Orion December Flashcards by Lovely jane Luchavez

38- What database do insurance companies use?

A- C.L.U.E.” database
Comprehensive Loss Underwriting Exchang

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39- Sources of data in insurance companies?
A- CLAIMS
b- Health data
C- Information collectio

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49- Which of the following error detection strategies result in limiting detection ?
A- bar-coding
B- trigger tools
C- voluntary reporting
D- mandatory reporting

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55- Mid goal to long term future goal?
A- Mission
B- Vision
C- Plan

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77- Preventive and curative institution is ?
A. primary
B. secondary
C. tertiary
D. specialty

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Preventive and curative institution is ?
A. primary
B. secondary
C. tertiary
D. specialty

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Mission and vision can be present in which strategy ?
A. Planning
B. Organization
C. Strategic

C. Strategic

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Long term plan use all aspects in organization
A- strategy
B- operation
C- organization

A- strategy

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pharmacist wrote email to another pharmacist to ask add medication to the
formulary in the hospital this is consider as ?
A. Inter institutional
B. Intra institutional
C. Written communication
D. Non Verbal communication

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-Head of pharmacy decide to make group to arrange formulary drugs in hospital?
A. organizing
B. planning
C. Leading

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who’s responsible for accreditation of health care system?
A- SFDA
B- WHO
C- MOH
D- CBAHI

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You received a prescription on a plain paper what to do ?
A. Tell the manager
B. Talk to the prescriber and don’t dispens

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pharmacist manager screemed on one of the pharmacist who dispensed wrong
medication in front of all the staff what is the good response ?
A. he should punish him in separate area
B. ask for a meeting with the staff
C. cut from his salary
D. try to find the cause of the error and set solution

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Which of the following is the function of the pharmacy and therapeutic committee in a
hospital?
A. Responsible for poison management
B. Monitor the adverse reaction reporting
C. Monitor the medication error reporting
D. Responsible for drug formulary managemen

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Which of the following distribution systems works better for medicine requiring a higher
level of control?
A. Bulk ward stock
B. Direct procurement
C. Automated dispensing
D. Individual medication order

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Which of the following committees is dedicated to developing and maintaining a list of
approved medicine for the hospital medicines for the hospital use ?
A. Medical records
B. Medication audit
C. Quality assurance
D. Pharmacy and therapeutics

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Which of the following is the definition of management?
A) The art of maximizing profitability
B) The art of maximizing productivity
C)The art of maximizing possibilities
D)The art of maximizing predictability

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A 65-year-old man presents to the pharmacy for a refill his medications. On review of his
refill history, the pharmacist noticed that he does not refill his medications regularly. Upon asking
him, the patient started that he has multiple medications that require complex administration.
Which of the following non adherence factors affecting above patient?
A. Patient related factors
B. Provider related factors
C. Health care system factors
D. Medication and condition factor

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which of the following need to be considered first by a pharmacist in order to rationalize drug
therapy decisions?
A. Care plan
B. Follow-up evaluations
C. Pharmacotherapy workup

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Most on prescription?
A- Patient name - mrn- date
B- Phystion name - numeber - signature
C- Pateint name - age - sex - daignosis
D- all above

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The hierarchy is showing Hospital X organizational chart. A pharmacist assigned as a clinical
pharmacist in neuroscience ward (see image)
Which of the following managerial position will the coworker re submitting a complaint?
A) Pharmacy Director
B) Medical affair Director
C) Neuroscience ward director
D) Clinical pharmacy department Head

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It is the broad range of health care services provided by in order to optimize therapeutic
outcomes for individual patients
Which of the following is the term used to describe the above- mentioned definition?
A. Pharmaceutical care
B. Medication counseling
C. Medication reconciliation
D. Medication therapy management

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which of the following anesthetics drug has a higher risk of causing hepatic toxicity?
A) propofol
B) ketamine
C) isoflurane
D) nitrous oxide

C) isoflurane

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Free medical sample drugs (formulary or non-formulary) are provided by pharmaceutical
sales representatives to physicians or members of the health care team.
Which of the following is the most appropriate recommended policy for dealing with sample
drugs?
A. Dispense them directly to the patient
B. Keep them with the rest of original items
C. Keep in outpatient clinics or nursing units
D. Exclude them from in-patient pharmacy, drug store or doctors’ offices

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which drug is used to treat an anaphylactic reaction? A. Atropine B. Adrenaline C. Isoprinosine D. Phentolamine

b. adrenaline

-which of the following medication has a side effect metalic taste ? A) cefuroxime B) azithromycin C) ciprofloxacin D) metronidazole

What is the type of anemia Lack of intrinsic factor? A- Megaloblastic anemia B- Pernicious anemia C- Hemolytic anemia D- Aplastic anemia

Which of the following is a consequence of stimulation of ꭤ1-Adrenoceptors? A. A flushing Adrenergic Receptors B. increased heart rate C. constricted bronchioles D. elevated blood pressure

D. elevated blood pressure

Which of the following is the mode of action of Phentolamine? A. beta-adrenergic blocker B. beta-adrenergic agonist C. alpha-adrenergic agonist D. alpha-adrenergic blocker (non selective alpha blocker)

D. alpha-adrenergic blocker (non selective alpha blocker)

Which of the following is the advantage of using intravenous anesthetic drug? A. Produce fast onset of anesthesia B. Helps in maintaining anesthesia C. Increases the minimum alveolar concentration (MAC) of the anesthetic drugs D. Produce less cardiovascular and respiratory suppression

A. Produce fast onset of anesthesia

A 25-year-old driver was held for reckless driving and confronting a policeman. He is too confident, talkatiye.restless and continuously walking around the hall. Which of the following is the drug that the driver is abusing? A. Diazepam B. Theophylline C. Amphetamine D. Lysergic acid diethylamide (LSD)

C. Amphetamine

Which of the following is a property of amphetamine? A. It does not cross the blood brain barrier B. It stimulates the release of stored acetylcholine C. It stimulates the release of stored norepinephrine D. It stimulates the release of five hydroxytryptophan (5-HT

C. It stimulates the release of stored norepinephrine

Which depolarizing neuromuscular blocker is less potent than tubocurarine? A. succinylcholine (Anectine) B. rocuronium (Zemuron) C. pipecuronium (Arduan) D. doxacurium (Nuromax)

A. succinylcholine (Anectine)

Which of the following is a consequence of stimulation of ꭤ1 - adrenoceptors? A. flushing B. increased heart rate C. constricted bronchioles D. elevated blood pressure

D. elevated blood pressure

Drug to reverse action of Atropine? A. Physostigmine B. Benztropine C. Disulfiram D. Propranolol

A. Physostigmine

Catechol amine with COMT ? A- rapid metabolism B- slow metabolism

A- rapid metabolism

What is the pharmacological classification of Ipratropium bromide? A. Beta agonist B. Alpha agonist C. Cholinergic agonist D. Antimuscarinic agent

D. Antimuscarinic agent

A 21-year-old patient went through respiratory depression after receiving anesthetic agent. Which of the following agents will counteract post-anesthetic respiratory depression? A. morphine B. picrotoxin C. diazepam D. thiopental

