3rd defense: acquired immunity Flashcards Preview

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Flashcards in 3rd defense: acquired immunity Deck (13):
1

basic characteristic of adaptive/acquired immunity

recognition of self
specificity
diversity
memory
can be acquired actively or passively

2

define specificity

immunity to agent is specific to that agent only. immunity to one strain vs others

3

define diversity

potential to recognize and interact diff epitotes through antigen-binding sites on Ab and T cell receptors

4

define memory

retains memory against specific immunogens through memory T and B cells

5

define active immunity

generates own protective immune products (Ab/ Tcells) under natural or artificial conditions

6

define passive immunity

receives protective immune products from donor source. natural or artificial

7

eg of naturally acquired passive immunity

transfer of aB from mother to fetus

8

eg of artificial acquired passive immunity

injection of immune globulins IG or immune serum containing pre formed Ab from donor

9

define immunoprophylaxis

use of vaccines and immune globulins in prevention of diseases

10

ideal characteristics of effective vaccine (6)

-low level of adverse side effects
-protect against exposure to natural wild forms of pathogen
-stimulate antibody (b-cell) response and cell mediated (t cell) response
-not require numerous doses
-inexpensive, long shelf life, easy

11

define vaccines

agents used to induce active immunity

12

define immune globins or antisera

contain pre formed antibodies from donor source against infectious agents

13

when to use immune globins

when live vaccines not recommended for pregnant or immunocompromised. vaccine not available (eg botulism). immediate protection eg tetanus-IG shot. inconjunction w/ vaccines post exposure prophylaxis eg rabies