LT Flashcards
1
Q
Drug can be used as anti-inflammatory with long action.
a) Naproxen
b) Peroxicam
A
b) Peroxicam
2
Q
Summary case with women need analgesic &anti-inflammatory with long action?
a) naproxen
b) Peroxicam
A
b) Peroxicam
3
Q
29 years man take overdose from a drug, then he take antidote, but still no effect. Why?
a) He has tolerance to the antidote.
b) Antidote not work, because it taken after 4hrs.
c) Antidote eliminated too fast from body.
d) Antidote dose was small.
A
d) Antidote dose was small.
4
Q
Biological substance can be stored at
A
2-8 celsius
5
Q
Wrong medication prescribed from doctor, what pharmacist should do?
a) Inform chief pharmacist.
b) Inform prescriber doctor.
c) Inform the patient and tell how badly this drug for him.
d) Inform the health ministry.
A
b) Inform prescriber doctor.
6
Q
After dispensing drug the pharmacist find mistakes, what should do?
a) Refer to prescriber doctor.
b) Head pharmacist.
c) Patient who received the drug.
A
a) Refer to prescriber doctor.
7
Q
Elderly man had hypertension, what should do?
a) Take normal adult dose.
b) Start small initial dose then increase.
c) Start large initial dose then decease.
A
c) Start large initial dose then decease.
8
Q
Young girl has seizure and tremor while using oxycarbamazipine, what should do?
a) Shift to carbamazepine.
b) Shift to clozapine.
c) Shift to topiramate.
d) No change in therapy.
A
c) Shift to topiramate.
9
Q
A middle age man did lab test Fasting blood glucose= 9.1, HbA1c= 9, and he is taking
glipizide, lisinopril, and pioglitazone.
a) Keep on these drugs.
b) Stop glipizideand take metformin.
c) Take insulin.
A
c) Take insulin.
10
Q
Normal range for HBA1C?
a) Non diabetics (4—5.6)
b) High risk (5.7–6.4)
c) Diabetic. (HbA1C equal or above 6.5)
A
a) Non diabetics (4—5.6)
#10 pearsonvue pdf
11
Q
Heparin & warfarin contraindicated with
a) dexamethasone
b) Indomethacin
c) Insulin
A
c) Insulin
**According to the options, if Insulin not present the answer diclofenac
12
Q
Decrease or increase dose by technician to the patient is error?
a) omission error
b) Prescription error
c) Dispensing error
d) Personal error
A
a) omission error
13
Q
Drug with Slow metabolism
a) Phenobarbital
b) Thiopental
c) Pentobarbital
d) Secobarbital
A
a) Phenobarbital
14
Q
Amphotericin B for which infection disease.
a) Subcutaneous
b) Systemic
c) Cutaneous
d) Both A&B
A
d) Both A&B
15
Q
Acyclovir is used for
A
Herpes simplex virus
16
Q
Drug with 500 unit/ml, and total unit needed is 2700 unit, each vial contain 10 ml with conc
100 unit/ml. How many vial will dispense
A
3 vials
17
Q
Metoclopramide MOA –
A
Metoclopramide is principally a dopamine D2 antagonist but also acts as an agonist
on serotonin 5-HT4 receptors and causes weak inhibition of 5-HT3 receptors.
18
Q
Which committee rules out a drug from the hospital
A
Therapeutic evaluation committee.
19
Q
Formula of drug can be adjusted by
A
pharmacy therapeutic committee
20
Q
20.Which drug with statin can increase myopathy?
a) Gemfibrozil
b) gliclazide
c) thyroxin sodium
A
a) Gemfibrozil
DRUGS FOR DYSLIPIDEMIA> FIBRATES/ FIBRIC ACID DERIVATIVES
21
Q
To determine the severity of myopathy caused by statin drugs
A
serum protein kinase.
22
Q
Elderly patient, after he taken statin drug has myopathy. What the analysis or test that he have
to do?
a) lipid profile
b) Muscle thickness
c) Serum creatinine kinase level.
A
c) Serum creatinine kinase level.
23
Q
The treatment of Helicobacter pylori (H. pylori).
a) clarithromycin+pantoprazole
b) clarithromycin+amoxicillin+pantoprazol
A
b) clarithromycin+amoxicillin+pantoprazol
**Omeprazole & metronidazole not in the options.
24
Q
Pt has gastritis due to H pylori, the ttt is -
A
Amoxicillin + Clarithromycin + Omeprazole.
**Sensitivity test of penicillin done after: (range 30 days or more, so will the answers
according to choices.)
25
sensitivity test of penicillin done after:
a) less20 days
b) more than 30 days
c) 25day exactly
d) may be 5day or 3day
b) more than 30 days
26
Penicillin sensitive test is done
a) 10 - 15 days
b) 20 days or less
c) 25 days or more .
c) 25 days or more .
27
Sensitivity test of penicillin done after:
a) 20 days
b) more than 20 days
c) 2 weeks
b) more than 20 days
28
Penicillin sensitivity test for intradermal stage which is must
Skin scratch test
29
Penicillin sensitivity test done??