B. picrotoxin

Which of the following describes the mechanism of action of rivastigmine? A. cholinesterase inhibitor B. alpha-a receptor inhibitor C. serotonin reuptake inhibitor D. angiotensin converting enzyme inhibito

A. cholinesterase inhibitor

Which of the following drugs would decrease the amount of minimum alveolar concentration (MAC) for an anesthetic drug? A. diazepam B. buspirone C. ephedrine D. loratadine

A. diazepam

What is the antidote for heparin toxicity? A. Protamine sulfate B. Sodium salicylate C. Naloxone D. Glucagon

A. Protamine sulfate

Which of the following anesthetics drugs has a higher risk of causing anemia? A. propofol B. ketamine C. isoflurane D. nitrous oxide

D. nitrous oxide

Which of the following is heparin antidote? A. Protamine Sulphate B. Octreotide C. N-Acetylcysteine D. Naloxone Hydrochloride

A. Protamine Sulphate

11-A 55-year-old man presents with an excessive bronchial and oconasal secretions. History revealed, is exposed to an organophosphate insecticide. Which of the following is the best management? A. Atropine IV B. Diphenhydramine orally C. Pralidoxime intramuscularly D. Physostigmine intramuscularly

A. Atropine IV

In case a patient develops toxicity from midazolam. Which of the following medications can be given as an antidote? A. Atropine B. Flumazenil C. Amifostine D. Acetylcysteine

B. Flumazenil

Which of the following situation is most likely to be controlled by administering parenteral calcium as an antidote? A. Hypokalemia B. Verapamil overdose C. Heroine intoxication D. Cocaine intoxication

B. Verapamil overdose

Which of the following is the precursor for 5_hydroxytryptamine? A) proline B) alanine C) glutamine D) tryptophan

D) tryptophan

Which of the following enzymes regulate supercoiling of DNA? A) Helicases B) Primases C) Topoisomerases D) Reverse transcriptase

C) Topoisomerases

Where dose the electron transport chain reaction pathway take? A) Cell cytoplasm B) Golgi apparatus C) Outer mitochondrial membrane D) Inner mitochondrial membrane

D) Inner mitochondrial membrane

The diagram shows the role of a vitamin as coenzyme for cystathionine synthase and cystathionase enzymes which catalyze the transsulfuration of methionine to cysteine (see image). Which of the following is the vitamin indicated by the star* in the figure? A. B2 B. B3 C. B5 D. B6 number 50 page 8

Which of the following vitamin deficiency can cause scurvy? A. vitamin A B. vitamin B6 C. vitamin C D. Vitamin D

C. vitamin C

krebs cycle for production of ?

A- ATP

13-The synthesis of glycogen from glucose called?

A- Glycogenesis

Role of ATP ? A. Energy carrier B. Oxygen carrier C. Amino acid carrier

A. Energy carrier

pH difference between extracellular and intracellular fluid is A. Nil B. 0.2 C. 0.4 D. 0.8

C. 0.4

use Glucosamine for uses ?? A- Osteoporosis B- Osteomyelitis C- Osteoarthritis

C- Osteoarthritis

which is cytokine A. Leukotriene B. Adrenaline C. Gonadotropin

A. Leukotriene

Which Amino acid we give for anorexia? A. Alanine B. arginine C. valine

coenzyme for cystathionine synthase and cystathionase enzymes which catalyze the transfiguration of methionine to cysteine ? A- B2 B- B3 C- B5 D- B6

D- B6

Which process does Insulin work on increase? A- Glycogenolysis B- Glyconeogenesis C- Glucogensis D- Ketogenesis

B- Glyconeogenesis

Which process does Insulin work on or increase ? A. Glycogenolysis B. Glyconeogenesis C. Glucogensis D. Ketogenesis

B. Glyconeogenesis

How much molecule ATP molecules are produced for every glucose. A- 12 B- 24 C- 34

C- 34

Which of the following is the precursor for 5- hydrotryptamine (serotonin)? A. Proline B. Alanine C. Glutamine D. Tryptophan

Where dose the electron transport chain reaction A. pathway take B. Cell cytoplasm C. Golgi apparatus D. Outer mitochondrial membrane E. Inner mitochondrial membrane

E. Inner mitochondrial membrane

- starch is digested in saliva by ? A. Amylase B. lipase

DNA ligase enzyme for ligation of ? A. mRNA with TRNA B. 2mRNA molecules C. 2tRNA molecules D. 2DNA strands

D. 2DNA strands

POLYSACCHARIDE? A- Glucose b- glycogen c- glucagon

How much ATP molecules are produced for every glucose molecule? A. 12 B. 24 C. 34

How many amino acid in the human body ? A. 20 B. 30 C. 40

a. 20

Which parameter used when we give statin and there is rhatdomyolysis ? A- Creatine kinase B- Crcl

Which of the following is a non-essential amino acid? A) Lysine B) Valine C) Cysteine D) Isoleucine

C) Cysteine N.B. the 9 essential amino acids are : histidine, isoleucine, leucine, lysine, methionine ,phenylalanine, threonine, tryptophan and valine

Which of the following could lead to decrease in international normalization ratio (INR) in a patient of warfarin therapy? A. decrease the consumption of dietary vitamin K B. carbamazepine therapy C. cotrimoxazole therapy D. metronidazole therap

Purpose of mitochondria ? A- Synthesis of DNA B- Synthesis of RNA C- Produce ATP

C- Produce ATP

Which is complex protein ? A. Pr B. Sec C. Tri D. Quaternary in structure

D. Quaternary in structure

acetyl-CoA to form malonyl- coA which vitamine is used ? A. biotin (B7) B. riboflavin C. pyridoxine D. nicotinamide

A. biotin (B7)

Acetyl coA and cetric acid cycle which vitamine is used ? A. B6 B. B12 C. B2 D. B9

C. B2

What the function of small nuclear (snRNAs) in protein synthesis? A. Act as catalyst B. Modifies mRNA molecules C. Genetic blueprint for the protein D. Translates genetic code to amino acid

B. Modifies mRNA molecules

Which the carrier in Krebs Cycle? A. Carrier in cryps cycle B. oxaloacetat C. citric acid

B. oxaloacetat

which the Carbohydrates produce more energy A. glucose B. maltose C. sucrose

A. glucose

Number of ATP in glycolysis ? A- 1 B- 22 C- 24 D- 2

D- 2

Which of the following is the process of breaking down of glycogen ? A. Glycolysis B. Glycogenesis C. Glycogenolysis D. Gluconeogenesis

C. Glycogenolysis

Which of the following pairs represents the purines nitrogenous bases? A. Adenine (A) and Uracil (U) B. Cytosine (C) and Uracil (U) C. C)Adenine (A) and guanine (G) D. D)Cytosine (C) and guanine (G

C. C)Adenine (A) and guanine (G)

Which of the following inhibits gluconeogenesis? A. Insulin B. Glucagon C. Epinephrine D. Glucocorticodes

A. Insulin

which of the following inhibits gluconeogenesis A- insulin B- glucagon C- epinephrine D- glucocorticoids

Which of the following is a function of alcohol dehydrogenase enzyme? A. Accelerates the reduction of ethanol B. Accelerate the addition of hydrogen to ethanol C. Accelerates the addition of phosphate to ethanol D. Accelerates the removal of hydrogen from ethanol

