SG Sodium Handling Flashcards
What is the volume of the intracellular compartment?
28L
What is the volume of the interstitial space?
10.5L
What is the volume of the intravascular space?
3.5L
What can flow passively btw the intracellular space and the interstitium?
water
What can flow passively btw the interstitium and the intravascular space?
Na, Cl, water
What is found in the plasma?
proteins, esp albumin and IVIGs
If albumin is given to the patient, in which spaces will the albumin be found?
only w/i the intravascular space
If salt is given to the patient, in which spaces will the salt be found?
in the interstitium and the intravascular spaces
Which diuretic works upon the proximal convoluted tubule?
acetazolamide
Which diuretic works upon the thich ascending Loop of Henle?
furosemide
Which diuretic works upon the distal convoluted tubule?
thiazide, amiloride
Which diuretic works upon the collecting duct?
spironolactone, triampterone
How does acetazolamide work?
it inhibits carbonic anhydrase
How does furosemide work?
it inhibits the Na/K/Cl cotransporter
How do thiazide diuretics work?
they inhibit the Na/Cl transporter