(Hours)
30
Penicillin allergy skin testing is a relatively simple procedure completed in about
one hour
via scratch and intradermal test in penicillin skin test should wait for (time?). 15-20mint.
31
Female Pt with pneumonia went to the hospital to get vaccine, which should give:
a) Pneumonia + meningitis.
b) Pneumonia + influenza.
c) Pneumonia + meningitis + influenza.
d) Only influenza.
b) Pneumonia + influenza.
32
Patient has lung obstruction and he was not vaccinated, which vaccine should he take?
a) Influenza.
b) Pneumonia and influenza
c) Meningitis and pneumonia.
b) Pneumonia and influenza
33
Rhabdomyolysis can be detected by:
(All answers true)
a) Creatine kinase level.
And can be detected by
b) Serum Ca.
c) Myoglobin K.
d) Urine analysis.
34
Pt. has involuntary movements, while taking antipsychotics, she gain weight, can’t sleep,
isolated from people, which antipsychotics must take:
a) Haloperidol then clozapine
b) fluoxetine then imipramine
c) clozapine then haloperidol
d) imipramine then fluoxetine
c) clozapine then haloperidol
35
If we have sustained release drug, but we break it down into powder instead of using it as
tablet, what will happen?
a) Toxicity will happen. (SR containing multi-dose)
b) Will give same effect.
c) Will give better effect.
d) Pharmacokinetic problems.
a) Toxicity will happen. (SR containing multi-dose)
36
Laxative contraindicated in pregnant is:
a) Ethylene glycol.
b) Castor oil
c) Bisacodyl
d) Glycerin.
b) Castor oil
37
Newborn baby prescribed for him morphine, what is the best route of administration:
a) IV
b) IM
c) SC
d) Suppository.
a) IV
38
Who is the responsible for determining the best dosage form?
a) Prescriber doctor.
b) Pharmacist/Clinical pharmacist.
c) Nursing team.
d) Patient.
b) Pharmacist/Clinical pharmacist.
39
A person is addicted to medications, he entered the hospital suffering from cramps, gave him
diazepam, but there is no effect. So this patient is addicted to any of the following
medications?
a) Cocaine
b) Opioid.
b) Opioid.
40
NICOTINIC DRUGS ARE LABELLED IN HOSPITAL PHARMACY:
a) A
b) I
c) O
d) N
d) N
41
In large amount of parental medication we use
a) Bacteriostatic water
b) Sterile water.
c) Sterile water for injection.
c) Sterile water for injection.
42
In pediatric analgesic for tooth growth pain contraindications and have bad effect in brain.
a) Aspirin
b) acetic acid
c) antiseptic
a) Aspirin
43
Teething gel for children contain
a) Lidocaine
b) aspirin
c) acetic acid
d) antiseptic
d) antiseptic
44
Tooth gels contain one of the following agents.
a) antiseptic
b) antifungal
c) sweeting agent
a) antiseptic
45
Drug must keep in dark box, and used for pain of toothache and can cause more dangerous
effect to infant (seizure and toxicity)
a) Clove oil
b) Ibuprofen susp
c) Lidocaine
d) Viscous gel
a) Clove oil
46
Neonate suffers from cardio coagulopathy, so vit k should be administered through?
a) Iv
b) im
c) supp
d) SC
b) im
47
Man with bmi 85% from his Age so he is?
a) Wt. loss
b) obese
c) highly obese
d) Very obese
d) Very obese
48
Child with bmi 85% from his age so he is
a) weight loss
b) obese
c) highly obese
d) Very obese.
b) obese
49
Child 85% bmi of his age he had muscle and skin thickness test for...
a) edema
b) skin test
c) body fat
d) Vasculation.
c) body fat
50
Five years old child and the weight 80 % of his age, skin thickness and arm muscles are
normal, this child is :
a) Risk for over weight
b) Overweight
c) Under normal.
d) Normal range.
d) Normal range.
there is a BMI percentile and definitional categories childhood weight
51
Antidote for tramadol---
Naloxone
52
Which drug that enhance the minimal alveolar concentration (MAC) of anesthetic?
a) Halothane (Fluothane)
b) Isoflurane (Forane)
c) Enflurane (Ethrane)
d) Desflurane (Suprane)
e) Sevoflurane (Ultane)
f) Nitrous oxide (nitrous oxide)
53
Drugs decrease MAC
Barbiturates, Lidocaine, opioid, and chlorpromazine.
54
Drugs that increase MAC ---
L-dopa, amphetamine, and ephedrine.
55
In elderly, what the physiological effect of drug distribution?
a) decrease water soluble and lipid soluble drug
b) increase both
c) water soluble increase lipid decrease
d) Increase lipid sol. & decrease water sol drugs
d) Increase lipid sol. & decrease water sol drugs
56
Pregnancy woman take naproxen what harm could to baby?
a) uncontrolled bleeding
b) GI reflux disease.
a) uncontrolled bleeding
57
Pregnancy with otitis media?
a) azithromycin
b) cifexime
a. azithromycin
58
Mechanism of action of ciprofloxacin.
a) Cell wall synthesis
b) Inhibit. DNA gyrase
c) Inhibit. MRNA inhibits.
d) Protein synthesis inhibition.
b) Inhibit. DNA gyrase
59
Drug undergo phase 1 metabolism.
a) Diazepam,
b) Lorazepam.
a. Diazepam
60
Effects of benzodiazepine in breastfeeding
no effect
61
disease cause brain and liver damage while using aspirin in children.
a. metabolic syndrome
b. reye disease
b. reye disease
62
the prescription is valid to dispense within:
a. 72 hour
b. 48 hr
c. 24 hr
d. 90 hr
a. 72 hr
63
Maximum days of use of narcotics?
