feb 21 2021

Question 1

presentation of kawasaki disease

Answer 1

• conjunctivitis
• mucositis
• cervical lymphadenopathy
• rash
• erythyma and edema of hands/feet
• periungal desquamation

Question 2

what area is periungal?

Answer 2

near the nails

Question 3

treatment of kawasaki disease?

Answer 3

IV immunoglobulin and aspirin

Question 4

what is the most common cause of AA amyloidosis in the USA?

Answer 4

rheumatoid arthritis

Question 5

senile purpura is most common in whcih population?

Answer 5

the elderly

Question 6

findings in senile purpura?

Answer 6

echymosis, skin fragility and normal coag findings

Question 7

path behind senile purpura?

Answer 7

loss of elastic fibers in perivascular connective tissue

Question 8

next step in clinical diagnosis of breath holding spells?

Answer 8

check for iron deficient anemia which can contribute

Question 9

treatment of breath holding spells?

Answer 9

treat anemia if present, if no anemia then nothing

Question 10

what is blepharitis?

Answer 10

disorder caused by inflammation of the eyelid margins

Question 11

blepharitis presentation

Answer 11

burning or itching of eyelids, discharge (crusting in morning), foreign body sensation in eye

Question 12

treatment of blepharitis

Answer 12

supportive - warm compress, lid massage, gentle scrubs

Question 13

MOA of tacrolimus

Answer 13

calcineurin inhibitor

Question 14

main side effects of calcineuron inhibits?

Answer 14

• hypertension
• neurotoxicity
• nephrotoxicity
• glucose intolerence

Question 15

which adverse effects may be seen in the heart for patients on digoxin?

Answer 15

• atrial tachycardia

- AV block

Question 16

what is the most common bug behind febrile neutropenia?

Answer 16

pseudomonas

Question 17

how to treat febrile neutropenia ?

Answer 17

antibiotic with pseudomonas coverage (such as piperacillin-tazobactam)

Question 18

what is hemoglobin H disease?

Answer 18

when 3 alpha genes are lost, and hemoglobin H forms which is tetramers of nonalpha chains (beta or gamma)

Question 19

in adults, what is hemoglobin H made of?

Answer 19

beta tetramers

Question 20

in fetuses and infants, what is hemoglobin H made of?

Answer 20

gamma tetramers

Question 21

what is the MCV in alpha thalasemia?

Answer 21

low

Question 22

what is the erythocyte count in alpha thalasemia?

Answer 22

high

Question 23

what kind of cell will be seen on peripheral smear in alpha thalasemia?

Answer 23

target cells

Question 24

clinical manifestations of chikungunya fever?

Answer 24

• fever
• rash
• malaise
• lymphadenopathy
• polyarthralgias
• lymphopenia and thrombocytopenia

Question 25

renal complication of systemic sclerosis?

Answer 25

scleroderma renal crisis

Question 26

path of scleroderma renal crisis?

Answer 26

raynauds vascular injury leads to renal ischemia, resulting in activation of the RAS -> increase in blood pressure -> cycle of renal damage and worsening blood pressure

Question 27

how do you treat scleroderma renal crisis?

Answer 27

ACE inhibitiors - disrupt the RAS

Question 28

what substance in a blood transfusion can chelate calcium?

Answer 28

citrate

Question 29

what is a risk factor for MALT?

Answer 29

H pylori