8 Flashcards
what is the mechanism of action of rivastigmine ?
a. cholinesterase inhibitor
b. alpha 1 receptor inhibitor
c. serotonin reuptake inhibitor
d. angiotensin converting enzyme inhibitor
a. cholinesterase inhibitor
page 1
which one of the following toxins can be used therapeutically?
a. aflatoxin
b. saxitoxin
c. alpha bungarotoxin
d. botulinum toxin
d. botulinum toxin
page 1
what is the recommended immunization schedule for tuberculosis ?
a. at birth
b. 6 weeks ,2 months , 6 months
c. 2,4, and 6 months
d. 6,12,and 18 months
a. at birth
page 1
what is the therapeutic effect of benzoyl peroxide in treatment of acne ?
a. keratolytic
b. antifungal
c. emollient
d. antiviral
a. keratolytic
page 2
what is the recommended immunzation schedule for measles , mumps and rubella vaccine?
a. birth
b. 6 weeks ,2 months , 6 months
c 2,4, and 6 months
d. 12 months an 4 years
d. 12 months an 4 years
page 2
a 27 year old man suffer form hepatitis c virus infection. His level of alanine aminotransferase and aspartate aminotransferase are high. In addition, liver biopsy showed mild fibrosis ( see lab results ).
test result normal values
alanine aminotrasnferase 75 5-40
aspartate aminotrnsferase 55 12-40 IU/L
which one of the followin drugs should be avoided in his case?
a. cephalexin
b. ampicillin
c. pregabalin
d. methotrexate
d. methotrexate
page 3
a diabetic patient has been diagnosed with hyperliidemia ( see lab results).
test result normal values
total cholesterol 6.5 <5.1 mmol/L
triglycerides 3.2<2.16 mmol/L
which one of the following drugs is the best option
a. ezetimibe
b. gemfibrozil
c. atorvastatin
d. cholestyramine
c. atorvastatin
page 4
which one of the following is a contra-indication of labetalol therapy?
a. anxiety
b. severe asthma
c. morning sickness
d. irritable bowel syndrome
b. severe asthma
page 4
what is the antidote for cholinesterase inhibitor mild toxicity?
a. atropine
b. carnitine
c. deferoxamine
d. sodium thiosulfate
a. atropine
page 5
a 49 year old man has high blood pressure despite following life style modification recommendations. HIs doctor is nor considering initiating treatment.
Which of the following drugs would be most appropriate?
a. doxazosin
b. lisinopril
c. propranolol
d. spironolactone
b. lisinopril
page 5
which of the following is a contraindication to the use of methotrexate?
a. pregnancy
b. tachycardia
c. pheochromocytoma
d. uncontrolled hypertension
a. pregnancy page 6
which of the folowing is a contraindication to isotretinoin therapy?
a. gallstones
b. essential hypertension
c. elevated blood lipid values
d. concomitant use with proton pump inhibitor
c. elevated blood lipid values
page 6
which of the following conditions is a serious adverse reaction of fluoroquinolone therapy?
a. eczema
b.. depression
c. nerve damage
d. abdominal pain
c. nerve damage
page 6
which of the following is a contraindication to isotretinoin therapy ?
a. gallstones
b. essential hypertension
c. elevated blood lipid values
d. concomitant use with proton pump inhibitors
c. elevated blood lipid values
page 7
which of the following conditions is a serious adverse reaction of fluoroquinolone therapy?
a. eczema
b. depression
c. nerve damage
d. abdominal pain
c. nerve damage
page 7
a 55 year old man presented to the hypertension clinic with uncontrolled blood pressure. He is currently using amlodipine 10mg per day. Ankle swellilng was observed during examination. A dipstick urine analysis revealed trace proteinuria.
blood pressure 160/100 mmHg
what will be the best drug to add in his prescription?
a.prazosin
b. enalapril
c. clonidine
d. metoprolol
b. enalapril
page 8
what is the validity of a registration certificate for pharmacy premises?
a. one year
b. three year
c. five years
d. ten year
c. five year
page 8
a 47 year old man was admitted to a psychiatric hospital in an acute psychotic state. her symptoms did not improve despite the use of adequate doses of two different anti-psychotic gents. the doctor is now cosidereing clozapine for her consition.
which of the following tests shoudl be carried out before initiation clozapine therapy?
a. presgnancy test
b. john cunningham virus DNA test
c. baseline absolute neutrophil count
d. magnetic resonance imaging of brain
c. baseline absolute neutrophil count
page 9
what is compassionate use of drug?
a. use of unapproved drug for seriously ill patient
b. use of approved drug in any patient
c. use of drug in wrong population
d. irrational drug use
a. use of unapproved drug for seriously ill patient
page 9
which of the following studies could establish the drug shelf life?
a. bioavailability
b. bioequivalennce
c. stability studies
d. pharmcodynamic
c. stability studies
pge 10
which one of the following is a seious adverse drug reaction?
a. urine discoloration caused by metronidazole
b. hospitalization due to bleeding caused by warfarin
c. tacycardia caused by salbutamol
d. throbbing headche caused by sildenafil
b. hospitalization due to bleeding caused by warfarin
page 10
which of the following can potential digoxin toxicity?
a. orlistat
b. migraine
c. amoxicillin
d. hypokalemia
d. hypokalemia
page 10
a 39 year old woman present to gastroentetology clinic with the chief complaint of bloody stool and weakness. Upon examination, no palpable mass was observed. Endoscopy reveal abnormal erythematous mucosa with ulceration. Her doctor told her that she has mild ulcerative colitis.
what would be the appropriate management?
a. bevacizumab
b. cyclosporine
c. sulfasalazine
d. pembrolizumab
c. sulfasalazine
page 11
which of the following is a contraindication to the use of lisinopril?
a. porphyria
b. addisons disease
c. history of angioedema
d. high grade aortic stenosis
c. history of angioedema
page 11