D. Accelerates the removal of hydrogen from ethanol

A water-soluble vitamin catalyzes the carboxylation of acetyl-COA to form malonyl-CoA, which is required for the synthesis of fatty acids (see image) Which of the following vitamins plays this role? A. biotin (b7) B. riboflavin C. pyridoxine D. nicotinamide image number 84 page 12

which of the following anti platelets is contraindicated patients with transient ischemic attack (TIA) or stroke? A. Prasugrel B. Ticagrelor C. Clopidogrel

Which of the following compounds is urea cycle a biochemical reaction that produce urea from? A. Sucrose B. Glucose C. Glycogen D. Ammonia (NH3)

D. Ammonia (NH3)

Which of the following is an example of a parenteral direct thrombin inhibitor? A) enoxaparin B) argatroban C) fondaparinux D) unfractionated heparin

B) argatroban

Which of the following is a potential serious side effect that is common among all anticoagulant agents? A. Hypokalemia. B. Major Bleeding C. Liver Dysfunction D. Renal Dysfunction

B. Major Bleeding

which of the following antiplatelet agents the highest risk of causing dyspnea ? A. Prasugrel B. Ticagrelor C. Clopidogrel D. Dipyridamole

Which of the following enzymes is responsible for forming DNA copy from RNA? A. Reverse transcriptase B. DNA polymerase C. Helicase D. Primase

A. Reverse transcriptase

A 51-year-old man diagnosed with pulmonary embolism. The patient planned for warfarin and started combination with warfarin until INR is therapeutic (see lab result) weight :80kg height : 160 cm test:creatine result: 85 normal value: 44-115 umol/L test: creatinin clearance result: 103 normal value: 70-103 umol/L Which of the following enoxaparin dose regimen should the patient receive? A. Enoxaparin 30 mg SC every 24h B. Enoxaparin 40 mg SC every 24h C. Enoxaparin 80 mg SC every 12h D. Enoxaparin 160 mg SC every 12h

C. Enoxaparin 80 mg SC every 12h

Which of the following medications is an anticoagulant agent? A. Aspirin B. Warfain C. Clopidogrel D. D. Streptokinase

B. Warfain

Which of the following medications produces antiplatelet effect by inhibiting Adenosine Diphosphate (ADP) receptors? A. aspirin B. abciximab C. clopidogrel D. streptokinase

C. clopidogrel

Which of the following drugs can be used to lyse fibrin clots? A. heparin B. warfarin C. enoxaparin D. streptokinase

D. streptokinase

Which of the following is the recommended anti-coagulation strategy for atrial fibrillation patient with a CHA2DS2-VACS score of 5? A. aspirin B. dabigatran C. clopidogrel D. no anticoagulation

Which of the following is the mechanism of action of apixaban? A. an indirect inhibitor of thrombin B. an indirect inhibitor of factor Xa C. a direct inhibitor of thrombin D. a direct inhibitor of factor Xa

D. a direct inhibitor of factor Xa

Which of the following is a potential serious side effect that is common among all anticoagulant agents? A. hypokalemia B. major bleeding C. liver dysfunction D. renal dysfunction

B. major bleeding

Which of the following is the preferred anticoagulant therapy during hemodialysis procedure? A. Enoxaparin B. Dabigatran C. Rivaroxaban D. Unfractionated heparin (UFH)

D. Unfractionated heparin (UFH)

Which of the following can decrease the effect of warfarin? A. Antibiotics B. Paracetamol C. Multivitamins (contain vit k) D. Calcium supplement

C. Multivitamins (contain vit k)

What is the route of administration of Enoxaparin? A. Intrathecal bolus B. Transdermal injection C. Subcutaneous injection D. Intramuscular injection

C. Subcutaneous injection

Which of the following best represents the activity of dipyridamole? A. It has fibrinolytic activity B. It has antifibrinolytic activity C. It is a platelet aggregation inhibitor D. It is a phosphodiesterase enzyme induce

C. It is a platelet aggregation inhibitor

Which of the following is recommended regarding air bubble in the syringe for a patient starting on enoxaparin subcutaneous Injection? A. inject the dose with the air bubble B. Inject the air bubble if the volume is small C. remove the air bubble to avoid wastage of the dose D. remove air bubble and adjust volume before injection

A. inject the dose with the air bubble

D. a direct inhibitor of factor Xa

Which of the following can decrease the effect of warfarin? A. antibiotics B. paracetamol C. multivitamins D. calcium supplement

C. multivitamins

What is the route of administration of Enoxaparin? A. Intrathecal bolus B. Transdermal injection C. Subcutaneous injection D. Intramuscular injection

C. Subcutaneous injection

Which of the following can decrease the effect of warfarin? A. Antibiotics B. Paracetamol C. Multivitamins (contain vit k) D. Calcium supplemen

C. Multivitamins (contain vit k)

Which of the following statements describes unfractionated heparin? A. enolic acid derivative B. propionic acid derivative C. acetyl ester of salicylic acid D. mucopolysaccharide polymer

D. mucopolysaccharide polymer

C. It is a platelet aggregation inhibitor

Which of the following medications is an anticoagulant agent? A. Aspirin B. Warfain C. Clopidogrel D. D. Streptokinase

B. Warfain

Which of the following drugs can be used to lyse fibrin clots? A. heparin B. warfarin C. enoxaparin D. streptokinase

D. streptokinase

Which of the following can decrease the effect of warfarin? A. antibiotics B. paracetamol C. multivitamins D. calcium supplement

C. multivitamins

Which of the following medications produces antiplatelet effect by inhibiting Adenosine Diphosphate (ADP) receptors? A. aspirin B. abciximab C. clopidogrel D. streptokinase

C. clopidogrel

Which of the following is parenteral direct thrombin inhibitor? A. Argatroban B. Dabigatran (ORAL ) C. Heparin D. Warfarin

A. Argatroban

Risk factor cause DVT? A. Age B. food rich of VK C. surgery

C. surgery

Which of the following is recommended regarding air bubble in the syringe for a patient starting on enoxaparin subcutaneous injection? A. Inject the dose with the air bubble B. inject the air bubble if the volume is small C. remove air bubble to avoid wastage of the dose D. remove air bubble and adjust volume before injection

A. Inject the dose with the air bubble

how ibuprofen inhibit antiplatelet effect of aspirin

A- Ibuprofen bind to cox1 and hinder it's acetylation by aspirin

The recommended DVT prophylaxis dose for postpartum in women with heigh risk of DVT is? A. 3 weeks B. 6 weeks C. 3 months D. 6 months

B. 6 weeks

Neonate with coagulopathy which vit K route will you use ? A. Suppository B. Iv C. Sc D. Im

b. IV child is IM Coagulopathy.. IV

- Which of the following antiplatelet working by inhibition of adenosine diphosphate receptor? A. Aspirin B. Abciximab C. Clopidogrel D. Streptokinase

C. Clopidogrel

Which direct anticoagulant needs premedication 5-10 days with anticoagulant ? A. Apixaban B. Dabigatran

B. Dabigatran

patient on warfarin and has mechanical valve and INR 3.5, what should you do ? A- No management b- decrease warfarin dose

A- No management

antiplatelet C.I. in patients with transient ischemic attack ? A- dipyradimole B- clopidogrel C- prasugrel D- ticagrelor

