Glomerular Disease

Question 1

glomerulus

Answer 1

capillary network that sits in Bowman’s Capsule

Question 2

2 processes of glomerulus

Answer 2

ultrafiltration & reabsorption

Question 3

alteration in permeability of glomerulus causes what

Answer 3

more or less components filtered out of blood and into urine (fluids, electrolytes, proteins, glucose, etc.)

Question 4

inc permb = more or less components filtered out

Answer 4

MORE filtered out (inc urine output)

Question 5

5 categories of glomerular disease

Answer 5

1) acute nephritic syndromes
2) nephrotic syndromes
3) asymptomatic proteinuria & hematuria
4) acute glomerulonephritis
5) chronic glomerulonephritis

Question 6

acute nephritic syndromes

Answer 6

• Dec glomerular permb (inc GFR) –> retain fluids (water & electrolytes) & nitrogenous wastes
• Very serious cmplx (azotemia, HTN, edema)

Question 7

nephrotic syndromes

Answer 7

• Inc glomerular permb (inc GFR) –> lose components in urine that should not be excreted
• Proteinuria, hypoalbuminemia
• Hyperlipidemia

Question 8

why does hyperlipidemia occur in nephrotic syndromes (2)

Answer 8

r/t liver responding to hypoalbuminemia by producing more proteins & LDLs –> lipiduria

Question 9

asymptomatic proteinuria & hematuria

Answer 9

• Asympt in terms of obvious renal damage –> no impairment of kidney Fx (normal GFR)
• Less proteinuria than nephrotic syndromes (less severe)