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Renal/Resp > Resp Viruses > Flashcards

Resp Viruses Flashcards

(52 cards)

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1
Q

responsible for summer “cold and flu” resp infections and undifferentiated fevers

A

enteroviruses

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1
Q

___ complications of parainfluenza virus infections common in young,

may progess to ___

A

lower respiratory conplications

Croup

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2
Q

basic clinical features influenza

A

self-limited 3-7 days

secondary bacterial infections cause of death:

strep pneumo

staph a.

haemophilus influenzae

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2
Q

subacure scleorising panencephalits in measels infection

A

CNS - personality

behavior

memory changes

myclonic jerks

spasticity

blindness

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3
Q

(drugs)inhibit uncoating by blocking M2 proteins

A

amantadine

rimantidine

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4
Q

temperature sensitivity rhinovirus

A

grows better at 33 than 37

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4
Q

pharyngocojunctival fever in adenovirus infection

A

red eyes

sore throat

febrile

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5
Q

vaccine adenovirus

A

not for public (type 4 and 7 in works)

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5
Q

virus morphology picorna

A

+RNA non-enveloped

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7
Q

pathogenesis influenza

A

infects ciliated epithial cells

replication destroys resp epithelium

cytotoxic T cell - mediated damage

(viremia does NOT play a major role)

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7
Q

vaccine respiratory syncytial virus

A

natural infection does not prevent re-infection

re-infection especially risky in elderly

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7
Q

emerging resp viruses isolated to bats > pigs > humans in australia and Asia

A

hendra virus

nipah virus

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9
Q

dates and transmission H5N1

A

2003-Junly 2014

does not transmit easily among people

household poultry or contaminated environment

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10
Q

adenovirus disease sequale

A

acute resp disease

pneumonia

pharyngoconjunctival fever

conjunctivitis

GI

hemorrhagic cystitis (bladder inflam)

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11
Q

treatment for respiratory syncytial virus

healthy infant

premature/immunocompromised infant

premature infants

A

healthy - supportive O2, fluids, nebulized cold steam

**premature or immunocomp: **aerosolized ribavirin

**premature infants: **passive immunisation with anti-RSV Ig and humanized monoclonal abx

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11
Q

vaccines metapneumovirus

A

none (or therapies)

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12
Q

virus morphology orthomyxo and paramyxo viruses

A

-RNA,

enveloped

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13
Q

influenza A, B C, virus morphology and family

A

orthomyxoviridae

segmented -RNA

enveloped

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14
Q

atypical measels presentatoin

A

intense rash

vesicles, petechiae, prupura, or urticaria

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15
Q

vaccines Rhinovirus

A

none

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16
Q

antibodies against future influenza infections are specific for

Study These Flashcards
A

epitopes on hemagglutinin

neuraminidase proteins

17
Q

most common cause of death in children with measles

19
Q

symptomology MERS-CoV

Study These Flashcards
A

severe pneumonia and renal failure

still birth

nosocomial infections possible

19
Q

post measles encepahlitis

Study These Flashcards
A

headache

confusion

vomitng

coma after rashi disapates

20
metapneumovirus vs RSV
RSV milder, severe disease only in infants, elderly, immunocompromised
21
parainfluena virus serotypes most likely to cause Croup
Type 1 an d 2
21
infects everyone by age 2
respiratoy syncytial virus
22
metapneumovirus ID'd via
RT-PCR
23
virus morphology corona virus
+RNA enveloped
25
vaccine Coronavirus SARS
none
26
influenza (drugs) inhibit release of progeny influenza virus (neuraminidase inhibitors)
Zanamivir Oseltamivir
27
SARS viral class
coronavirus
28
influenza ___ only undergoes minor antigenic changes (drift)
B
30
rare complications of influenza
myositis and cardiac involvement guillain Barre encephalitis reye syndrome
31
symptoms EV-D68 enterovirus
severe resp infection wheezing (higher risk in asthatmatic) difficulty breathing (otherwise ill-defined)
32
coronaviruses limited to
upper RT (invects epithelial cells)
34
infection time for parainfluenza viruses
fall and winter
34
disease states parainfleunza viruses type 1-4
type 1 Croup type 2 Croup type 3 bronchiolitis in small infants type 4 - mild disease
35
location in RT MERS-CoV
lower resp tract (victims with higher viral loads)
36
clinical consequences of respiratory syncytial viral infection Children \< 1 Children Adults+older children
bronchitis, pneumoia, fever cough dypsnea and cyanosis **children: **febriel rhinitis and pharngitis **adults+older children: ** common cold
38
ideal temperature coronaviruses
33-35
39
disease state resp syncytial virus
**localized RT infection - no systmemic sprea** **airway blockage in infants** virused induced CPE includes syncitia (giant cells,) induction of cytonkines
40
respiratory syncytial virus mechanism of airway blockade in infants,
virus induced CPE includes syncitia (multinucleated giant cells) induction of inflammtory cytokines
41
transmission route SARS coronavirus source
face-to-face source: bats, asian animal markets
43
Rhinovirus ___ resistant to uncoating prevention drug mechanisms
rhinovirus C
44
diseases caused by coronaviruses
common colds
45
dates and transmission H7N9 october 2 2014
does not transmit easily among people
47
all children infected by age 5
metapneumovirus
49
vaccine for parainfluenza viruses
none
50
clincical conseuquneces of measels infections
**c**ough **c**onjunctivitis **c**oryza **c**omplications - otitis media, croup, penumonia (maculopapular rash, photophobia, koplic spots)
51
treatment for severe adenovirus infections in immunocompromised
cidofovir
52
infects humans, bats, camels does not transfer person-to-person readily
MERS-CoV

Renal/Resp (43 decks)

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