2/7/13 b

Question 1

What is the difference in pulmonary capillary wedge pressure (PCWP) between ARDS and CHF?

Answer 1

<18 in ARDS

Question 2

What is Conn’s syndrome?

Answer 2

primary hyperaldosteronism

Question 3

What is the bicarb level in Conn’s syndrome? Why?

Answer 3

high; H+ excreted in exchange for Na+

Question 4

Which type of WBCs will glucocorticoids be most likely to increase?

Answer 4

PMNs

Question 5

How do glucocorticoids increase serum neutrophil count?

Answer 5

mobilizing the marginated neutrophil pool

Question 6

How do you define diabetic nephropathy?

Answer 6

albumin:creatinine >30mg/g

Question 7

What are ythe most common side fx of digoxin toxicity?

Answer 7

GI: anorexia, nausea, vomiting

Question 8

What is the cause of hypertension in hyperthyroidism?

Answer 8

“hyperdynamic circulation”

Question 9

Febrile reaction, a common transfusion reaction that is usu. relieved w/ acetaminophen or NSAIDs, is a result of the pt’s plasma reacting with the donor’s _______.

Answer 9

leukocytes

Question 10

What is the most common type of nephrotic syndrome in adults?

Answer 10

focal segmental glomerulosclerosis

Question 11

In membranous nephropathy caused by HBV, what deposits in the glomeruli?

Answer 11

HBeAg or the corresponding Ab

Question 12

What is the classic CSF finding in Guillain-Barre syndrome?

Answer 12

albumino-cytologic dissociation

Question 13

What is the only medication for ALS?

Answer 13

riluzole

Question 14

What is the Tx for inflammatory myopathies such as polymyositis and dermatomyositis?

Answer 14

hi-dose corticosteroids

Question 15

Positive nitrites in a urine dipstick in a pt w/ UTI specifically indicate the presence of _______.

Answer 15

Enterobacteriaciae (e.g. E. coli)

Question 16

How would you characterize the cervical lymphadenopathy of cancer?

Answer 16

hard and immobile

Question 17

What are the additional risk factors for focal segmental glomerulosclerosis?

Answer 17

African American, HIV, obesity, and heroin use

Question 18

What diseases would predispose to amyloidosis?

Answer 18

multiple myeloma and chronic inflammatory disease (e.g. RA)

Question 19

Tinnitus, fever, tachypnea, nausea, and vomiting are highly suggestive of toxicity with _______.

Answer 19

aspirin (salicylates)

Question 20

How does aspirin toxicity cause alkalosis?

Answer 20

stimulates respiratory centers

Question 21

What 2 acid-base abnormalities does salicylate poisoning cause concurrently?

Answer 21

respi alk and meta acid (anion gap)

Question 22

Fever, tinnitus, and tachypnea should make you suspect what toxicity?

Answer 22

aspirin

Question 23

What is the most common genetic hypercoagulability disorder?

Answer 23

Factor V Leiden

Question 24

What is unusual about Factor V in Factor V Leiden?

Answer 24

resistant to inactivation by protein C

Question 25

Which type of inflammatory arthritis causes dactyltis (“sausage fingers”)?

Answer 25

psoriatic arthritis

Question 26

What is the most common cutaneous manifestation of sarcoidosis?

Answer 26

erythema nodosum

Question 27

What is erythema nodosum?

Answer 27

inflammation of the fat cells underneath the skin of both shins

Question 28

What 3 kinds of meds are used to Tx psoriatic arthritis?

Answer 28

NSAIDs, anti-TNF, and MTX

Question 29

What kind of drug, used to treat other inflammatory conditions is relatively contraindicated in psoriatic arthritis?

Answer 29

corticosteroids

Question 30

What is thought to be the pathogenesis of neuropathic arthropathy?

Answer 30

lack of proprioception –> repeated trauma –> destruction of joint

Question 31

Which group of ppl is neuropathic arthritis seen most commonly in?

Answer 31

diabetics