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Flashcards in Acute kidney injury Deck (17):
1

post renal AKI =

impaired effective renal perfusion

1

post renal  aki =

obstruction of urinary flow

1

differentiate volume depletion vs ATN proximal tubular injury

FEna < 1% = volume depletion

FENa > 2% = ATN

2

rule out post-renal aki via

renal imaging

4

oliguria = 

urine 400-500ml/day

4

in prerenal aki

decreased perfusion > ___ > increased reabsorption of Na at ____ > appropriate oliguria

decreased perfusion > increased AngII and ADH > increased abs of Na at proximal tubule appropriate oliguria

5

azotemia = 

elevated nitrogen waste products related to insufficient blood filtering

6

hydronehprosis in post-renal AKI

distention and dilation of renal pelvis calyces

7

nitrogenous waste product of protein metabolism, less reliable than creatinine due to variation in protein intake, catablolic rate and tubular reabsorption

BUN

9

AKI dianositc criteria

48 hours

increase in serum creatinine of 0.3mg/dl OR

50% increase in creatinine OR

reudction of urine <500ml in 24 hours

10

renal aki = 

intrinsic renal disease (glomerular, tubular, interstitial, vascular)

11

uremia =

kidney failure > toxic effects of high nitrogenous substances in blood

12

FENa% = 

Una (PCr)

______

PNa(UCr)

13

granular casts (muddy brown urine) seen in cases of

acute tubular necrosis

15

morphologic features ATN

tubular dilation

attenuation of tubular epithelium

loss of epithelial brush border

granular casts

mitotic figures (regenerative change)

16

process of coordinated tubule regeneration in ATN

epithelial de-differentiation > proliferation > migration > restablishing cell polarity

(no direct repopulation)

17

in prerenal AKI, increasesd reabsorption of urea > 

elevation of BUN out of proportion to creatinine (20:1)