C- prasugrel

INR monitoring after initiation as outpatient ? A- next day B- 2-5 days C- 1 month D- 3 months

B- 2-5 days

treatments of pulmonary embolism? A- Enoxaparin 40 mg sc once daily B- Rivaroxaban C- Enoxaparin 1 mg/ kg twice daily Or 2 mg/ kg once daily

C- Enoxaparin 1 mg/ kg twice daily Or 2 mg/ kg once daily

patient is taking warfarin 4.5 mg PO daily came to the clinic with INR of 5.1 without any signs of active bleeding, what is the appropriate management for her ? A. Hold warfarin and give vit K IV B. Hold warfarin and resume with lower dose C. Hold warfarin and give platelet

B. Hold warfarin and resume with lower dose

in pregnancy what the trimester can be use warfarin ? A. first B. second C. third trimester D. avoided use in pregnancy

D. avoided use in pregnancy

Pt use Warfarin 10mg and INR low why ? A. Low dose B. Dite C. Low bioavailability of warfarin

B. Dite

which the fallowing uses in prophylaxis strock A. anticoagulant B. thrombolytic drug C. antipletalate

C. antipletalate

Which the fallowing drugs inducing thrombocytopenia A- UFH heparin B- LMWH C- warfarin D- Aspirin

A- UFH heparin

Which the fallowing drugs treatment thrombocytopenia A- UFH B- LMWH C- warfarin D- Argatroban

D- Argatroban

Medication for osteoporosis in menopausal women given monthly? A. Zoledronic acid B. ibandronate C. raloxifene

B. ibandronate

Medication for osteoporosis in women given weekly ? A- Zoledronic acid B- ibandronate C- raloxifene D- Alendronate

D- Alendronate

gold standard test for Osteoporosis ?

A- (DEXA) ✅ dual-energy x-ray absorptiometry

285- Patient with Osteoporosis which need for Diagnosis? A- X-ray B- MRI C- CT

A- X-ray

Which of the following osteoporosis drugs can cause esophageal ulcers? A. denosumab B. teriparatide C. alendronate D. zelodronic acid

C. alendronate

Which of the following medications for osteoporosis will significantly reduce the risk of hip fracture? A. Phosphate B. Risedronate C. Raloxifene D. Calcitonin

B. Risedronate

A 65-year patient suffered from Osteomalacia with finger numbness, tingling and burning of extremities. The doctor prescribed vitamin D and an IV calcium supplement. Which of the following calcium salts did the physician most likely prescribed ? A. Calcium citrate (21%calcium) B. Calcium lactate(13%calcium) C. Calcium gluconate (9%calcium) D. Calcium phosphate (39% calcium)

C. Calcium gluconate (9%calcium) N.B:-Ca phosphate no more effective — and may in fact be less effective — than calcium citrate or calcium carbonate

A 6-year-old child weighing 28 kg came to the clinic with viral infection. The physician prescribed acyclovir at a dose of 20 mg/kg four times a day. Acyclovir is available as 200 mg/5 ml oral suspension. How many milliliters would be administered per day? A. 10 B. 14 C. 44 D. 56

D. 56

A physician prescribed heparin at a dose of 75 units/Kg every six hours for a child weighing 15 kg, heparin is available in 2.5 ml vial containing 12,500 units. How many milliliters of heparin solution would be administered every day? A. 0.5 B. 0.9 C. 1.5 D. 1.8

B. 0.9

The following formula was prescribed by a dermatologist for a patient with dermatitis. Hydrocortisone 1.5% w/w Cream base to make 50g the pharmacist has two strengths of hydrocortisone creams in his hand, 2.5% and 1%. Therefore, in order to compound this prescription, the pharmacist is going to add these two creams strength together in certain proportions to fulfill this formulation. Which of the following is the weight ratio of the two strengths of hydrocortisone needed? A. 1:2 B. 1:1 C. 0.5:1 D. 2:1

C. 0.5:1

The pharmacist received a prescription to extemporaneously prepare moxifloxacin oral suspension from the 400 mg tablet in a concentration of 20 mg/ml with total volume of 60 mL Which of the following is the number of tablets of moxiflaxacin 400 mg needed to prepare the above prescription? A. 2 B. 3 C. 4 D. 6

B. 3

Drug X has an infusion rate of 0.95 mg/kg/hr. Which of the following is the amount of drug X (in mg) needed for a 12- hr infusion if patient weight is 70 kg? A. 66.5 mg B. 84 mg C. 665 mg D. 798 mg

D. 798 mg

D. 56

A patient is to receive one mg of hydromorphine hydrochloride injection for pain. Hydromrophine hydrochloride is available as 500 mg in a 50 ml vial. How many milliliters would be injected? A. 0.1 B. 0.5 C. 1.0 D. 2.0

A. 0.1

A solution contains 2.5 mg of a drug per milliliter. administered at a rate of 50 mg/hr. (1 ml = 30 drops). Which of the following Is the most appropriate infusion rate? A) 5 drops/min B) 10 drops/min C) 20 drops/min D) 40 drops/min

B) 10 drops/min

A 2.5% intravenous drug is infused at a rate of 1.5 ml/min. Which of the amount of the drug (in mg) that is infused in each hour? A) 25 B) 225 C) 2000 D) 2250

D) 2250

-A technician is preparing 250 ml of 70% (w/v) dextrose solution. Which of the following is the total amount of dextrose (in grams) in the final preparation? A) 125 g B) 150 g C) 175g D) 200 g

C) 175g

How many milliliters of paracetamol syrup of 120 mg/5 ml strength would be prepared using 1.8 kg of paracetamol? A) 15,000 mL B) 30,000 mL C) 50,000 mL D) 75,000 mL

D) 75,000 mL

What is the percentage w/v of 10 ml vial that contains 50 mEq of ammonium chloride per 10 ml if 1 mEq of ammonium chloride = 0.0535g? A) 0.535 B) 2.675 C) 5.350 D) 26.750

B) 2.675

One folic acid tablet contains 400 mcg of folic acid as an active ingredient. How many tablets would be required for the preparation of 30 grams of folic acid? A) 5000 tablets B) 7500 tablets C) 50000 tablets Đ) 75000 tablets

Đ) 75000 tablets

A 6-year-old HIV infected boy measuring 0.9 m2 is to receive nevirapine 140 mg/m' two times daily. Nevirapine is available as 50 mg/5 ml suspension. How many millilters of nevirapine suspension would be administered per dose? A) 6.3 B) 12.6 C)14.0 D) 16.5

B) 12.6

A drug has a clearance value of 4.75 L/hour and 65% is cleared by renal excretion. Which of the following would be the non-renal clearance value? A) 1.25 L/hrs B) 1.66 L/hrs C) 1.90 L/hrs D) 2.05 L/hr

B) 1.66 L/hrs

A patient is to receive 400 ml intravenous infusion of a 1% drug that will be over 10 hours Which of the following is the amount (milligrams)of the drug that will be delivered in 15 minutes ? A) 100 mg B) 150 mg C) 200 mg D) 400 mg

