Migraine Flashcards

1
Q

Mx acute episodes of migraine?

A

Paracetamol/aspirin + metoclopramide/domperidone (latter used less due to arrhythmia concerns)

NSAID + metoclopramide/domperidone

Triptans- give PO, IM, SL. Avoid in CHD, uncontrolled HTN

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2
Q

Prevention of migraines?

A

Avoid triggers

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3
Q

What medications have the best evidence for migraine prevention?

A
Propanolol
Amitriptyline
Metoprolol
Topiramate
Gabapentin
Botox
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4
Q

What is an example of an antimuscarinic anti-emetic?

A

Hyoscine

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5
Q

What is hyoscine used for?

A

Motion sickness

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6
Q

What is an example of an antihistamine anti-emetic?

A

Cinnarizine, cyclizine

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7
Q

What is cyclizine used for?

A

Motion sickness

Vestibular disorders

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8
Q

What is an example of an DA agonist anti-emetic?

A

Metoclopramide

Domperidone

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9
Q

What are DA agonist anti-emetics used for?

A

Post-op nausea

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10
Q

What is an example of an 5-HT3 antagonist anti-emetics?

A

Ondansetron

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11
Q

What is ondansetron used for

A

Chemical induced nausea e.g. post chemo, postop

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12
Q

What is an example of a steroid anti-emetic?

A

Dexamethasone

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13
Q

When is dexamethasone used as an anti-emetic?

A

Chemotherapy

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14
Q

What is an example of a cannabinoid anti-emetic?

A

Nabilone

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15
Q

What is the anti-emetic combination used in chemotherapy?

A

Neurokinin antagonists + 5-HT3 antagonists + dexamethasone

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16
Q

What is an example of a neurokinin antagonist anti-emetic?

A

Aprepitant