Not more than one day’s medication may be administered at one time. This treatment cannot
last more than three days and may not be renewed or extended.
The nurses should replace the used ampoules from the pharmacy within 3 days from the date
of the prescription.
64
Controlled drug maximum prescription time?
a) 30
b) 45
c) 60
d) 90
d) 90
**If there is no 90 day in choices .the answer will be 30day
65
Uncontrolled drug maximum prescription time?
a) 30 days
b) 45 days
c) 60 days
d) 90 days
a) 30 days
66
Narcotic orders for inpatients:
a) 12hr
b) 24hr
c) 36hr
d) 72hr
b) 24hr
67
Narcotics continuous IV infusion with IV admixture.
a) 1 day
b) 7day
c) 5 days
a) 1 day
68
Non parenteral narcotics can be used for:
a) 15day.
b) 30 day.
c) 45day.
b) 30 day
69
Non parenteral narcotics maximum prescription time ---
30 day.
70
Narcotics indication.
a) Gynecological
b) Obstetrics
c) Analgesic
c) Analgesic
71
Narcotic drugs can be used for:
a) Cancer pain.
b) IBS.
a) Cancer pain.
72
Cocaine over dose can be treated with? No methadone present
a) naloxone
b) opioid agonist
a) naloxone
May be any this Benzodiazepine, dexmedetomidine and rimcazole
** There is no officially approved specific antidote for cocaine overdose.
73
Gasoline fumes induce toxicity of:
a) Lead
b) arsenic
c) lithium
d) magnesium
a) Lead
74
Lead antidote:
--- penicillamine or caEDTA
75
Toxicity of lithium treated by ---
sodium bicarbonate. (Antidote of lithium)
76
.Antiasthmatic used alone, can cause cardiovascular death.
a) Inhaled corticosteroids
b) Inhaled corticosteroids
c) Short acting B agonist
d) Long acting B agonist
c) Short acting B agonist
77
Drug Used for cytomegalovirus
a) abacavir
b) entecavir
c) zanmivir
d) Foscarnet.
d. foscarnet
**If there is no ganciclovir or valganciclovir in choices...... then answer is Foscarnet.
78
77.Imposed oral Narcotics gets addictive after?
a) 15day
b) 20day
c) 30 day
79
65 years old man suffering from heart burn and peptic ulcer. Which drug is not
recommended because of its unwanted effect on central nervous system?
a) Famotidine
b) Cimetidine
c) nizaditine
b) Cimetidine
80
Which drug contraindicated in breastfeeding:
a) Lithium.
b) Warfarin.
c) Methyldopa.
a) Lithium.
81
The best drug for insomnia:
a) Diazepam.
b) Buspirone
c) Zolpidem
c) Zolpidem
82
Which drug suppresses milk production in breastfeeding women?
a) Estrogen.
b) Reserpine.
c) Metoclopramide.
a) Estrogen.
** Estrogen has been shown to decrease the quantity and quality of human milk; use only if
clearly needed; monitor the growth of the infant closely.
83
% of theophylline in aminophylline.
a) 75
b) 85
c) 90
d) 60
b) 85
84
Which drug has anti-androgenic effects?
a) Tamoxifen
b) Mifepristone
c) Finasteride.
d) Anstrazol.
c) Finasteride.
85
Drugs that contraindicated during lactation
a) Anticancer
b) Aspirin
c) Iodine
d) Androgen
e) bromocriptin
a) Anticancer
b) Aspirin
c) Iodine
d) Androgen
e) bromocriptin
**I think Tetracycline is also contraindicated in lactation.
86
Which drug worsens the negative effect of statins on muscles?
a) Gemfibrozil.
b) Cholestyramin.
a) Gemfibrozil.
87
What is best hypnotic for geriatric?
a) Alprazolam.
b) Diazepam.
c) Phenobarbitone.
a) Alprazolam.
* If there is no Zolpidem or zaleplon in the other choices the answer Alprazolam will be
correct.
88
What is the most common dispensed OTC in pharmacy?
a) Oral antiseptic.
b) Analgesic.
c) Antiallergic remedies.
a) Oral antiseptic.
89
Side effect of ciprofloxacin in children:
a) Phototoxcity.
b) Seizures.
c) Vertigo.
a) Phototoxcity.
** If Phototoxcity not in options, choose seizures.
90
Drug has low androgenic activity:
a) Finasteride.
b) flutamide
c) mifepristone
c) mifepristone
*Suppose that the right answer if spironolactone not present is mifepristone.
