9 Flashcards

(39 cards)

1
Q

what are the risks of low BP

A

hypotension, inability to exercise, fatigue

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2
Q

what are the risks of high BP

A

aneurysms causing a hemorrgahic stroke

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3
Q

which arteries are particurlary at risk in physical stress of hypertension

A

atheromatous arteries bc theyre less compliant. so high bp can cause atheroma to rupture then become a thrombus or embolus and block arteries

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4
Q

what are the two systems that regulate BP and hoe fast do they act

A
neuronal system (fast acting)
hormonal system (slow acting)
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5
Q

what’s the name of the hormonal system that regulates BP

A

renin angiotensin aldosterone hormonal system

RAA RAA RASPUTIN

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6
Q

what type of feedback is the neuronal control of BP

where’s the sensor?

A

negative feedback
sensor is found in carotid sinus in the internal carotid arterty
other sensor is in aortic sinus above aortic valve

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7
Q

what’s one key feature of artery walls in the sinus

A

they have more elastic fibres and so are more stretchy. they distend during each systole

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8
Q

what nerve endings are found in the carotid sinus and what are they sensitive to

A

sinus nerve endings which are sensitive to the stretch in the sinus wall.

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9
Q

what two nerves may the sinus nerve join after it gets excited

A

glossopharyngeal (9) or vagus cranial nerve. (10)

or both!!!!!!

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10
Q

what does carotid body sense

A

sensor for blood chemistry! like 02 blood levels

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11
Q

what cranial nerve does the glossopharyngeal nerve originate from

A

9 cranial

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12
Q

what type of cranial nerve is the glossopharyngeal nerve

A

mixed nerve.
PRIMARILY sensory (from carotid sinus, tongue, pharynx, larynx
motor (secretomotor. parasympathetic to parotid gland and stylopharyngues)

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13
Q

what type of cranial nerve is the vagus nerve

A

mixed nerve.
sensory (from lungs, heart, oesophagus)
motor (lungs heart oesophagus=

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14
Q

where do afferent nerve (vagus and glossopharyngeal) synapse

A

on nucleus of the solitary tract (NTS) of medulla oblongata

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15
Q

where is the nucleus of the solitary tract in relation

A

rostrocaudally within lower medulla

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16
Q

what’s the integrating centre for visceral afferents from mouth, throat and neck

A

the nucleus of the solitary tract

17
Q

what does the nucleus of the solitary tract project to

A

vasomotor centre.

18
Q

where is the vasomotor centre located

A

rostral ventrolateral of the medulla

19
Q

what is the function of the vasomotor centre

A

to go, ok does the info from the sinus match the normal blood BP

20
Q

how does the vasomotor centre correct an inadequate BP

A

through SNS and PNS

SNS via reticulospinal tract

PNS via nucleus ambiguous

21
Q

what receptors sense the changes to carotid sinus wall

22
Q

where are baroreceptors located

A

in carotid sinus

23
Q

what is the response of baroreceptors

24
Q

which of high or low BP corresponds to high baroreceptor input and what’s the result

A

high BP

activation of parasympathetic

25
which of high or low BP corresponds to low baroreceptor input and what's the result
low BP | activation of sympathetic and INHIBITION of parasympathetic
26
what is the equation for mean arterial output
MAP= CO x total peripheral resistance
27
where do reticulospinal tract axons synapse
on sympathetic pre-ganglionic neurons in the intermediate part (IML) of the lumbar and thoracic ventral horn.
28
where do lateral reticulospinal tract axons arise from
From the reticular formation of the medulla of the brainstem.
29
what hormone do postganglionic neurones release to act on arteriole smooth muscle
noradrenaline on alpha1 adrenergic receptors
30
when the baron¡receptor input is too high what happens
vasomotor centre is inhibited so sympathetic system is shut off parasympathetic is activated via nucleus ambiguous which stimulates vagus nerve which acts on SA node to slow HR and CO.
31
which of SNS and PNS affects resistance to reduce BP
sympathetic results in vasoconstriction | para only reduces HR
32
what's the baroreceptor reflex
the observation that electrical stimulation of baroreceptors reduces BP. ​
33
what's a carotid massage
medical maneuver that can be used to reduce BP or slow down a dangerously rapid heartbeat or to diagnose certain heart rhythm disturbances. Massaging the sinus in this way increases the rate of firing in the sinus nerve and increases vagal output. To perform a carotid massage, you’ll need to massage the area at the base of the patient’s neck, where the carotid artery enters the head. An incorrectly performed CSM can cause serious health repercussions, especially in elderly patients and should only be used by experienced health professionals (see URL below) ​
34
what's essential or type 1 hyper T
where there is no clear pathology associated with the condition.
35
what's one theory underlying hyperT
feedback signal has decreased because the receptors in the carotid sinus have come less sensitive to stretch
36
why would the baroreceptors in carotid sinus be less sensitive
bc the walls of the sinus are less elastic than normal so it will require greater pressure to stretch them the normal amount.
37
why do smokers tend to be hypertensive
Cigarette smoking produces free radicals in the blood that damage the arterial endothelium and elastic lamina, resulting in arterial stiffness, inflammation, and alterations to release of relaxing and anti-thrombotic factors. ​ ​ If this damage extends to the carotid sinus, this could explain why smokers tend to be hypertensive. maybe be permanent
38
what conditions are associated with hyperT and why
diabetes I or II bc damages endothelium | type A ppl pron e to chronic stress
39
lifestyle change to fix BP
exercise