracycline

39
Q

(Renal/genitourinary) Hemorrhagic cystitis

A

Cyclophosphamide, ifosfamide ; Rx:Prevent by co-administering with mesna

40
Q

(Renal/genitourinary) Interstitial nephritis

A

Methicillin, NSAIDs, furosemide

41
Q

(Renal/genitourinary) SIADH

A

Carbamazepine, Cyclophosphamide, SSRIs ; Mnemonic: Can’t Concentrate Serum Sodium

42
Q

(Respiratory) Dry cough

A

ACE inhibitors

43
Q

(Respiratory) Pulmonary fibrosis

A

Bleomycin, Amiodarone, Busulfan, Methotrexate; Mnemonic: Breathing Air Badly from Medications

44
Q

Antimuscarinic

A

Atropine, TCAs, H1-blockers, antipsychotics

45
Q

Disulfiram-like reaction

A

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st-generation sulfonylureas

46
Q

Nephrotoxicity/ ototoxicity

A

Aminoglycosides, vancomycin, loop diuretics, cisplatin

DRUGS (41 decks)

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