91
Patient came to the hospital suffering from pain in his leg after playing football. Which
analgesic should be used by injection?
a) Ketorolac.
b) Naproxen.
c) Ibuprofen.
d) Diclofenac.
d) Diclofenac.
**The answer is diclofenac. If there is no Diclofenac in choices, then the answer will be
Ketorolac.
92
Non aqueous preparation.
a) Ear and eye preparation.
b) Syrup and elixir.
c) Essence Colloid and elixir
c) Essence Colloid and elixir
93
Non formulary drugs are dispensed to?
Inpatient (Indoor patients).
** Non-Formulary Drugs shall be clearly documented, on a special Request Form and Direct
Purchase form, and properly labeled and stocked in a separate drawer in the inpatient pharmacy
dispensing area
94
Drug cause sedation for fetus in 3rd trimester?
a) fluoxetine
b) benzodiazepine
c) TCA.
d) antiepileptic drugs
b) benzodiazepine
95
Which drug has more effect as skeletal muscle relaxant?
a) Tubucurarine
b) Doxacurarine.
c) Succinylcholine.
c) Succinylcholine.
96
Pt has Benzodiazepines toxicity, flumazenil is given but patient didn’t respond. Why?
Because antidote was given to patient after 4 hours.
97
Drug waiting to be registered in Saudi drug committee
Non formulary drug
98
Which of the following drug cause nasal bone hypoplasia
--- Warfarin.
99
Drugs to be registered in ministry of health? )بقص َسؤال)
a) Formulary
b) Non formulary
c) Controlled drugs
100
Drug still waiting for approval by therapeutic and pharmacy committee. What do we call
this drug?
a) Formulary drug
b) Non-formulary drug
c) Controlled drug
d) Restricted drug
b) Non-formulary drug
101
All these drugs are controlled drugs EXCEPT
a) Carbamazepine®
b) Rivotril ®
c) Tylenol ®
c) Tylenol ®
102
Which one is OTC drug?
a) Analgesics
b) Warfarin
c) Ciprofloxacin
d) Insulin
a. analgesics
103
Pregnant woman has infection. I don’t remember the m.o. and she is sensitive to penicillin.
And the m.o resistant to erythromycin and clindamycin. Which antibiotic is suitable for her?
a) Ciprofloxacin.
b) Vancomycin.
b) Vancomycin.
104
How many ml syrup u prepare in pharmacy?
a) 15 ml.
b) 30 ml.
c) 45 ml.
d) 60 ml.
d) 60 ml.
105
Which drug is SABA (short acting β2 agonists)?
a) Albuterol.
b) Terbutaline.
c) Salbutamol.
d) Acute therapy.
a. albuterol
106
Target of blood pressure for normal person:
a) 117/70
b) 110/80
c) 140/ 90
b) 110/80
107
20 years girl come to take contraceptive piles which of the following can make oral
contraceptive failed?
a) Rifampicin
b) Amoxicillin
c) Floxacilline
a) Rifampicin
108
n case of Sever state of Alzheimer we use: -
Memantine
109
arget of blood pressure for hypertension patient:
a) 117/70
b) 110/80
c) 140/90
c) 140/90
** If the bold pressure increased to abnormal rang for any reasons in a hypertensive patient, the
goal will be decreasing the blood pressure to 140/90 to protect the patient from organ damage.
110
Role of nicotine in abortion?
By FDA. Cigarette smoking is known to cause: information
a) Spontaneous abortion,
b) Low birth weight
c) Increased perinatal mortality.
d) Potent vasoconstriction... Decrease uterine & placenta blood flow... Risk of
abortion
111
Mechanism of action of memantine treatment Alzheimer:
a) activated muscarinic receptors
b) inhibit choline esterase enzyme
c) Partial activate central nicotinic receptors
d) Decrease enzyme may be this enzyme ( Glutamate NMDA enzymes receptor
antagonist)
d) Decrease enzyme may be this enzyme ( Glutamate NMDA enzymes receptor
antagonist)
** Memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist. The mechanism of
action of memantine is (distinct) from those of the cholinergic agents; it is proposed to be
neuroprotective. Memantine is an uncompetitive antagonist of the N-methyl-D-aspartate
(NMDA) type of glutamate receptors
112
Patient with hemodynamic shock treated with:
a) Saline.
b) Corticosteroid.
a) Saline.
113
Anti-diabetic FDA approved for infants:
Metformin
114
Side effect and adverse drug reaction in geriatrics due to.....
a) Decrease elimination of the drug.
b) Polypharmacy.
c) Geriatric less sensitive to drug effect.
d) Good relation with health providers.
b) Polypharmacy.
115
Mechanical error during filling the prescription:
a) Dispense the wrong drug.
b) Forget to ask about drug allergies.
c) Forget to counsel about drug-drug interaction.
d) Change the drug that no present in prescription.
a) Dispense the wrong drug.
