Osteoporosis Flashcards
1
Q
What is the core therapy for osteoporosis?
A
Bisphosphonates
2
Q
What are some examples of bisphosphonates?
A
Alendronate
Risendronate
Zolendronate- IV
Ibandronate- IV
3
Q
What are the indications for bisphosphonate use?
A
Primary prevention of osteoporosis in post menopausal women and steroid therapy
4
Q
In which patient group do bisphosphonates have a weaker evidence base?
A
> 80 yo- may require just vitamin D or calcium instead, or longer acting bisphosphonates
5
Q
What may be prescribed with bisphosphonates?
A
Vitamin D and calcium
6
Q
What are the side effects of bisphosphonates?
A
Mild GI sx Oesophageal ulceration/erosion Diffuse musculoskeletal pain Osteonecrosis of the maxilla (rare) Hypercalcaemia
7
Q
What other medications are used to treat osteoporosis other than bisphosphonates?
A
HRT/raloxifene- CV risk, malignancy
Teriparatide
Denosumab- severe hypcalcaemia
