Intracranial Neoplasia

Question 1

Rossmeisl Jr, JAVMA, 2013:
Palliatively treated primary brain tumors

1. MST?
2. Were shorter survival times achieved for infratentorial (cerebellum, pons, medulla) or supratentorial (cerebrum) tumors?

Answer 1

Rossmeisl Jr, JAVMA, 2013:

1. MST: 69 days
2. Infratentorial tumors were associated with shorter survival times than supratentorial tumors

Question 2

Marino, Vet Surg, 2014:

Adverse effects of CUSA-associated diencephalic mass removal?

Answer 2

Marino, Vet Surg, 2014:

Hyperthermia and hypernatremia

Question 3

Ishikawa, JAVMA, 2016:

1. MRI characteristics of meningiomas vs intracranial histiocytic sarcomas?
2. Displacement of vessels by meningiomas vs intracranial histiocytic sarcomas?

Answer 3

Ishikawa, JAVMA, 2016:

1. Most meningiomas were hyperintense on T2W and FLAIR MRI images, and most intracranial histiocytic sarcomas were isointense or hypointense on T2W and FLAIR MRI images
2. Vessels adjacent to meningiomas were displaced in 89% of the dogs, whereas vessels adjacent to intracranial histiocytic sarcomas were not displaced

Question 4

Kohler, JAVMA, 2018:
Cytoreductive surgery for suspected primary intracranial masses

1. Mortality rate?
2. Major complication rate?
3. What factors were associated with development of major complications or death?
4. What % were non-tumorous lesions?
5. What factor was associated with the lowest survival rate?

Answer 4

Kohler, JAVMA, 2018:

1. 13% mortality rate
2. 19% major complication rate
3. Abnormal findings on pre-op neuro exam, dogs undergoing a suboccipital approach
4. 8% were non-tumorous lesions
5. Dogs that developed aspiration pneumonia had the lowest survival rate

Question 5

Forward, Vet Surg, 2018:

1. Post-op complication rate following intracranial surgery?
2. Most common post-op complication?

Answer 5

Forward, Vet Surg, 2018:

1. 47% post-op complication rate
2. Aspiration pneumonia was the most common post-op complication

Question 6

Nakano, Vet Surg, 2018:

Agreement between intensities and pattern of pre-op gadolinium enhancement on MRI and intra-op fluorescein sodium staining?

Answer 6

Nakano, Vet Surg, 2018:

Intensities and pattern of pre-op gadolinium enhancement on MRI agreed with intra-op fluorescein staining

Question 7

Kani, JVIM, 2019:

1. % agreement between stereotactic brain biopsy and surgical/necropsy specimens?
2. Diagnostic accuracy of stereotactic brain biopsy?
3. Diagnostic concordance for meningiomas vs gliomas?

Answer 7

Kani, JVIM, 2019:

1. 97% agreement between stereotactic brain biopsy and surgical/necropsy specimens
2. 81% diagnostic accuracy
3. Meningiomas: perfect agreement
   Gliomas: 78% agreement