9 - Radiation Flashcards

(59 cards)

1
Q

Gray

A

Absorption of on ejoule of radiation energy per one kilogram of matter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Vast majority of tumors treated with radiation will die due to

A

Necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The four R

A

Repair, repopulation, redistribution, reoxygenating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which tumor can u see response rlly quickly

A

Lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The most important R

A

Repair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Repair can happen in both

A

Tumor and normal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What % of normal cells are recovered due to compensatory proliferation

A

50 - 60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Redistribution has to do with

A

Cell cycles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What cell phase is cell most sensitive to radiation

A

G2/M

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What two blocks of cell cycle

A

G1 S and G2 M

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What % of tumors have hypoxia

A

50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Oxygenated cells are more sensitive to

A

Radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acute hypoxia

A

Reopening of closed capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Chronic hypoxia

A

Oxygenated cells die allowing oxygen to diffuse to new areas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Definitive radiation

A

Long term tumor control, daily treatments, small daily dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Palliative radiation

A

Shorter survival times, weekly treatments, high daily dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Acute side effects of radiation related to

A

Stem cell damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Acute side effects starts

A

During the third week of treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Acute side effects last

A

2 -3 weeks after treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Acute Sid effects are related to

A

Total dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Special acute effects

A

Tear glands, lung tissue, brain tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Topical treatment to acute side effects

A

Clean radiation site, ointments, vitamin E oil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Oral treatment for acute side effects

A

NSAID , Gabapentin, tramadol, opioids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Ointments used for acute side effects

A

Proteque and silvadene

25
Late side effects of radiation are related to
Fraction size
26
Late effects of radiation
Necrosis, fibrosis and secondary tumor
27
Late side effects are known as
Stochastic events - random, months to years later
28
Latest radiotherapy
Stereotactic radiotherpahhy
29
SRS
Stereotactic radio surgery
30
SRS was made for
Neuro tissue
31
SRBT made for
Multiple fractions, tissue besides neuro
32
Stereotactic radiotherapy can delivered what doses
10 - 20
33
How many beans angle for SRS
5 to 9
34
Each beam can have how many beamlets SRS
100
35
Normal tissues receives what dose in SRS
Minimal
36
Tumor area receives what doses with SRS
High
37
Gammaknife is what source
Cobalt
38
Benefit of stereotactic radiotherapy
Less acute side effects, shorter course of radiation , less anesthesia
39
Pitfalls fo SRS
Not all rumors can be treated, must have target, scar lines cannot be treated
40
Late side effects of pituitary tumors
Blindness 8 - 12 months post treatment
41
Best to treat pituitary treatment with
Congenital fractionated protocols
42
43
Mast cell tumor have what chance of cure
95
44
Brain tumors have what response rate
95
45
Median survival time brain tumor
12 months
46
Thyroid definitive median survival time
4 years
47
Thyroid median survival time palliative
2
48
Anal sac carcinomas definitive time
18 - 24 months
49
Anal sac carcinomas palliative
12 - 18 months
50
Nasal carcinoma.sarcoma response rate
95 - 98
51
Definitive nasal carcinoma
12 - 18 months
52
Palliative nasal carcinoma
6 - 8 months
53
Nasal lymphoma definitive
18 - 24 months
54
Nasal lymphoma palliative
2 - 12 months
55
Oral malignant melanoma response rate 90
Oral squamous cell carcinoma definitive
56
Oral squamous cell carcinoma Definitiev
18 - 25
57
Palliative oral sq cell carcinoma dogs
12 months
58
Oral sq cell carcinoma cats palliative
1/3 do not response
59