Physiology: pain Flashcards
1
Q
Physiology: pain
pain resulting from a stimulus that usually does not provoke pain
A
allodynia
2
Q
Physiology: pain
Following joint or muscle inflammation __________ of primary afferent fibers occurs
A
sensitization
increase in spontaneous activity → increase response to the same noxious stimulus
3
Q
Physiology: pain
substances are released from inflammatory cells that can activate or sensitize primary afferent fibers
A
- Serotonin: causes pain in humans, released from platelets.
- Bradykinin: released from plasma after tissue damage.
- Prostaglandins
- Cytokines
4
Q
Physiology: pain
gate control theory
A
Activation of large diameter afferent fibers by pressure, proprioception, touch or vibration inhibits transmission of pain by small afferent fibers
5
Q
Physiology: pain
types of pain
A
mechanical, chemical (inflammatory), neurogenic/psychological (chronic low back pain)