116
Toxicity of TCA imipramine or amitriptyline CNS toxicity can be treated by:
a) Naloxone
b) Alpha agonist
c) Pyridostigmine
b) Alpha agonist
117
Pregnant woman has syphilis can be treated by:
a) ciprofloxacin
b) amoxicillin+clavulanic acid
c) trimethoprim-sulfamethoxazole
b) amoxicillin+clavulanic acid
**If there is no Benzathin penicillin as an option …choose amoxicillin+clavulanic acid.
118
Breast feeding woman need contraceptive which of this:
a) Estrogen.
b) Progesterone.
c) Monophasic pill.
d) Biphasic pills.
b) Progesterone.
** Mono and bi phasic are techniques for administration of combined oral contraceptives
(Estrogen and progesterone).
119
Propranolol similar in action to?
a) Metoprolol
b) Carvedilol
c) pindolol
d) Sotolol
d) Sotolol
120
Breast-feeding woman has hypertension which antihypertensive drug has hazard on baby.
a) Metoprolol
b) Propranolol
c) atenolol
d) verapamil
c) atenolol
121
Barbiturates side effect in elderly patients.
a) ataxia
b) agitation
c) Dementis (agitation).
b. agitation
** If there is no (excitement) choice... another choice if both are not available is (confusion)
122
Drug used in treatment for Hypertension and migraine:
a) clonidine
b) hydralazine
c) minoxidil
d) reserpine
a) clonidine
** If there is no propranolol as an option …choose clonidine.
123
Patient treated from amphetamine addiction; also he has hypertension and depression,
which antihypertensive you give:
a) losartan
b) captopril
c) methyl dopa
d) clonidine
a) losartan
124
Mechanism of action of ramelteon:
a) Melatonin agonist.
b) Melatonin antagonist.
c) Increase Melatonin synthesis.
d) Decrease Melatonin synthesis
a. melatonin agonist
125
Who is the responsible for release of investigational drugs from the manufacturer to the
pharmacy?
a) Chief pharmacist.
b) Physician.
c) Hospital owner.
d) Direct investigator.
a) Chief pharmacist.
126
Mechanism of action of Zolpidem:
a) increase GABA release
b) increase GABA subtype
c) Inhibit GABA release.
b) increase GABA subtype
127
GAD enzyme acting on glutamate produce )بقصت َبراثٍاالخ)
a) Amyl soluble protein
b) Glutamate.
**Glutamate decarboxylase or (GAD) is an enzyme that catalyzes the decarboxylation of
glutamate to GABA and CO2
128
Pregnant woman is allergic to penicillin. Which antibiotic should be given to her as
prophylaxis against streptococci b4 delivery?
a) Penicillin G.
b) Cefazolin.
c) Vancomycin.
d) Clindamycin.
d. clindamycin
129
Drug of choice for nausea and vomiting in pregnant:
a) Domperidone.
b) Cyclizine.
c) Dimenhydrinate.
b. cyclizine
130
Pt adult has vaccinated in 2010 against influenza, 2011 against influenza, 2012 against
meningococcal, 2012 against influenza, 2013 against meningococcal, what is the vaccine
should take now?
a) meningococcal
b) hepatitis
c) influenza
c) influenza
131
Why should finasteride be stopped if woman wants to be pregnant?
a) Cause abortion.
b) Teratogenic effects.
c) Genital malformation to infant.
d) Cranial facial abnormality.
e) Uterine vascular resistance
c) Genital malformation to infant.
132
Which anesthetic cause hepatotoxicity?
a) Ketamine.
b) Nitrous oxide.
c) Isoflurane
d) Propofol.
c) Isoflurane
133
Man got to emergency after burns, toxicity dye to warfarin?
a) Cyanide.
b) Lead.
c) Mercury.
a) Cyanide.
* Interaction between Warfarin and TCA (Tricyclic antidepressant) --- Increase bleeding risk
or increase adverse effect of warfarin (Increase plasma level of warfarin)
134
Why should warfarin be stopped if woman wants to be pregnant?
a) Cause abortion.
b) Teratogenic effects to infant.
c) Genital malformation
d) Cranial facial abnormality.
e) Uterine vascular resistance
b) Teratogenic effects to infant.
135
12 years old taking oxcarbazepine, suffers from rash and redness. What should be done?
a) Lamotrigine.
b) Topiramate.
c) Carbamazepine.
b) Topiramate
**Ethosuximide not in the choices.
136
Pt adult has vaccinated in 2010 against influenza, 2011 against influenza, 2012 against
meningococcal, 2012 against influenza, 2013 against meningococcal, what is the vaccine
should take now?
a) meningococcal
b) hepatitis
c) influenza
c) influenza
137
First baby milk named
colostrum
** colostrum :a yellowish liquid, especially rich in immune factors, secreted by the mammary
gland of female mammals a few days before and after the birth of their young.
138
Pt has lower limb and trunk pain and used antipsychotic drug for 11years, what is his case?
a) acute dystonia
b) tardive dystonia
c) acute dyskinesia
d) tardive dyskinesia
d. tardive dyskinesia
139
Formulating of the drug is done by:
a) Saudi health
b) Drug therapeutic committee.
c) Pharmacist.
b) Drug therapeutic committee.