A) 100 mg

Penicillin-G potassium Is available in 50 ml vial containing 20 gram. Each milligram of penicillin-G potasslum is equal to 1500 units. How many units of penicillin G potassium are there in each vial? A) 15,000,000 B) 20,000,000 C) 25,000,000 D) 30,000,000

D) 30,000,000

A physician prescribes, for a 6-year-old child 10 mg, omeprazole daily for seven days as a syrup formulation. Omeprazóle capsules strength are available in the pharmacy is 10 mg Which of the following is the number of capsules required to make to suffice the total doses in the prescription if the final concentration syrup should be 2 mg/mL? A) 2 B) 3 C) 5 D) 7

D) 7

A 35-year-old individual is receiving 20 mg of propranolol hydro four times daily as a prophylaxis to migraine attacks. The drug 25% bioavailability due to extensive first pass effect. What amount of the drug reaches the systemic circulation after dosing? A) 2.5 mg B) 5.0 mg C) 7.5 mg D)10mg

B) 5.0 mg

A 55-year-old man with a history of recurrent back pain is admitted to the hospital, he was prescribed paracetamol 1000 mg P.O Q6hr PRN for 1-month available tablet is 500mg. What is the maximum quantity given for a refill? A. 8 tablets B. 24 tablets C. 42 tablets D. 240 tablets

D. 240 tablets

-A child weighing 25 kg is prescribed acetazolamide 2.5 mg/kg every 12 hours. Acetazolamide is available in a liquid dosage form with strength of 25 mg/ml. How many milliliters would the patient be administered per dose? A. 2.5 B. 5.0 C. 7.5 D. 10

A. 2.5

The diclophenac sodium suppository is prepared according to the following formula: Diclophenac sodium 2.5% Triglyceride base to make 1g How many grams of diclophenac sodium should be used to prepare 24000 suppositories? A. 120 B. 240 C. 480 D. 600

D. 600

Which of the following is the amount of dextrose (in grams) that is present in 100 ml of 10% dextrose solution? A. 1 B. 10 C. 100 D. 1000

B. 10

a 4-year-old boy is admitted with dehydration. he is started on dextrose 5% and normal saline with 40 milliequivalent potassium chloride per liter at a rate of 40 ml per hour weight is 16 kilograms. How much potassium chloride (in milliequivalent per kilograms per day) is her receiving? A. 2.4 B. 3 C. 4.5 D. 6

A. 2.4

which of the following is the percentage (%) strength of ketorolac tromethamine in an ophthalmic solution if 200 micrograms of the drug are present in 50 microliters of the solution? A. 0.25 B. 0.40 C. 0.50

B. 0.40

10 ml vial contains 1 gm of clindamycin hydrochloride. each milligram of clindamycin hydrochloride is equivalent to 800 micrograms (mcg) of clindamycin. How much clindamycin in micrograms (mcg) is present in 3 ml solution? A. 240 B. 2,400 C. 24,000 D. 240,000

D. 240,000

A solution contains 27 mg of antipyrine per 500 microliter. How many grams of antipyrine are there in 3 ml of the solution? A. 0.162 gm B. 0.270 gm C. 162 gm D. 270 gm

A. 0.162 gm

A 5-years-old girl weights 16 kilograms and is 95 centimeters tall. Which of the following is her body surface area in squared meter (m)? A. 0.1 B. 0.4 C. 0.6 D. 0.9

C. 0.6

he following prescription is received in a hospital pharmacy: Losartan 25 mg S: Take 1 tab BID M: 3 weeks Which of the following instructions will be on the prescription label? A. Take 1 tablet once daily (21 tablets) B. Take 2 tablets once daily (42 tablets) C. Take 1 tablet twice daily (42 tablets) D. Take 2 tablets twice daily (48 tablets)

C. Take 1 tablet twice daily (42 tablets)

How many milliliters are there in one table spoonful in a metric system? A. 2.5 ml B. 5.0 ml C. 10 ml D. 15 ml

D. 15 ml

A solution contains 2.5 mg of a drug per milliliter. The drug is to be administered at a rate of 50 mg/hr. (1 mL= 30 drops). Which of the following is the most appropriate infusion rate? A. 5 drops/min B. 10 drops/min C. 20 drops/min D. 40 drops/min

B. 10 drops/min

A patient is to receive two drops of dexamethasone four times daily. The dexamethasone is available as 0.1% solution in a 5 ml bottle with a dropper calibrated to deliver 16 drop per ml. How many days will the bottle last? A. 4 B. 6 C. 8 D. 10

D. 10

What is the specific gravity of a liquid if 121.92 ml of its weight is 107.56 g? A. 0.882 s.g. B. 1.88 s.g. C. 2.88 s.g. D. 8.822 s.g.

A. 0.882 s.g.

- A physician prescribed 5000 units of heparin two times daily for five days. Heparin is available in a vial containing 20,000 units/ml. How many milliliters should be given for each dose? A. 0.25 B. 0.50 C. 0.75 D. 1.50

A. 0.25

A solution contains 5 gm of drug per 25 ml. Which of the following is the concentration, in mg/ml, of the drug? A. 50 mg/ml B. 100 mg/ml C. 200 mg/ml D. 400 mg/ml

C. 200 mg/ml

-A 20-year-old boy who weighs 10 kg is prescribed Drug x as 1 mg/kg/hour infusion, The pharmacy prepared the prescription by diluting 5 ml of 25 mg/ml concentration via to100 ml with normal saline. Which of the following is the rate of infusion (in ml/hour) A. 2 B. 4 C. 6 D. 8

D. 8

A drug has a total body clearance of 2.5 L/hr. Its hepatic metabolism accounts for 25% during less blood perfusion and 40 % when blood perfusion is higher to the liver. What will be the hepatic clearance value in fed state of stomach? A. 0.50 L/hr B. 0.75 L/hr C. 1.00 L/hr D. 1.50 L/hr

C. 1.00 L/hr

2-A physician ordered Labetalol hydrochloride intravenous infusion at a close of 500 micrograms/min over an hour for a hypertensive patient. Labetalol hydrochloride is available in a 20 ml vial containing 5 mg/ml of the drug. Which of the following is the amount in (milliliters) of labetalol hydrochloride solution that should be administered? A. 4.5 B. 6 C. 7.5 D. 10

B. 6

An ointment was prepared by incorporating 15 g of a drug into 150 g of petrolatum. What would be the concentration of the drug in the ointment? A. 0.91% B. 1.00% C. 0.10% D. 10.00%

D. 10.00%

A 2.5%intravenous drug is infused at a rate of 1.5 m/min Which of the amount of the drug (in mg) that is infused in each hour? A. 25 mg B. 225 mg C. 2000 mg D. 2250 mg

D. 2250 mg

If a pharmacist has a stock solution of D5W and D50W How many milliliters form each solution will need in order to prepare a 450 ml of D15W solution? A. D50w/ D5w=100/350 B. D50w/D5w=350/100 C. D50w/D5W=200/250 D. D50w/D5w= 250/200

A. D50w/ D5w=100/350

How much of 5% w/v solution would be required to prepare 60 ml of 5mg/ml solution? A. 6 ml B. 10 ml C. 15 ml D. 18 ml

A. 6 ml

The pharmacy receives a prescription for labetalol 800 mg twice daily for three days. The available strength of labetalol in the pharmacy is 200 mg. Which of the following is the number of 200 mg labetalol tablet needed to prepare the above prescriptions for the total duration? A. 8 B. 12 C. 16 D. 24

