Flashcards in 7. Pain Deck (45)
What is the name given to pain receptors?
What kind of stimuli do nociceptors react to?
What sources do chemical stimuli come from?
What chemicals are released from damaged cells?
What chemical is released from platelets?
What chemicals are released from immune cells?
Which receptors detect cold?
What receptor detects heat?
What receptor detects protons?
What receptor detects bradykinin?
Which receptors detects mechanical stimuli?
What kind of fibres are type 1 pain fibres?
Small, myelinated, fast conduction
What sort of pain is transmitted through A-delta fibres?
Sharp, localised and immediate
Where does information from A-delta fibres go?
Thalamus and cortex
What NT is used in A-delta fibres?
What kind of fibres are type 2 pain fibres?
Small, unmyelinated, slow conduction
What sort of pain is transmitted through C fibres?
Dull, aching pain
Where does information from C fibres go?
What NT is used in C fibres?
Which sensory pathway does pain travel in?
What tract in the spinal cord do A-delta and C fibres ascend in?
Tract of Lissauer
Where do A-delta fibres synapse in the dorsal horn?
Layers I and V
Where do C fibres synapse in the dorsal horn?
Layer II (Substantia gelatinosa)
When do the pain fibres decussate?
Immediately after synapsing with the second order neuron
Which receptors does glutamate act on?
Which receptor does Substance P act on?
What are endogenous opioids?
Chemicals released to help modulate pain
What are the 3 types of opioid receptors?
What endogenous opioids are released in response to heat?