Abdominal aortic aneurysm (AAA) Flashcards

1
Q

What is the definition of a AAA?

A

Permanent localised dilatation of the aorta

Vessel diameter >3 cm

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2
Q

How common is a AAA?

A

Prevalence in the UK of 1.3-12.7% in the UK

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3
Q

What is the pathology of an AAA?

A
  • Most arise from below the level of the renal arteries
  • Mostly caused by a degenerative process
  • Degradation of the elastic lamellae
  • Enhanced proteolysis
  • Smooth muscle cell loss
  • Affects all 3 layers of the arterial wall
  • Symptoms caused by pressure/rupture
  • RUPTURE IS A MEDICAL EMERGANCY
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4
Q

What are the risk factors/aetiology of AAA’s?

A
  • Elderly
  • Men – though the risk of rupture is greater in woman
  • Atherosclerotic damage
  • Family history
  • Smoking
  • Hypertension
  • COPD
  • Hyperlipidaemia
  • Trauma
  • Infection e.g. HIV, TB
  • Inflammatory diseases
  • Connective tissue disease
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5
Q

What are the signs/symptoms of an AAA?

A
  • Can be asymptomatic
  • Epigastric/back/loin/groin pain
  • Pulsating mass on abdominal examination
  • Features of limb ischemia
  • Abdominal bruit
  • Grey Turner’s sign – retroperitoneal haemorrhage
  • Rupture:
  • Hypotension
  • Abdominal symptoms
  • Acute severe lumbar/abdomen/loin pain
  • Syncope
  • Shock
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6
Q

What investigations are carried out for a suspected AAA?

A
  • FBC, clotting screen, U&E’s, LFT
  • Cross match
  • ECG
  • X ray
  • Shows calcification
  • US
  • CT
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7
Q

How does having an AAA affect a patients ability to drive?

A

May not drive if aneurysm is >6.5cm – may be relicensed after surgery

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8
Q

What are the surgical treatments for an AAA?

A
  • Surgical replacement with prosthetic graft – symptomatic aneurysms/large asymptomatic aneurysms
  • Open repair
  • Endovascular repair with insertion of aortic stent – for those that are poor surgical risk
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9
Q

What are the pharmacological treatments for an AAA?

A
  • Antihypertensives

* Statins

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10
Q

What are the non pharmacological treatments for an AAA?

A
  • Regular US monitoring
  • Smoking cessation
  • AAA screening above the age of 65
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