Pain

Question 1

3 pain pathways

Answer 1

1. spinotectal
2. spinoreticular
3. spino-thalamic

Question 2

spinotectal pathway projections

Answer 2

descending feedback

goes to raphe nucleus which goes back to the ipsilateral dorsal horn

Question 3

opioids inhibit what?

Answer 3

the pathway from the raphe nucleus back to ipsilateral dorsal horn in the spinotectal pathway

Question 4

spinoreticular pathway projections

Answer 4

goes to reticular formation which projects to the cerebral cortex and is widespread

Question 5

what kind of pain is the spinoreticular pathway responsible for?

Answer 5

motivational-affective pain

Question 6

spinothalamic pathway projections

Answer 6

to either the lateral thalamus and then the primary somatosensory cortex
or to the medial thalamus and then to the cerebral cortex

Question 7

what kind of pain is the spinothalamic pathway responsible for?

Answer 7

well actually two kinds:
if it goes to the lateral thalamus then it will cause sensory-discriminative pain
but if it goes to the medial thalamus it will cause motivational-affective pain

Question 8

Brown-Sequard Syndrome

Answer 8

sectioning 1/2 of the spinal cord will block central transmission of dorsal column inputs from ipsilateral receptors and of anterolateral column inputs from contralateral receptors

Question 9

what is the result in brown-sequard syndrome?

Answer 9

• ipsilateral loss of discriminative tactile and proprioceptive sensations
• contralateral loss of thermal and nociceptive sensations
• ipsilateral paralysis