D. 24

A drug vial contains 0.2% of drug x. Which of the following is the amount of the drug x (in mg) in a 5ml dose? A. 0.1 B. 1 C. 10 D. 100

A patient is to receive 25 mg of dextromethorphan four times daily for cough. The pharmacist dispensed two 125 ml bottles containing 10 mg of dextromethorphan per 5 ml. How many days will the two bottles last? A. 3 B. 5 C. 7 D. 9

A hospitalized patient with hypertension is prescribed nicardipine hydrochloride intravenous infusion at a dose of 5 mg per hour for four hours. Nicardipine hydrochloride is available as a 10 ml vial containing 25 mg of nicardipine hydrochloride. How many milliliters of nicardipine should be used? A. 2.5 B. 4.0 C. 8.0 D. 10.0

A 100 mL infusion bottle contains 2 g of potassium chloride (KCI). (Mol.wt.kcl= 74.6). Which of the following is the most likely amount of KCL present in the infusion bottle? A. 12.7 mEq B. 20 mEq C. 26.8 mEq D. 78.5 mEg

Heparin is prepared in a piggy-bag which contains 25,000 units in 250 ml. How many milliliters of heparin per hour must be given to a 70-kilogram male patient if infusion rate is 10 units\kg\hour? A. 5 ml B.7 ml C. 10 ml D. 20 ml

What is the weight of 60 ml olive oil (density: 0.92 g\ml)? A. 36.66 gm B. 49.60 gm C. 55.20 gm D. 65.86 gm

How many grams of water are needed to make 100grams of 5% (W\W) solution of potassium acetate? A. 57 g B. 95g ممكن C. 115 g D. 140

A patient is prescribed 0.25% alcaftadine ophthalmic solution, one drop for each eye per day. Alcaftadine is available in a 3 ml bottle and one ml contains 14 drops. How many days will the bottle last? A. 6 B. 13 C. 17 D. 21

A500 infusion bottle contains 11.72 g of potassium chloride (kCI). The molecular weight of KCI= 74.6 grams. Which of the following is the amount of KCI, in milliequivalent (mEq), present in the bottle? A. 0.637 mEq B. 6.37 mEq C. 11.72mEq D. 157.1 mEq

A 65-year-old man (weight=70 kg) with acute decompensated heart failure is to be started on dobutamine 5 mcg\kg\ minute. The infusion bag contains dobutamine 150 mg in 100 ml of 0.9% sodium chloride. He has normal renal function. Which of the following is the rate of infusion of dobutamine? A. 0.25 mL\hour B. 1.3 mL\hour C. 14 mL\hour D. 26 mL\hour

A 6-year-old HIV infected boy measuring o.9 m2 is to receive nevirapine 140 mg\m2 two times daily. Nevirapine is available as 50 mg\5 ml suspension. How many milliliters of nevirapine suspension would be administered per dose? A. 6.3 B. 12.6 C. 14.0 D. 16.5

A patient is to receive 750 ml 5% dextrose over five hours. The intravenous infusion set delivers 10 drops\ ml. Which of the following is the flow rate in ml\min to deliver the prescribed volume? A. 1.5 B. 2.0 C. 2.5

A pharmacist calculates a dose of 500 µg/min for continuous infusion of dopamine based on weight of the patient. The concentration of a premixed dopamine infusion is 400 mg/250 ml. What is the most likely amount of dopamine in ml received by the patient in the first hour of treatment? A. 10 ml B. 19 ml C. 24 ml D. 28 ml

A drug was given to a patient with a constant intravenous infusion rate of 10 mg/hour. The half-life of the drug is three hours. Which of the following is the time in hours to reach steady state plasma concentration? A. 10 B. 15 C. 20 D. 30

A syrup is 70% w/v solution of sucrose in water. How much of sucrose is required to prepare 500 ml of this syrup? A. 250 g B. 300 g C. 350 g D. 400 g

Lidocaine is commonly administered for patient exhibiting cardiac arrhythmias. Lidocaine pharmacokinetic parameters are as follows half- life = 2 hours, clearance = 9 mL/min/kg and volume of distribution = 70 L. Which of the following is the time (in hours) needed to achieve 87.5% of the steady state concentration in a 70-kg individual? A. 2 B. 4 C. 6 D. 8

A 9-year-old child weighing 36 kg came to the clinic with chickenpox. The physician prescribed acyclovir at a dose of 20 mg/kg four times a day for five days. Acyclovir is available as 200 mg/5ml oral suspension. How many milliliters of suspension should be dispensed? A. 240 B. 320 C. 360 D. 540

How many grams of dextrose are in a 250 ml bag of 10% dextrose? A. 12.5 B. 25 C. 50 D. 100

A water sample contains 9 ppm of magnesium. Which of the following is the percentage of magnesium in this sample? A. 0.9% B. 0.09% C. 0.009% D. 0.0009%

Results data from a bioavailability study of four different dosage forms of an antibiotic drug is shown (see table). DRUG DOSAGE FORM:IV SOLUATION DOSE (MG/KG):0.2 CUMLATIVE URINARY FROM DRUG EXCREATION 0-72 H:20 DRUG DOSAGE FORM:ORAL SOLUTION DOSE (MG/KG):4 CUMLATIVE URINARY FROM DRUG EXCREATION 0-72 H:380 DRUG DOSAGE FORM:ORAL TABLET DOSE (MG/KG):4 CUMLATIVE URINARY FROM DRUG EXCREATION 0-72 H:340 DRUG DOSAGE FORM:ORAL TABLET DOSE (MG/KG):4 CUMLATIVE URINARY FROM DRUG EXCREATION 0-72 H:360 The volunteers fasted for 12 hours prior to taking the drug products. Urine samples were collected up to 72 hours after the administration of the drug to obtain the maximum urinary drug excretion. Which of the following is the absolute bioavailability of the tablet dosage form? A. 80% B. 85% C. 90% D. 95% B

Which of the following is the expected bioavailability (F) of drugs given by intravenous route? A. less than 25% B. 25%-50% C. 75% -100% D. 100%

A patient presents a prescription with the following antiviral regimen. Start with 50 mg then decrease by 10 mg every 2 days until finished. Which of the following quantities of 5 mg tablets is needed to fill this prescription? A. 20 B. 30 C. 40 D. 60

Which of the following is the calculation of the apparent volume of distribution if the patient received 400 mg of intravenous medication that produced immediate blood concentration of 10 microgram/ml? A. 0.025 L B. 0.4 L C. 25 L D. 40L

-A solution contains 2.5 mg of a drug per milliliter. The drug is to be administered at a rate of 50 mg/hr. (1 mL=30 drops). Which of the following is the most appropriate infusion rate? A. 5 drops/min B. 10 drops/min C. 20 drops/min D. 40 drops/min

A 20 ml vial of penicillin-G potassium containing 2,000,000 units is available. Each mg of the drug is equivalent to 1600 units. How many milligrams of penicillin-G potassium are there in one ml of the solution? A. 12.50 B. 62.50 C. 160 D. 1250

-A drug vial contains 0.2% of drug X. Which of the following is the amount of the drug X (in mg) in a 10 ml dose? A. 0.1 B. 1 C. 10 D.20