140
Best Best antidepressants given to an 83 years old
a) Fluoxetine.
b) Alprazolam
a)fluoxetine
141
Lactulose used in hepatic encephalopathy patient to:
a) Acidify the colon to inhibit absorption of ammonia.
b) Alkalization the colon to inhibit absorption of ammonia.
a) Acidify the colon to inhibit absorption of ammonia.
142
Anti-diabetic drug approved by FDA in gestation
Insulin
**Insulin is the drug of choice in gestational diabetes (diabetic pregnant)
** But glargine (long acting insulin) is category C in pregnancy.
** If there is no insulin in choices choose metformin NOT glargine.
143
drug shou;ld be stored in black container to make medical care staff aware and it used for children for pain and it can cause brain injury?
aspirin
144
interactions of CCB with alprazolam:
Only CCB has antidepressant effect.... I think answer will be (CCB increase effect of
antidepressant)
145
Criteria in formulary management system ( information)
a) Safety may be in opition
b) Economy
c) Aesthetic
146
Estrogen receptor positive cause breast cancer which can be treated by
tamoxifen
147
What is the maximum prescription time for narcotic for patient admitted in emergency?
a) 24 hours
b) 72 hours
c) 45 hours
d) 30 hours
a. 24 hours
** 24 hrs. In case of emergency. 3 days (72hr) in case of outpatient.
148
Bisacodyl Mechanism of action?
a) Bulk laxative
b) stimulant laxative
c) stool softener
b) stimulant laxative
149
If a lactating mother has less milk production, what are the effects on nursing infant?
a) constipation
b) loss of appetite
c) diminished weight gain
d) increased sleep
c) diminished weight gain
150
A patient admitted to emergency with cocaine toxicity, what will be the treatment?
a) baclofen
b) naloxone
c) amitriptyline
d) physiostigmine
b) naloxone
151
Iproniazid given to a patient it increases the secretion of nor adrenaline n other amines in
the brain but it’s one adverse effect is it causes hypotension in patient what is the reason..??
a) Increase excretion of nor adrenaline
b) Displacement of nor-adrenaline with dopamine in store.
c) It is highly bound to plasma protein.
d) It’s histaminic effect.
a) Increase excretion of nor adrenalin
152
Iproniazid drug release dopamine, nor adrenaline and other amines but has hypotensive
effect due to
a) It is highly bound to plasma protein.
b) It’s histaminic effect.
c) It increases excretion of nor-adrenaline.
d) Displacement of nor-adrenaline with dopamine in store.
c) It increases excretion of nor-adrenaline.
153
What are the benefits of patient orientation formulary system in hospitals?
a) budget of medicine
b) expensive medicine
c) safe and effective medicines
d) gut relation between the staff n medical officer
c) safe and effective medicines
154
What are the pharmacokinetic parameters studied for a drug before it to the patient and for
estimation of dose in DAT patient?
a) bioequivalence studies
b) gross estimation
a) bioequivalence studies
155
A patient is suffering from insomnia, what should give him:
a) phenobarbital
b) Zolpidem
c) alprazolam
d) Nortriptyline
b) Zolpidem
156
Patient is taking hypnotic Medication, he suffers from irritability and agitation this reaction
related to:
a) Diazepam.
b) Alprazolam
b. Alprazolam
157
Patient stop medication hypnotic he suffered from irritability and Agitation this reaction
related to
Side effect of barbiturates withdrawal symptoms
158
According to Saudi ministry of health, which drug is anti-hyperglycemic?
a) Insulin
b) Metformin
c) Gliclazide
b. Metformin
159
Drug affect fetus in pregnancy cause renal dysfunction?
a) Sulfonyl urea.
b) An angiotensin-converting-enzyme inhibitor (ACE inhibitor)drugs.
b) An angiotensin-converting-enzyme inhibitor (ACE inhibitor)drugs.
160
From OTC Multi-vitamin analogs
vitamin D
161
Levocetirizine can be used after:
a) 6 years
b) 8 years
c) 12 years
d) 16 years.
a. 6 years
162
Levocetirizine used from
a) 5 years old
b) 7 years old
c) 9 years old
d) 12 years old
a. 5 year old
163
Levocetirizine can be used after:
a) over 6 months
b) over 8 years
c) over 12 years
d) Over 16 years.
a. over 6 months
** Levocetirizine: Pediatric drug information:
**Is used in relief of symptoms associated with perennial allergic rhinitis (FDA approved
in ages ≥6 months and adults), seasonal allergic rhinitis (FDA approved in ages ≥2 years
and adults), and treatment of the uncomplicated skin manifestations of chronic idiopathic
urticaria (FDA approved in ages ≥6 months and adults).
Dose in Children 6 months to 5 years – 1.25 mg (1/2 tsp oral solution) once daily in the
evening. ( tsp = tea spoon).
We will choose the youngest age in the choices & if there is 6 months in choices it will
be the answer.
164
Lithium carbonate causes what side effect
decrease creatinine clearance and increase
BUN. (Blood urea nitrogen).
