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SP2017 Micro Exam#2 > antibacterial immunity > Flashcards

antibacterial immunity Flashcards

1
Q

both … and… are critical for extracellular bacteria (e. coli, staph, strep, pseudo)

A

innate and adaptive

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2
Q

… attacks invaders outside the cell

A

B

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3
Q

… attacks invaders inside cell

A

T

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4
Q

phagocytosis of extracellular bacteria, .. and… will do this

A

neutrophils and macrophages

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5
Q

High affinity receptors in recognition of microbe by phagocyte

A

mannose receptor
mac-1 integrin
scavenger recep.

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6
Q

scavenger receptor binds microbe directly like mannose but does not bind to

A

mannose

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7
Q

mannose attaches

A

directly

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8
Q

mac-1 integrin binds microbes…. with complement proteins

A

opsonized

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9
Q

… is derived from greek word meaning “to prepare for eating”

A

opsonin

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10
Q

opsonin’s can be…

A

antibodies
complement proteins
lectin

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11
Q

After engulfment and formation of phagosome there is fusion with … and…

A

lysosome and phagosome

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12
Q

respiratory burst is when

A

activated macrophages and neutrophils will convert molecular oxygen into ROS

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13
Q

Th1 make

A

inflammatory cytokines

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14
Q

Th2 make

A

B cell promoting cytokines

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15
Q

CD4+ T cells make inflammatory cytokines.. and… which promote

A

IFN y

TNF alpha

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16
Q

CD4+ produce cytokines … …. and ..

A

IL 4
IL5
IL10

17
Q

th2 is important for…

A

extracellular defense

18
Q

… immune response is dominant rather than antibody response

A

cell mediated

19
Q

both… are involved in intracellular pathogens

A

innate and adpative

20
Q

adaptive for intracellular

A

CD4

CD8

21
Q

innate for intracellular

A

dendritic
NK
macrophage/neutrophils

22
Q

adaptive for extracellular

A 
B cells and antibody IgG
T cells (indirect by CD4)
23
Q

innate for extracellular

A

macrophages
neutrophils
complement

24
Q

dendritic are..

A

professional APCs that present antigen to T cells.

to LN

25
Q

th1 is important for

A

intracellular

26
Q

NK secrete

A

INF y

27
Q

CD4+ T helper recognize

A

MHCII

28
Q

th1 cd4 t cells produce… and.. and promote….

*Provide help to CD8+ t cells and macrophages

A

IFN y and TNF alpha

cell mediated immunity

29
Q

th2 cd4 t cells produce .. and promote…

*provide help to B cells

A

IL-4

antibody mediated immunity

30
Q

CD8 are called… as they secrete … and… whic can directly lyse and kill infected cells

A

cytotoxic T cells
perforin
granzymes

31
Q

CD8 great for.. immunity

A

antiviral

32
Q

CD8 also secrete

A

INF y and TNF alpha

33
Q

CD8 recognize antigen in

A

MHCI

SP2017 Micro Exam#2 (12 decks)

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