A01 biological therapies for schizophrenia Flashcards
What are the 2 biological therapies
Anti psychotic medication Electroconvulsive therapy (ect)
What are the 2 sections of anti psychotic medication
Conventional psychotic drugs
Atypical psychotic drugs
What are anti psychotic drygs
Drugs used ti treat severe psychotic illnesses
Schizo
Bipolar disorder
Which of the 2 types of drugs combats which symptoms?
Conventional drugs = positive
Atypical drugs = positive and thought to combat negative
Hiw do conventional an it psychotics work
5
Reduce effects of dopamine
So reduce symptoms of schizo
They’re dopamine antagonists
Bind to D2 (dopamine) receptors but don’t stimulate them and block their action
Due to reduced dopamine system stimulation they reduce positive symptoms of schizo eg hallucinations and delusions
How do atypical anti psychotic drugs work
Like conventual drugs
But thought to block serotonin receptors too
Who studied atypical psychotic drugs
Rimington and kapur
What did remington and kapur find
Atypical anti psychotic drugs worked by blocking D2 receptors
But they blocked them for a short time - they dissociate quickly compared to conventional onez
Why do atypical drugs have lower leveks of side effects
They dissociate quickly from the D2 receptors compared to conventional
What are the 2 section of electroconvulsive therapy
Historical origins
What happens in ect
Who tested effectiveness of ect
Karagulla
What did karagulla find
Recovery from schizo after ect lower than control group
Conclusion from historical origins of ect
Ect isn’t a god therapy for schizo
Can be harmful
What happens in ect
4 steps
Patient first made unconscious
Patient is injected with a nerve blocking agent to prevent them from contracting during procedure which could lead to bone fractures
A small amount of electrical current passed through the brain lasting half a second
This produces a seizure lasting up to one minute and affects entire brain
How could you improve ect
Combining it with anti psychotic medication reduces symptoms of schizo
