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Physio I > PTH/Vit. D > Flashcards

PTH/Vit. D Flashcards

1
Q

intracellular Calcium is generally low or high?

A

low intracellular, high extracellulary

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2
Q

where is most calcium located?

A

in the bone

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3
Q

what is vitamin d’s main purpose?

A

to increase calcium reabsorption

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4
Q

where is vitamin d’s primary target?

A

the gut

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5
Q

what is the regulation of calcium linked with?

A

phosphate levels

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6
Q

calcium and phosphate are both required for

A

bone mineralization

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7
Q

osteoblasts do what?

A

bone formation

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8
Q

osteoclasts do what?

A

bone breakdown

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9
Q

estrogen promotes

A

osteoblasts

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10
Q

vitamine D and PTH both primarily act on

A

osteoblasts

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11
Q

high level of cortisol stimulate

A

osteoclasts

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12
Q

parathyroid hormonen is produced in

A

the parathyroid gland by chief cells

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13
Q

PTH stimulates calcium

A

reabsorption in the kidney

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14
Q

PTH promoters the conversion of

A

vitamin D to active form

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15
Q

calcitonin reduces

A

osteoclast activity

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16
Q

vitamin D regulates

A

calcium levels in the obdy

17
Q

vitamin D stimulates calcium absorption form

A

the gut

18
Q

direct action of PTH at the - kidneys

A

decreases excretion of calcium
increases excretion of phosphate
stimulates active form of vip D

19
Q

direct action of PTH at the - bone

A

increases the number + activity of osteoclasts

20
Q

indirect action of PTH at the - kidneys

A

increased calcium reabsorption in tubules

21
Q

indirect action of PTH at the - bone

A

increase calcium reabsorption

22
Q

where does Vit D primarily have it’s effect?

A

on the GI tract

23
Q

vit D action at the bone is to promote

A

bone mineralization

24
Q

vit d affects at the kidney is to act synergistically with PTH to promote

A

calcium reabsorption

25
Q

rickets

A

deficiency of vitamin D in children

26
Q

osteomalacia

A

deficiency of vitamin D in adults

27
Q

osteoporosis major risk factor is

A

decline in estrogen levels in aging women

28
Q

cushing’s disease can cause

A

osteoporosis

29
Q

what can help osteoporosis?

A

weight baring activities

Physio I (26 decks)

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