The vitamin-D solution is available in a 2.5 ml bottle containing 36,000 international units. The recommended daily dose for children is 400 international units. Each ml of vitamin D solution contains 36 drops. How many drops should be administered to a child per day? A.1 B.2 C. 4 D. 12

A pharmacist adds 2 g of potassium chloride to 1L of D5W/1/2 normal saline. Atomic welghts (see table). Sodium 23 Potassium 39 Chloride 35.5 Dextrose 198

Which of the following is the most likely osmolality of solution assuming the final volume as 1 L? A. 54 mosm/L B. 300 mosm/L C. 405 mosm/L D. 460 mosm/L

A budesonide inhaler delivers 200 puffs and each puff contains 100 micrograms of the drug. Which of the following is the amount (in milligrams) of total budesonide present in the inhaler? A. 10 mg B. 20 mg C. 10,000 mg D. 20,000 mg

A 5OO infusion bottle contains 11.72g of potassium chloride (KCI). The molecular weight of KCL 74.6 grams. Which of the following is the amount of KCL in milliequivalent (mEq). present in the bottle? A. 0. 637 mEq B. 6.37 mEq C. 11.72 mEq D. 157.1 mEq

A 500-mg dose of aspirin was given Intravenously to a patient produced an initial plasma concentration of 100 mg/L. If the half-life of the drug is 6.93 hours, what would be the total body clearance? A. 50 Liters/hour B. 10Liters/hour C. 5Liters/hour D. 0.5 Liters/hour

-A 500-mg dose of aspirin was given Intravenously to a patient produced an initial plasma concentration of 100 mg/L. If the half-life of the drug is 6.93 hours, what would be the total body clearance? A. 50 Liters/hour B. 10Liters/hour C. 5Liters/hour D. 0.5 Liters/hour

How many grams of 5% diclofenac cream should be mixed with 100 g of 1% cream to make a 2.5% diclofenac cream? A. 30 g B. 60 g C. 90 g D. 120 g

If multivitamin syrup contains 150 IU of vitamin A in each milliliter. Which of the following quantities of international units of vitamin A would be provided by 1 teaspoonful? A. 500 B. 750 C. 1000 D. 2250

Penicillin-G potassium is available in 50 ml vial containing 20 grams. Each milligram of penicillin-G potassium is equal to 1500 units. How many units of penicillin G potassium are there in each vial? A. 15,000,000 B. 20,000,000 C. 25,000,000 D. 30,000,000

A physician ordered Labetalol hydrochloride intravenous infusion at a dose of 500 micrograms/min over an hour for a hypertensive patient. Labetalol hydrochloride is available in a 20 ml vial containing 5 mg/ml of the drug. Which of the following is the amount in (milliliters) of labetalol hydrochloride solution that should be administered? A. 4.5 B. 6 C. 7.5 D. 10

A solution contains 448 mg of KCI (MW=74.5) and 468 mg of NaCl (MW=58.5) in 500 ml. Which of the following is the osmolar concentration of this solution? A. 0.056 B. 0.065 C. 1.556 D. 1.256

A 10 ml ampule of 0.25% nicardipine hydrochloride is given to a patient after prepared diluted with 5% dextrose to get the drug concentration of .1mg/ml. How many milliliters of 5% dextrose should be used? A. 25 B. 100 C. 240 D. 250

A drug vial contains 0.4% of drug X. Which of the following is the amount of the drug X (in mg) in a 5 ml dose? A. 0.2 B. 2 C. 20 D. 200

A patient is prescribed 15 mg of paclitaxel by intravenous infusion. Paclitaxel is added to 150 ml 5% dextrose solution. The infusion was given over two hours. Which of the following is the infusion rate? A. 0.75 ml/min B. 1.25 ml/min C. 1.75 ml/min D. 2.50 ml/min

An elixir contains 5 mg of drug X per ml. Which of the following is the amount of the elixir (in micrograms) in one teaspoon dose? A. 0.5 B. 1000 C. 1500 D. 25000

A patient is receiving an intravenous infusion of theophylline at a rate of 0.48 mg/min. The average population pharmacokinetic parameters of theophylline are as follow: volume of distribution=95 Liter, renal clearance 48 mL/min, and elimination half-life= 8 hours Which of the following is the time (in hours) needed to achieve 93.75% of the final steady-state concentration? A. 8 B. 12 C. 24 D. 32

A 4-year-old boy is admitted with dehydration. He is started on Dextrose 5% and normal saline with 40 milliequivalents potassium chloride per liter at a rate of 40 ml per hour. His weight is 16 kilograms. How much potassium chloride (in milli equivalent per kilogram per day) is her receiving? A. 2.4 B. 3 C. 4.5 D. 6

ltarol tablets contain 25 mg of Diclofenac Sodium. Molecular formula of Diclofenac Sodium: C14H10Cl2NO2.NA (see table). Relative atomic mass Carbone 12.1 Hydrogen 1.008 Chloride 34.45 Nitrogen 14.01 Sodium 22.99 Oxygen 16.00 What is the amount of diclofenac per tablet of Voltarol? A. 20.99 B. 21.98 C. 23.19 D. 24.27

A drug X is available in 100 mg/5 ml bottle. A prescription calls for: Drug X 200 mg three times daily for 7 days. How many (ml) are needed for the five days? A. 7.5 B. 15 C. 75 D. 150

A drug was given to a patient with a constant intravenous infusion rate of 10 mg /hour. The half-life of the drug is three hours. Which of the following is the time in hours to reach steady state plasma concentration? A. 10 B. 15 C. 20 D. 30

A pharmacy intern is preparing a solution containing 8.4 g of drug from an available stock solution labeled as 20% w/v. Which of the following is the volume he must take from 20% w/v solution? A. 4.2 mL B. 8.4 mL C. 42 mL D. 84 mL

A prescription order asks for compounding dimenhydrinate syrup of strength of 12.5 mg/5 mL. How many 50 mg tablets of dimenhydrinate is needed to prepare a 60 mL of the syrup? A. 1 B. 2 C. 3 D. 6

The weekly dose of docetaxel is 40 mg/m2 . How milliliters of docetaxel solution, 160 mg/16 ml would a patient measuring 1.5 m2 need every week? A. 4 ml B. 6 ml C. 8 ml D. 10 ml

A drug vial contains 0.2% of drug X. Which of the following is the amount of the drug X (in mg) in a 5 ml dose? A. 0.1 B. 1 C. 10 D. 100

A 1 milliequivalent of calcium chloride =0.0735 g. How many milliequivalents (Eq) of calcium chloride are there In a 10 ml vail containing 10 % calcium gluconate? A. 1.36 mEq B. 13.6 mEq C. 73.5 mEq D. 136.0 mEq

A 1 milli equivalent (1 mEq) of calcium gluconate = 0.215 g. How many milli equivalents (mEq) per ml of calcium gluconate are there in a 50 ml vial containing 5 g of calcium gluconate? A. 0.465 mEq/ml B. 2.320 mEq/ml C. 23.250 mEq/ml D. 46.500 mEq/m