** Results demonstrate that long-term Lithium treatment may cause impairment in renal
concentrating ability, some of which may originate from the effects of Lithium on
vasopressin on hypothalamic level, and a decrease in glomerular filtration rate (GFR). In
the light of these data, we can conclude that long-term administration of Lithium may be a
risk factor for Lithium-induced renal impairment, which is a progressive effect in nature.
165
Physician prescribed warfarin for a woman, but she doesn't tell him that she takes
antidepressant
a) Warfarin increase plasma level
b) Warfarin increase response of antidepressant
c) Warfarin increase metabolism
d) Increase bleeding risk or increase adverse effect of warfarin (Increase
plasma level of warfarin)
d) Increase bleeding risk or increase adverse effect of warfarin (Increase
plasma level of warfarin)
166
Phenothiazine drug has antihistamine effect
promethazine.
167
What is the type of water used in preparation of cold cream?
a) Normal water.
b) Distilled water.
c) Sterile water.
b) Distilled water.
168
When does pharmacist send a report about side effects:
a) Every month
b) Every year.
c) Half annual.
d) 4 times year.
a) Every month
169
If driver has fever and take another road to the city? is due to:
a) loratadin
b) Dipheniramine.
d. Dipheniramine
170
Which drug has less oral bioavailability?
a) ciprofloxacin
b) amoxicillin
c) Imipenem.
d) Vancomycin
d) Vancomycin
**Imipenem used with cilastatin to decrease renal metabolism
171
We give digoxin in case of congestive heart failure for what?
a) Low therapeutic window.
b) Positive inotropic effect.
b. positive inotropic effect
172
How many times will measure drug serum concentration for therapeutic drug monitoring,
in stable patient?
a) Once daily.
b) Once during therapy.
c) Randomly.
b) Once during therapy.
173
Interaction between warfarin and ibuprofen cause increase risk of bleeding, why?
a) Warfarin will be replaced by ibuprofen.
b) Ibuprofen decrease warfarin excretion.
c) Ibuprofen increase warfarin metabolism.
d) Ibuprofen decrease warfarin metabolism
a) Warfarin will be replaced by ibuprofen.
174
Which drug has increasing oral bioavailability when broken from big particle to small
particle?
a) Water soluble.
b) Dissolution rate limited.
c) Absorption rate limited.
b) Dissolution rate limited.
175
Increase osteoporosis in geriatric, will increase:
a) Bone fracture.
b) Urine retention.
a) Bone fracture.
176
27 years pt come to ED with sever HTN & tremors, also he is addicted, and two weeks ago
doctor prescribed to him antidepressant, what is this drug?
a) Amitriptyline TCA.
b) Lorazepam.
c) Trazodone
a) Amitriptyline TCA.
177
What is the parameter used in pharmacokinetics to assess the renal function:
a) Scr.
b) CrCl.
b. CrCl
178
Non formulary drug order reviewed by:
a) Pharmacy & therapeutic committee.
b) Drug & therapeutic committee.
c) Hospital management committee.
d) Ministry of health
a) Pharmacy & therapeutic committee.
179
27 years old Pt has respiratory depression from anesthetic, which drug counteract post
anesthetic respiratory depression.
a) Morphine.
b) Thiopental.
c) Diazepam.
a) Morphine.
180
To be the medical center contains a highly efficient data must be available follows:
a) Cooperation between doctors and pharmacists.
b) To provide stocks of medicines.
c) Choose the appropriate medications and the least side effects.
c) Choose the appropriate medications and the least side effects.
181
Neonate taken sulfonamide suffer from
kernicterus
182
Non formulary drugs given to
Nona fordable Pt
183
The most desired benefit Pt ?
a) Side effects
b) To empty the stock
184
Drug has dopamine receptors blocking on CNS
Metoclopramide
185
Ciprofloxacin indicated for:
a) Fever
b) inhaler Anthrax
c) Tuberculosis
b. inhaler anthrax
186
Pregnancy with renal failure which is contraindicated
ACEI
187
Pregnant women must take which vaccine:
a) Influenza type 2.
b) hepatitis B
c) pneumococcal
a. Influenza type 2
188
Which drug is alkylating?
a) Fluorouracil.
b) Etoposide.
c) Cisplatin.
d) Cyclophosphamide.
d) Cyclophosphamide.
** Alkylating agent: E.g. Cyclophosphamide, chlorambucil, melphalan , busulan, and Cisplatin.
189
Which has drug interaction with antidepressant?
a) Gliclazide
b) Propranolol
c) Sertraline.
c) Sertraline.
190
DRUG decrease dopamine action
a) Segilline
b) Amlodipine.
b) Amlodipine.
191
Case if patient his lab test, BUN -> high, Creatinine -> high, Potassium -> high,
Sodium -> high. Which drug he has to stop from those drugs:
a)Insulin
b)Propanol
c)Gemfibrozil
c)Gemfibrozil
192
Dermatologist wants to prepare drug for Pt with dry skin he consults a pharmacist to
choose proper base, what is your opinion?
a) Ointment base.
b) Cream base.
c) Solution base.
d) Lotion base.
a) Ointment base.
193
Drug will make bioavailability & stomach incompatibility problems, if you break the pill
into half.
a) Enteric coated pills.
b) Uncoated pills.
c) Sugarcoated pills.
d) Film coated pills.
a) Enteric coated pills.
