Alim 2: Pancreas

Question 1

Which kind of pancreatitis do cats get?

Answer 1

Chronic

Question 2

Which enzymes interact at low pH in pancreatitis?

Answer 2

Trypsinogen and lysosomal enzymes

Question 3

What is released in the pancreas which interacts with other enzymes and causes inflammation, oedema and haemorrhage and necrosis?

Answer 3

Trypsin

Question 4

Pancreatitis signs in dogs?

Answer 4

Anorexia, vomiting, epigastric pain, diarrhoea, dehydration

Question 5

Pancreatitis signs in cats?

Answer 5

Inappetance, anorexia, listlessness, weight loss, dehydration

Question 6

What % of pancreatitis does ultrasound show?

Answer 6

60%

Question 7

CBC signs in dogs with pancreatitis?

Answer 7

Neutrophilia with left shift, anaemia, haemoconcentration from dehydration, thrombocytopaenia

Question 8

CBC signs in cats with pancreatitis?

Answer 8

Mild anaemia or haemoconcentration

Question 9

Biochemistry changes in dogs with pancreatitis?

Answer 9

Electrolyte changes from vomiting, azotaemia, high urine SG, raised liver enzymes, low albumin, low Ca, high cholesterol

Question 10

Biochemistry changes in cats with pancreatitis?

Answer 10

Azotaemia, high urine SG, raised liver enzymes, increased bilirubin, low Ca

Question 11

What are two pancreas-specific tests?

Answer 11

Amylase and lipase

Question 12

In dogs, how much are amylase and lipase raised in pancreatitis?

Answer 12

4x

Question 13

Why don’t amylase and lipase increase in cats?

Answer 13

Usually chronic

Question 14

Why do you see amylase and lipase increase in renal disease?

Answer 14

Cleared by kidney

Question 15

What is cut-off like for pancreatitis if also have renal disease?

Answer 15

Higher

Question 16

How do steroids affect lipase and amylase?

Answer 16

Increase lipase, reduce amylase

Question 17

How does phenobarb affect amylase and lipase?

Answer 17

Increases both

Question 18

What other conditions increase both amylase and lipase?

Answer 18

Liver disease, tumours, amyloidosis, IBD

Question 19

What is the only use for the presence of TAP in urine in pancreatitis?

Answer 19

Research

Question 20

How long does the TAP urine test work for?

Answer 20

48 hours

Question 21

What is TLI used to idnetify?

Answer 21

EPI, also a role in chronic pancreatitis

Question 22

What is replacing TLI to diagnose pancreatitis in cats?

Answer 22

fPLI

Question 23

What assay is currently used for dogs and cats?

Answer 23

DGGR lipase

Question 24

What is the problem with the pancreatitis snap test?

Answer 24

Not quantitative

Question 25

How can you monitor fibrosis from chronic pancreatitis?

Answer 25

Hyaluronic acid

Question 26

Which conditions can also increase hyaluronic acid?

Answer 26

Liver and kidney fibrosis

Question 27

Which species gets EPI?

Answer 27

GSD

Question 28

What do dogs with EPI look like?

Answer 28

Weak, thin, large appetite, fatty stools

Question 29

What is the test to confirm EPI?

Answer 29

TLI

Question 30

Which species especially gets diabetesfrom chronic pancreatitis?

Answer 30

Cats

Question 31

What can pancreatic neoplasia mimic?

Answer 31

Chronic pancreatitis

Question 32

Where does pancreatic neoplasia metastasize to?

Answer 32

Liver

Question 33

Which signalment gets hepatocutaneous syndrome?

Answer 33

Liver tumours in dogs

Question 34

Which cells are effected in neoplasia of the exocrine pancreas?

Answer 34

Islets

Question 35

What is the usual kind of cancer of the exocrine pancrea?

Answer 35

Carcinoma

Question 36

Symptoms of pancreatic islet carcinoma?

Answer 36

Exercise intolerance with hypoglycaemia