A 10 ml ampule of 0.25 % nicardipine hydrochloride is given to a patient after proper diluted with 5 % dextrose to get the drug concentration of 0.1 mg/ml. How many milliliters of 5 % dextrose should be used? A. 25 B. 100 C. 240 D. 250

A preparation used 0.06 grams of drug X to prepare 120 tablets. Which of the following is the amount of the drug (in micrograms) in each tablet? A. 0.5 B. 5 C. 50 D. 500

A 50 year-old girl weighing 20 kg is brought to the clinic with Lyme disease. The physician prescribed cefuroxime 12.5 mg/ kg twice daily for 14 days. The pharmacist has cefuroxime powder for suspension which after reconstitution with water forms 100 ml suspension with concentration of 125 mg 5 ml. How many bottles would the pharmacist dispense? A. 1 B. 2 C. 3 D. 4

A child weighing 25 kg is prescribed acetazolamide 2.5 mg/kg every 12 hours. Acetazolamide is available in a liquid dosage form with strength of 25 mg/ ml. How many milliliters would the patient be administered per dose? A. 2.5 B. 5.0 C. 7.5 D. 10

Which of the following is the amount of a drug (in gm) that is needed to make 150 ml of a solution if each teaspoonful must contain 7.5 mg of the drug? A. 0.225 B. 0.75 C. 2.25 D. 7.50

-A Young child weight =30 kg) diagnosed with pharyngitis has been prescribed Augmentin suspension (125 mg amoxicillin/31.25 mg clavulanate/ 5 ml) days. to be given as two teaspoons three times daily for five . Which of the following is the minimum suspension volume that should dispense? A. 60 mL B. 90 mL C. 120 ml D. 150 mL

A25 ml solution contains 5 grams of the drug. Which of the following is the drug concentration in mg/ml in the solution? A. 50 mg/ml B. 100 mg/ml C. 200 mg/ml D. 400 mg /ml

A 1000-mg dose of a drug was given intravenously to a 25-year-old male patient weighing 60 Kg. the initial plasma concentration of the drug was found to be 10 mg/L, and the elimination rate constant was 0.1 h. Assuming linear kinetics, what would be the total body clearance? A. 10 litres/hour B. B.100 liters/hour C. 150 liters/ hour D. 250 litres/hour

1g dextrose kcal ? A- 3 B- 3.4 C- 4

A manufacturer wishes to produce a batch of compressed tablets each containing 800 mg active ingredient, with a mean table weight of 1.2 g. Which of the following is the weight of active ingredient that will be required for a total batch size of 720 kg ? A. 600 Kg B. 480 Kg C. 250 Kg

B 720 * 800 ÷ 1200 = 480

10 ml ampule of 0.25% nicardipine hydrochloride is given to a patient after proper diluted with 5% dextrose to get the drug concentration of 0.1 mg/ml. How many milliliter of $% dextrose should be used? A- 25 B- 100 c- 240 d-250

The pharmacy receive a prescription for 7% Beclomethasone ointment 100g in the pharmacy you have 2% ointment, and 10% ointment. Using the alligation method, calculate how much you need of the 2% ointment, and 10% ointment to make the 7% ointment required. A- How much 10% ointment (in grams) b- How much 2% ointment (in grams)

drug has volume of distribution 15 liter and oral bioavailability 0.6 What is the loading dose in mg required to reach 0.8mg/ml steady state concentration? A. 20 B. 12 C. 2 D. 0.2

A 5-year-old girl admitted to the Pediatric Intensive Care Unit (PICU) with severe hypotension. The physician prescribed dopamine infusion at a rate of 5mcg/kilogram/minute. The child weights 15 kilograms. How many milliliters are needed from an 80 mg/ml dopamine vial to prepare the 24-hour infusion? A. 1 ml B. 1.4 ml C. 2 ml D. 2.5 ml

A 25-year-old man with leukemia admitted to hematology oncology center. Who is allowed to read the patient file without additional permission? A) Patient's cousin who is working as out-patient nurse in the hospital B) Medical resident in pediatric who wants to explore the risk leukemia C) Clinical nutritionist who is assigned to calculate the requires for the patient D) Pharmacy resident who is planning to do a research cell transplant

Which of the following anti-neoplastic medications is known to cause bone marrow suppression? A. bleomycin B. vincristine C. doxorubicin D. l-asparaginase

Which of the following is an alkylating anticancer agent? A. cyclophosphamide B. fluorouracil C. doxorubicin D. etoposide

42-year-old woman, a mother of 2 boys is diagnosed with cancer, treatment options includes either hysterectomy or chemotherapy The patient refused the surgery because she still wants to daughter, and do not want to receive any chemotherapy in protect her hair and beauty. What will be the most appropriate suggestion for her? A-To starts chemotherapy with very low doses and less frequency B- To go with the option of surgery immediately because it is C-To discuss the risk and benefit with the patient and take the decision D-To force the patient to receive chemotherapy and wear syn hair extensions

Which of the following anti-cancer alkaloids act by stabilizing the microtubule polymer and protecting it from disassembly? A. Paclitaxel B. Colchicine C. Vinblastine D. Camptothesin

Which of the following is a recommendation to reduce the inadvertent intrathecal administration of vincristine? A. dispense the syringe without needle B. dispense vincristine in 60-ml syringe C. dispense vincristine in mini bag instead of syringe D. dispense the vial for the nurse to prepare at the bedside

What is the most common adverse reaction of doxorubicin? A. Bone marrow depression B. Hepatic toxicity C. Cardiac toxicity D. Skin necrosis

What is the therapeutic indication for nilotinib? A. Ulcerative colitis B. Familial hyperlipidemia C. Highly active and relapsing remitting multiple sclerosis D. Philadelphia chromosome positive chronic myelogenous leukemia

40 years old women with breast cancer, topoisomerase is elevated, which drug should be used A- Cyclophosphamide B- Melphalan C- Irinotican D- Methotrexate

Immune system works an important role in cancer treatment by ? A. Macrophage B. cytotoxic C. complex

prevention breast cancer ? A. Vit A 100 B. Vit D 200 C. None of them D. Vit A + vit d

Immune system works an important role in cancer treatment by ? A. Macrophage B. cytotoxic C. complex

Cysteine in chemotherapy agent benefit ? A- Increase Target B- Increase effects C- increase solubility D- More information need

Click image to enlarge Acetaminophen is an antipyretic and an analgesic drug. It binds to a cytosolic protein (see image). Which of the following types of bonds is formed between the protonated amine of the acetaminophen and the cytosolic acid of the aspartate residue of the protein? A. ionic bond B. covalent bond C. hydrogen bond D. VAN_

Which of the following molecules contains double bond? A. CH3 B. CNH C. C2H2 D. C2H4

Quinine is an important antimalarial drug with very complicated structure and is very sensitive stereochemistry (see image). Which pharmacological activity the drug will possess stereochemistry at the arrow has changed from R to S? A. anticancer B. antimalarial C. anticoagulant D. antiarrhythmic IMAGE NUMBER 257.

) Click image to enlarge Acetaminophen is an anti pyretic and an analgesic drug. It binds to a cytosolic protein (see image). Which of the following types of bonds is formed between the protonated amine of the acetaminophen and the carboxylic acid of the aspartate residue of the protein? A) lonic bond B) covalent bond C) hydrogen bond D) van-der walls interaction

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