DM (Exam #3) Flashcards
Is GLUT4 insulin-dependent or insulin-independent?
Insulin-dependent
Treatment for hypoglycemia?
Glucose (IV) = fastest
What two insulin types can be given IV?
BOLUS
- Rapid-Acting Insulin
- Short-Acting Insulin
What type of Insulin is used in insulin pumps?
Rapid-Acting Insulin
What type of Insulin is used first in Type II DM? When would this be considered?
Long-Acting Insulin
- Used if A1c is 10+% + Metformin
Is Rapid-Acting Insulin or Short-Acting Insulin preferred, and why?
Rapid-Acting Insulin preferred due to less hypoglycemia
- Less “tail-end”
What four factors must be considered when picking a Type II DM drug?
- ASCVD
- CKD
- Weight
- Hypoglycemia risk
Which medication decreases ALL-cause mortality events?
Metformin
What class of drugs have the name hint “-tide”?
GLP-1 Receptor Agonists
What class of drugs have the name hint “-gliptin”?
DPP-4 Inhibitors
What class of drugs have the name hint “-gliflozin”?
SGLT-2 Inhibitors
What class of drugs have the name hint “-glitazone”?
TZDs
Which GLP-1 Receptor Agonists is the only ORAL form?
Semaglutide
What is an important PK associated with DPP-4 Inhibitors?
ORAL administration
What medication can be used as an alternative to SUs, and why?
Repaglinide
- Similar to SUs but NO sulfa allergy risk