194
Hypnotic Drug in inpatient stays for........ And in outpatient stay for........
195
which drug is toxic for neonate in breastfeeding women:
a) Acyclovir.
b) Metronidazole.
c) Voriconazole.
d) Azithromycin
b) Metronidazole.
d) Azithromycin
the answer metronidazol if it no present the answer will be Voriconazole
he answer metronidazol if it no present the answer will be Voriconazole
196
Which drug can be used for long time treatment asthma in pregnant women:
a) Albuterol.
b) Cromolyn.
c) Theophylline
a) Albuterol.
197
MOA for oral contraceptive:
a) Prevent ovulation.
b) Prevent follicle.
c) Prevent infertility
a) Prevent ovulation.
198
OTC for child with fever:
a) Acetaminophen + ibuprofen.
b) Ibuprofen + diphenhydramine
a) Acetaminophen + ibuprofen.
199
What's the side effect of chloropropamide?
a) Hypoglycemia
b) Cholestic jaundice
c) Hyponatermia
a) Hypoglycemia
b) Cholestic jaundice
c) Hyponatermia
( all answers true)
200
Meaning of trituration:
Meaning of trituration: all this same meaning
(reducing the particle size of a substance)
A purification process of crude chemical compound containing soluble impurities,
Dilution of a potent drug powder with an inert diluent powder usually lactose in a
definite proportion by weight
201
Which has drug interaction with antidepressant?
a) Gliclazide.
b) Propranolol.
c) Sertraline.
c) Sertraline.
202
Patient with muscle pain due to rosovastatin who to monitor this?
a) Its Lipid profile.
b) Creatinine kinase
b) Creatinine kinase
203
The desired patient benefits in formulary system in hospital?
a) Adjust pharmacy budget.
b) Ensure effective &Quality of drug
c) Drug stock
b) Ensure effective &Quality of drug
204
The same question, case of 75 years old have HTN ,DM, hyperglycemia what his score
according to CHADS
a) 1
b) 2
c) 3
d) 4
d) 4
Age 2 HTN 1 DM 1.
205
Pregnant women with osteoarthritis, which is the last choice?
a) acetaminophen
b) glucosamine
c) Aspirin
b) glucosamine
206
To be the medical center contains a highly efficient data must be available follows:
a) Cooperation between doctors and pharmacists.
b) To provide stocks of medicines.
c) Choose the appropriate medications and the least side effects
c) Choose the appropriate medications and the least side effects
207
Parental anesthesia commonly used for?
a) Rapid onset of Action.
b) Maintain anesthetic effects for long time
c) Increase MAC for others.
d) Less respiratory collapse & incidence of death
a) Rapid onset of Action.
208
When choosing a drug according to
a) appearance
b) expensive cost
c) efficacy
d) Safety.
d) Safety.
209
In obese patient drug distribution, the lipid soluble drug will?
a) Increase.
b) Decrease
c) Unchanged.
d) Initially increase and suddenly decrease
a) Increase.
210
drug used for HIV because it prevents viral RNA
a) Didanoside.
b) Amantadine.
c) Voriconazole
a) Didanoside.
211
How many grams in one bound?
1000 gram ----- 2.2 bound
X------- 1
x= 454.5 gram
212
The daily dose of prednisolone is 100 mg four times daily; pharmacist issued 2 bottles of
125 ml to patient containing 8mg/ ml.
How many days these two bottles provide the daily dos?
a) 4 day
b) 5 day
c) 3 day
d) 2 day
b. 5 day
**He needs 100 mg 4 time daily .so 400 mg per day . 8mg found in 1 ml so 400mg found in 50ml
.pharmacist have 2 bottles 125 ml .so we have 250 ml. We need 50 ml per day .so it's enough 5
days
213
Allopurinol dose in Pt with CrCl = 3 gml/min is:
a) 100 mg/day.
b) 150.
c) 200.
d) 250.
a) 100 mg/day.
CrCl 10-20 mL/min: 200 mg/daily.
** CrCl 3-9 mL/min: 100 mg/daily
214
Adult dose 250 mg what dose of. child his body s surfacr area (BSA).7cm2.?
average adullt BSA =173 cm2
173______250
70_____x
X= 70*250/173=101
215
What the clearance value that eliminated by non-renal.
Renal clearance value 4.75 l/hr. 65%eliminates by renal.
65/100 * y = 4.75
Y = 475/65 = 7.3 (clearance value)
non renal clearance= 7.3-4.75 = 2.255
216
Drug 30%w/v prepared from Drug 60%w/v in stock from if the drug was 300ml what’s the
volume in stock drug?
30---------1000ml
x----------300ml
x=30*300/100=90mg
60mg--------100
90mg-------x
X=9000/60=150ml
217
Drug is 125ml/5ml and patient takes 4mg/day what's the weight of patient
218
Young girl wt30kg dose 20mg daily/kg...how may days for 25mg?
30*20=600mg/daily
600----------1 day
25mg-------x
x=600/25 =24 days this present in option
