Medical consequences of alcohol excess - Week 6 Flashcards

1
Q

How many ml of alcohol equates to 1 unit of alcohol?

A

10ml

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2
Q

How many units does a standard bottle of beer equate to?

A

1.6 units

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3
Q

How many units does a medium glass of wine equate to?

A

2.3 units

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4
Q

How many ml of spirits is 1 unit of alcohol?

A

25ml

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5
Q

Give some acute GI issues that can be caused by excess alcohol consumption.

A

Oesophagitis, Gastritis/ulceration

Acute Pancreatitis

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6
Q

Chronic excess alcohol consumption can cause issues with which GI organs?

A

Stomach, pancreas, liver

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7
Q

Give 4 cardiovascular effects of chronic excess alcohol consumption.

A

Hypertension
Cardiomyopathy
Myocardial infarction
Stroke

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8
Q

Give 4 CNS effects of chronic excess alcohol consumption.

A

Neuropathies
Cerebellar degeneration
Dementia
Wernicke-Korsakoff’s syndrome

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9
Q

Exposure of children to alcohol in utero may cause…

A

Foetal Alcohol Syndrome

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10
Q

Foetal Alcohol Syndrome results in…

A

growth deficiency, mental retardation/intellectual impairment, attentional learning disabilities & behavioural problems

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11
Q

How is alcohol metabolised?

A

Alcohol Dehydrogenase converts Ethanol to Acetaldehyde which is then converted to acetate by Aldehyde Dehydrogenase.

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12
Q

What is meant by Steatosis?

A

Fatty liver disease

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13
Q

What is meant by steatohepatitis?

A

Alcoholic Hepatitis

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14
Q

Is Cirrhosis reversible?

A

No

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15
Q

The majority of heavy alcohol abusers will develop…

A

Steatosis

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16
Q

Give clinical signs of chronic liver disease.

A

spiders, fetor, encephalopathy, prolonged prothrombin time, hypoalbulinaemia

17
Q

Give clinical signs of portal hypertension.

A

caput medusa
hypersplenism
Thrombocytopenia

18
Q

How is Cirrhosis graded?

A

Childs-Turcotte-Pugh score

19
Q

Give some clinical features of alcoholic hepatitis.

A

hepatomegaly, fever, leucocytosis, hepatic bruit

20
Q

Which score is used to estimate survival in alcoholic hepatitis?

A

Glasgow Alcoholic Hepatitis Score (GAHS)

21
Q

What is short-term treatment for alcoholic hepatitis?

A

Prednisolone