2/13/13

Question 1

What is the Tx for granulomatosis w/ polyangiitis?

Answer 1

cyclophosphamide and steroids

Question 2

What is the Tx for Goodpasture’s syndrome?

Answer 2

emergency plasmapheresis

Question 3

What should be given concurrently with TMP-SMX to pts w/ pneumocystic pneumonia and a PaO2 <70mmHg?

Answer 3

prednisolone

Question 4

What are the 2 causes of renal dysfunction in pts w/ multiple myeloma?

Answer 4

hypercalcemia and light chain (Bence-Jones protein) deposition

Question 5

How would a Swan-Ganz catheter measurement differentiate ARDS from CHF induced pulmonary edema? (Give the number.)

Answer 5

ARDS has PCWP <18 mmHg

Question 6

What causes a distolic decrescendo murmur in the left 3rd intercostal space that increases w/ handgrip?

Answer 6

aortic regurgitation

Question 7

What is primary medical therapy for aortic regurgitation?

Answer 7

afterload reduction as w/ nifedipine or ACE-I’s

Question 8

Which CHF medications are contraindicated in aortic regurgitation? Why?

Answer 8

β-blockers; lengthen diastole and time for regurgitation

Question 9

What is the most common renal pathology seen in analgesic nephropathy aside from papillary necrosis?

Answer 9

tubulointerstitial nephritis

Question 10

What kind of acute renal failure is caused most commonly by toxins or ischemia and demonstrates muddy brown granular casts on urinalysis?

Answer 10

Acute tubular necrosis

Question 11

_______ is characterized by sudden, painless loss of vision in one eye, and the fundoscopic examination reveals pallor of the optic disk, a cherry red fovea, and “boxcar segmentation” of blood in the retinal veins.

Answer 11

Central retinal artery occlusion (CRAO)

Question 12

How do you usually treat dissection of the descending aorta (Stanford type B aortic dissection)?

Answer 12

IV labetalol

Question 13

Dx this: pruritic, elevated, serpiginous lesions on the skin after contact w/ sand or soil in a tropical/subtropical region.

Answer 13

cutaneous larva migrans

Question 14

What two classes of Abx may be used to treat Legionairre’s disease?

Answer 14

macrolides or fluoroquinolones

Question 15

What is the antibiotic of choice in aspiration pneumonia?

Answer 15

clindamycin

Question 16

One of which 2 procedures should be used to confirm the Dx of Legionairre’s disease?

Answer 16

urine Ag or culture

Question 17

What medium do you culture Legionella on?

Answer 17

chocolate agar

Question 18

What is the single most common cause of asymptomatic, isolated elevation of alk phos in an elderly pt?

Answer 18

Paget’s disease of bone

Question 19

What valvulopathy causes a bounding or “water hammer” pulse?

Answer 19

AR

Question 20

What is the most typical site of bleeding in hemophiliacs?

Answer 20

joints (hemarthroses)

Question 21

What statistical method should be used to compare the means of 2 sample groups?

Answer 21

Two-sample T test

Question 22

What statistical method is used to compare 3 or more means?

Answer 22

ANOVA

Question 23

What kind of drug is the drug of choice for mild to moderate hypercalcemia d/t malignancy?

Answer 23

bisphosphonates (e.g. Zoledronic acid)