Chapter 47: Colon and Rectum- Polyposis Syndromes (FAP) Flashcards
1
Q
What is another name for this condition?
A
Familial Polyposis
2
Q
What are the characteristics?
A
- Hundreds of adenomatous polyps within the rectum and colon that begin developing at puberty
- all undiagnosed, untreated patients develop cancer by ages 40 to 50
3
Q
What is the inheritance pattern?
A
Autosomal dominant (i.e., 50% of offspring)
4
Q
What is the genetic defect?
A
Adenomatous Polyposis Coli (APC) gene
5
Q
What is the treatment?
A
Total proctocolectomy and ileostomy
Total colectomy and rectal mucosal removal (mucosal proctectomy) and ileoanal anastomosis
6
Q
With FAP, what other tumor must be looked for?
A
Duodenal tumors
